Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kok Siong Chen"'
Autor:
Longsha Liu, Thijs A. van Schaik, Kok-Siong Chen, Filippo Rossignoli, Paulo Borges, Vladimir Vrbanac, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/0147e1c4c66745aca653b8bc05b417bf
Autor:
Longsha Liu, Thijs A. van Schaik, Kok-Siong Chen, Filippo Rossignoli, Paulo Borges, Vladimir Vrbanac, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Glioblastoma (GBM) is the most aggressive and common type of malignant brain tumor diagnosed in adults. Preclinical immunocompetent mouse tumor models generated using mouse tumor cells play a pivotal role in testing the therapeutic efficacy of emergi
Externí odkaz:
https://doaj.org/article/c16ec3ad8efe4e1c9db3f6de3db24ff5
Autor:
Zachary H. Houston, Jens Bunt, Kok-Siong Chen, Simon Puttick, Christopher B. Howard, Nicholas L. Fletcher, Adrian V. Fuchs, Jiwei Cui, Yi Ju, Gary Cowin, Xin Song, Andrew W. Boyd, Stephen M. Mahler, Linda J. Richards, Frank Caruso, Kristofer J. Thurecht
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 727-738 (2020)
Externí odkaz:
https://doaj.org/article/3fb1a902064e45d0828820d915363b4e
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Combinatory treatments using surgery, radiotherapy and/or chemotherapy together with immunotherapy have shown encouraging results for specific subsets of tumors, but a significant proportion of tumors remains unsusceptible. Some of these inconsistenc
Externí odkaz:
https://doaj.org/article/2afd9c649b214a8c9f384dc7ef75cfdd
Autor:
Laura Morcom, Timothy J Edwards, Eric Rider, Dorothy Jones-Davis, Jonathan WC Lim, Kok-Siong Chen, Ryan J Dean, Jens Bunt, Yunan Ye, Ilan Gobius, Rodrigo Suárez, Simone Mandelstam, Elliott H Sherr, Linda J Richards
Publikováno v:
eLife, Vol 10 (2021)
Corpus callosum dysgenesis (CCD) is a congenital disorder that incorporates either partial or complete absence of the largest cerebral commissure. Remodelling of the interhemispheric fissure (IHF) provides a substrate for callosal axons to cross betw
Externí odkaz:
https://doaj.org/article/a0f288c043a6456c9f5d9a9386ffe164
Autor:
Nobuhiko Kanaya, Yohei Kitamura, Maria Lopez Vazquez, Arnaldo Franco, Kok-Siong Chen, Thijs A. van Schaik, Touraj Aligholipour Farzani, Paulo Borges, Toru Ichinose, Waleed Seddiq, Shinji Kuroda, Genevieve Boland, Nusrat Jahan, David Fisher, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Science Translational Medicine. 15
Oncolytic virus therapy has shown activity against primary melanomas; however, its efficacy in brain metastases remains challenging, mainly because of the delivery and immunosuppressive nature of tumors in the brain. To address this challenge, we fir
Autor:
Kok-Siong Chen, Clemens Reinshagen, Thijs A. Van Schaik, Filippo Rossignoli, Paulo Borges, Natalia Claire Mendonca, Reza Abdi, Brennan Simon, David A. Reardon, Hiroaki Wakimoto, Khalid Shah
Publikováno v:
Sci Transl Med
The administration of inactivated tumor cells is known to induce a potent antitumor immune response; however, the efficacy of such an approach is limited by its inability to kill tumor cells before inducing the immune responses. Unlike inactivated tu
Autor:
Nada M. Zaidan, Norah A Aldrak, Haya A. Alfassam, Samar M Alkoblan, Essam A. Tawfik, Rana Abou-Khalil, Kok-Siong Chen, Dunia A. Alzahrani, Abdulaziz Almalik, Shahad H Albrahim, Khalid Shah
Publikováno v:
Immunotherapy. 13:1215-1229
Over recent years, tremendous advances in immunotherapy approaches have been observed, generating significant clinical progress. Cancer immunotherapy has been shown, in different types of blood cancers, to improve the overall survival of patients. Im
Autor:
Thijs A. van Schaik, Lucia Moreno-Lama, Touraj Aligholipour Farzani, Mian Wang, Kok-Siong Chen, Wanlu Li, Ling Cai, Yu Shrike Zhang, Khalid Shah
Publikováno v:
Biomedicine & Pharmacotherapy. 162:114665
Autor:
Hiroaki Wakimoto, Massimo Dominici, Deepak Bhere, Filippo Rossignoli, Anna Valeria Samarelli, Kok-Siong Chen, Na Song, Jasneet Kaur Khalsa, Rachele Ciccocioppo, Ilenia Mastrolia, Khalid Shah
Publikováno v:
Stem Cells (Dayton, Ohio)
The Coronavirus disease 2019 (COVID‐19) pandemic has grown to be a global public health crisis with no safe and effective treatments available yet. Recent findings suggest that severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the c