Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kojiro Ishibashi"'
Autor:
Kazuki Nakai, Hancheng Lin, Shotaro Yamano, Shinya Tanaka, Sho Kitamoto, Hitoshi Saitoh, Kenta Sakuma, Junpei Kurauchi, Eilma Akter, Masamitsu Konno, Kojiro Ishibashi, Ryo Kamata, Akihiro Ohashi, Jun Koseki, Hirotaka Takahashi, Hideshi Yokoyama, Yukihiro Shiraki, Atsushi Enomoto, Sohei Abe, Yoku Hayakawa, Tetsuo Ushiku, Michihiro Mutoh, Yasuyuki Fujita, Shunsuke Kon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Normal epithelial cells exert their competitive advantage over RasV12-transformed cells and eliminate them into the apical lumen via cell competition. However, the internal or external factors that compromise cell competition and provoke car
Externí odkaz:
https://doaj.org/article/6f44e420616648b8bbcf9f4de854cbbb
Autor:
Yui Kato, Yuya Matsuda, Takuya Uto, Daisuke Tanaka, Kojiro Ishibashi, Takeru Ishizaki, Akio Ohta, Akiko Kobayashi, Masaharu Hazawa, Richard W. Wong, Kazuaki Ninomiya, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract During the long-term storage of cells, it is necessary to inhibit ice crystal formation by adding cryoprotectants. Non-cell-permeable cryoprotectants have high osmotic pressure which dehydrates cells, indirectly suppressing intracellular ice
Externí odkaz:
https://doaj.org/article/9449e3f5122546cb88e316f044078289
Autor:
Takeru Ishizaki, Yasuto Takeuchi, Kojiro Ishibashi, Noriko Gotoh, Eishu Hirata, Kosuke Kuroda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Cryopreservation of tissues is a tough challenge. Cryopreservation is categorized into slow-freezing and vitrification, and vitrification has recently been recognized as a suitable method for tissue cryopreservation. On the contrary, some re
Externí odkaz:
https://doaj.org/article/c0d1f32238a242d2b972a88c7f963744
Autor:
Yui Kato, Takuya Uto, Daisuke Tanaka, Kojiro Ishibashi, Akiko Kobayashi, Masaharu Hazawa, Richard W. Wong, Kazuaki Ninomiya, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-10 (2021)
Zwitterionic solutions have potential applications as cryoprotectants, but the relationship between structure and performance is underexplored. Here a family of zwitterions are assessed in terms of cytotoxicity, cryopreservation performance, and effe
Externí odkaz:
https://doaj.org/article/c9d877e392ae4a79addbe5c091681759
Autor:
Riki Kadokawa, Tetsuo Fujie, Gyanendra Sharma, Kojiro Ishibashi, Kazuaki Ninomiya, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Trimethylglycine (TMG) is a cheap, natural, and highly biocompatible compound. Therefore, it has been used in the fields of food and life sciences, but the application of solid TMG is limited to utilisation as an “additive”. In the prese
Externí odkaz:
https://doaj.org/article/8250c6de5dab40d5b67f7e837fecc7fa
Autor:
Tetsuo Komori, Yui Kato, Kojiro Ishibashi, Kazuaki Ninomiya, Naoki Wada, Daisuke Hirose, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda
Publikováno v:
Journal of Ionic Liquids, Vol 2, Iss 1, Pp 100027- (2022)
Zwitterions have been attracting great attention and the synthesis of carboxylate-type zwitterions is complicated than those of sulfonate-type zwitterions. Therefore, we focused on one-step synthesis of carboxylate-type zwitterions with a lactone, re
Externí odkaz:
https://doaj.org/article/fea1534569d7432eaff1b38b44591d24
Autor:
Eishu Hirata, Kojiro Ishibashi, Shinji Kohsaka, Keiko Shinjo, Shinya Kojima, Yutaka Kondo, Hiroyuki Mano, Seiji Yano, Etsuko Kiyokawa, Erik Sahai
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101480- (2020)
Summary: Brain metastasis is an ineffective process, and many cancer cells enter into an indolent state following extravasation in the brain. Single cell RNA sequencing of melanoma brain metastases reveals that non-proliferating brain metastatic mela
Externí odkaz:
https://doaj.org/article/075886fa79f04fe4ac3e688ca6e5417d
Autor:
Hirotaka Watanabe, Kojiro Ishibashi, Hiroki Mano, Sho Kitamoto, Nanami Sato, Kazuya Hoshiba, Mugihiko Kato, Fumihiko Matsuzawa, Yasuto Takeuchi, Takanobu Shirai, Susumu Ishikawa, Yuka Morioka, Toshiaki Imagawa, Kazuyasu Sakaguchi, Suguru Yonezawa, Shunsuke Kon, Yasuyuki Fujita
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3721-3729 (2018)
Summary: p53 is a tumor suppressor protein, and its missense mutations are frequently found in human cancers. During the multi-step progression of cancer, p53 mutations generally accumulate at the mid or late stage, but not in the early stage, and th
Externí odkaz:
https://doaj.org/article/7b3d5f86dea4489d8d609ac4b73d0b9d
Autor:
Eishu Hirata, Kojiro Ishibashi, Toshiya Ichinose, Riki Kadokawa, Ryo Mizutani, Sadahiro Iwabuchi, Sumihito Togi, Hiroki Ura, Keiko Shinjo, Jun Nakayama, Shigeki Nanjo, Yo Niida, Yutaka Kondo, Shinichi Hashimoto, Erik Sahai, Seiji Yano, Mitsutoshi Nakada
Interactions between cancer cells and glial cells play a crucial role in the formation of brain metastases; however, there are few methods to stably analyse these events in vitro over a long period of time. Here, we develop a simple and stable cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b6e4f75d5a5dc97b3295422489df37
https://doi.org/10.21203/rs.3.rs-2853151/v1
https://doi.org/10.21203/rs.3.rs-2853151/v1
Autor:
Kazuaki Ninomiya, Daisuke Tanaka, Takuya Uto, Eishu Hirata, Richard W. Wong, Yui Kato, Akiko Kobayashi, Kenji Takahashi, Kosuke Kuroda, Masaharu Hazawa, Kojiro Ishibashi
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-10 (2021)
Cryopreservation of cells is necessary for long periods of storage. However, some cell lines cannot be efficiently cryopreserved, even when optimized commercial cryoprotectants are employed. Previously, we found that a low-toxic synthetic zwitterion