Inhibition of hemopoiesis in vitro by neuroblastoma-derived gangliosides

Autor: Sietsma, H, Nijhof, W, Dontje, B, Vellenga, E, Kamps, WA, Kok, JW

Publikováno v: Cancer Research, 58(21), 4840-4844. AMER ASSOC CANCER RESEARCH

Hemopoiesis is disturbed in bone marrow-involving cancers like leukemia and neuroblastoma. Shedding of gangliosides by tumor cells may contribute to this tumor-induced bone marrow suppression, We studied in vitro the inhibitory effects of murine neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::49f25ec119531046b544e863eb05a8ac
https://research.rug.nl/en/publications/53998cfa-37ae-4fdf-a999-4d840d2f73a0

Dynamical properties of membranes: Application of fluorescent lipid analogs

Autor: HOEKSTRA, D, BABIA, T, ZEGERS, M, ZAAL, K, ARTS, EGJM, KOK, JW, PedrosodeLima, MC, Duzgunes, N, Hoekstra, D

Publikováno v: TRAFFICKING OF INTRACELLULAR MEMBRANES: FROM MOLECULAR SORTING TO MEMBRANE FUSION, 11-33
STARTPAGE=11;ENDPAGE=33;TITLE=TRAFFICKING OF INTRACELLULAR MEMBRANES: FROM MOLECULAR SORTING TO MEMBRANE FUSION
Trafficking of Intracellular Membranes: ISBN: 9783642795497

Recent advances in studies involving the structure and dynamics of membranes have shown that fluorescently-tagged lipid probes have become versatile and, occasionally, indispensable tools in this area of research. These probes are applied in investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b2a1765f88b763f6d380845feadcf7
https://research.rug.nl/en/publications/7879302f-cf23-4f2f-8914-ea4cdba4525b

INTRACELLULAR SITES INVOLVED IN THE BIOGENESIS OF BILE CANALICULI IN HEPATIC CELLS

Autor: ZAAL, KJM, KOK, JW, SORMUNEN, R, ESKELINEN, S, HOEKSTRA, D

Publikováno v: European Journal of Cell Biology, 63(1), 10-19. ELSEVIER GMBH, URBAN & FISCHER VERLAG

Studies in hepatoma cells and hepatocytes have revealed that the biogenesis of bile canalicular membrane involves microvilli-lined vesicles (MLV), which are formed in well diferentiated cells. The vesicles grow as a function of time and are presumabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::c6aa555c85f794fb8ddc0200adedc48d
https://research.rug.nl/en/publications/63302c3c-55ae-4e2e-a8d2-fe1455183bca

DIFFERENTIAL METABOLISM AND TRAFFICKING OF SPHINGOLIPIDS IN DIFFERENTIATED VERSUS UNDIFFERENTIATED HT29 CELLS

Autor: BABIA, T, KOK, JW, HULSTAERT, C, DEWEERD, H, HOEKSTRA, D

Publikováno v: International Journal of Cancer, 54(5), 839-845. Wiley

Trafficking and metabolism of sphingolipids were examined in undifferentiated (G+) and differentiated (G+ reversed) HT29 human colon adenocarcinoma cell lines. Metabolic experiments employing a fluorescently labeled sphingolipid precursor, 6-[N-(7-ni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::76e308a330b8cc6b9bf51eb79e969d50
https://research.rug.nl/en/publications/59d176ac-0448-4b4a-bff5-0186095a34bb

COATED ENDOSOMAL VESICLES - SORTING AND RECYCLING COMPARTMENT FOR TRANSFERRIN IN BHK CELLS

Autor: ESKELINEN, S, KOK, JW, SORMUNEN, R, HOEKSTRA, D

Publikováno v: European Journal of Cell Biology, 56(2), 210-222. ELSEVIER GMBH, URBAN & FISCHER VERLAG

We have investigated receptor-mediated endocytosis of transferrin (Tf) in baby hamster kidney (BHK) cells, using fluorescence and electron microscopy, and by carrying out colocalization experiments with clathrin antibodies and a fluorescently tagged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::9cf03b67370706e48875adacd7f347d7
https://research.rug.nl/en/publications/8418b9b5-f422-43f3-9564-3bc6614c9b3c