Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Kok P. M. van Kessel"'
Autor:
Elena Boero, Ronald D. Gorham, Emmet A. Francis, Jonathan Brand, Lay Heng Teng, Dennis J. Doorduijn, Maartje Ruyken, Remy M. Muts, Christian Lehmann, Admar Verschoor, Kok P. M. van Kessel, Volkmar Heinrich, Suzan H. M. Rooijakkers
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract The complement system provides vital immune protection against infectious agents by labeling them with complement fragments that enhance phagocytosis by immune cells. Many details of complement-mediated phagocytosis remain elusive, partly be
Externí odkaz:
https://doaj.org/article/f3257d792e8348a29273436ad98c183c
Autor:
Leonardo Cecotto, Daphne A. C. Stapels, Kok P. M. van Kessel, Michiel Croes, Zeldali Lourens, H. Charles Vogely, Bart C. H. van der Wal, Jos A. G. van Strijp, Harrie Weinans, Saber Amin Yavari
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundDespite the extensive use of silver ions or nanoparticles in research related to preventing implant-associated infections (IAI), their use in clinical practice has been debated. This is because the strong antibacterial properties of silver
Externí odkaz:
https://doaj.org/article/f7e8031665bb4d918c2fa8e3bcb00e72
Autor:
Lisanne de Vor, Coco R. Beudeker, Anne Flier, Lisette M. Scheepmaker, Piet C. Aerts, Daniel C. Vijlbrief, Mireille N. Bekker, Frank J. Beurskens, Kok P. M. van Kessel, Carla J. C. de Haas, Suzan H. M. Rooijakkers, Michiel van der Flier
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Central line associated bloodstream infections (CLABSI) with Staphylococcus epidermidis are a major cause of morbidity in neonates, who have an increased risk of infection because of their immature immune system. As especially preterm neonates suffer
Externí odkaz:
https://doaj.org/article/c668e35acaa743bdbfdce9f1042fa215
Autor:
Elena Boero, Ana Rita Cruz, Werner Pansegrau, Cinzia Giovani, Suzan H. M. Rooijakkers, Kok P. M. van Kessel, Jos A. G. van Strijp, Fabio Bagnoli, Andrea G. O. Manetti
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Staphylococcal protein A (SpA) is a multifunctional, highly conserved virulence factor of Staphylococcus aureus. By binding the Fc portion of all human IgG subclasses apart from IgG3, SpA interferes with antibody and complement deposition on the bact
Externí odkaz:
https://doaj.org/article/00b0ba48b38a4c0e85a24c32fe1d2ac2
Autor:
Hedzer Hoekstra, Francisco Romero Pastrana, Hendrik P. J. Bonarius, Kok P. M. van Kessel, Goffe S. Elsinga, Neeltje Kooi, Herman Groen, Jan Maarten van Dijl, Girbe Buist
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 70-82 (2018)
Staphylococcus aureus is a serious public health burden causing a wide variety of infections. Earlier detection of such infections could result in faster and more directed therapies that also prevent resistance development. Human monoclonal antibodie
Externí odkaz:
https://doaj.org/article/445f80b8ec294e29b7d8c7978fdb3084
Autor:
Elena Boero, Iris Brinkman, Thessely Juliet, Eline van Yperen, Jos A. G. van Strijp, Suzan H. M. Rooijakkers, Kok P. M. van Kessel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils play a key role in the human immune response to Staphylococcus aureus infections. These professional phagocytes rapidly migrate to the site of infection to engulf bacteria and destroy them via specialized intracellular killing mechanisms.
Externí odkaz:
https://doaj.org/article/f274e502173e44db8a8c1dffdb99fe4b
Autor:
Angelino T. Tromp, Yuxi Zhao, Ilse Jongerius, Erik C. J. M. Heezius, Pauline Abrial, Maartje Ruyken, Jos A. G. van Strijp, Carla J. C. de Haas, András N. Spaan, Kok P. M. van Kessel, Thomas Henry, Pieter-Jan A. Haas
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 9 (2020)
Bacterial pathogens have evolved to secrete strong anti-inflammatory proteins that target the immune system. It was long speculated whether these virulence factors could serve as therapeutics in diseases in which abnormal immune activation plays a ro
Externí odkaz:
https://doaj.org/article/884250d0a4b64443b263765e26fc16a7
Autor:
Eija Nissilä, Pipsa Hakala, Katarzyna Leskinen, Angela Roig, Shahan Syed, Kok P. M. Van Kessel, Jari Metso, Carla J. C. De Haas, Päivi Saavalainen, Seppo Meri, Angeliki Chroni, Jos A. G. Van Strijp, Katariina Öörni, Matti Jauhiainen, T. Sakari Jokiranta, Karita Haapasalo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The alternative pathway (AP) of complement is constantly active in plasma and can easily be activated on self surfaces and trigger local inflammation. Host cells are protected from AP attack by Factor H (FH), the main AP regulator in plasma. Although
Externí odkaz:
https://doaj.org/article/50fa5f1b73774b2ebc5f09103838760f
Autor:
Ana Rita Cruz, Arthur E. H. Bentlage, Robin Blonk, Carla J. C. de Haas, Piet C. Aerts, Lisette M. Scheepmaker, Inge G. Bouwmeester, Anja Lux, Jos A. G. van Strijp, Falk Nimmerjahn, Kok P. M. van Kessel, Gestur Vidarsson, Suzan H. M. Rooijakkers
Immunoglobulin G molecules are crucial for the human immune response against bacterial infections. IgGs can trigger phagocytosis by innate immune cells, like neutrophils. To do so, IgGs should bind to the bacterial surface via their variable Fab regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b688e563ab2407fb2c4920b13fefc220
https://doi.org/10.1101/2022.01.21.477287
https://doi.org/10.1101/2022.01.21.477287
Autor:
Seline A, Zwarthoff, Simone, Magnoni, Piet C, Aerts, Kok P M, van Kessel, Suzan H M, Rooijakkers
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2227
Understanding how human complement proteins interact with human antibodies is important for the development of antibody therapies and understanding autoimmune diseases. At present, many groups use baby rabbit serum as a source of complement because,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ecea8642dfdd87c2ce710f886edd7694
https://pubmed.ncbi.nlm.nih.gov/33847927
https://pubmed.ncbi.nlm.nih.gov/33847927