Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kok Long Ang"'
Autor:
Kok Long Ang, Ferenc A. Antoni
Publikováno v:
Cellular Signalling. 14:445-452
Characterisation of cyclic nucleotide-hydrolysing phosphodiesterases (PDEs) in recombinant systems has highlighted regulatory properties indicative of distinct physiological roles for these enzymes. The present study investigated the role of PDEs in
Autor:
Maria M. Magiera, Alison J. McLean, George S. Baillie, Trudy A. Kohout, Robert J. Lefkowitz, Ian McPhee, Marco Conti, Kok Long Ang, Miles D. Houslay, Stephen J. Perry, William E. Miller
Publikováno v:
Science. 298:834-836
Catecholamines signal through the β 2 -adrenergic receptor by promoting production of the second messenger adenosine 3′,5′-monophosphate (cAMP). The magnitude of this signal is restricted by desensitization of the receptors through their binding
Publikováno v:
Cancer letters. 225(1)
Most gastric adenocarcinomas arise as a longterm complication of Helicobacter pylori infection of the stomach, but the high prevalence of this infection limits the cost-effectiveness of antibiotic eradication as a cancer prevention strategy. Here we
Autor:
Deborah L. Segaloff, Ya-Xiong Tao, Hiromitsu Shinozaki, Kok Long Ang, Viktor Butnev, Marco Conti
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(3)
Activating mutations of the human lutropin/choriogonadotropin receptor (hLHR), a Gs-coupled receptor, have been identified in young boys with gonadotropin-independent precocious puberty (testotoxicosis). The properties of these mutants have typically
Autor:
Kok-Long, Ang, Ferenc A, Antoni
Publikováno v:
Journal of neurochemistry. 81(3)
The hydrolysis of cyclic nucleotide second messengers takes place through multiple cyclic nucleotide phosphodiesterases (PDEs). The significance of this diversification is not fully understood. Here we report the differential regulation of low K(m) C