Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Koji Tomobe"'
Autor:
Maruf Mohammad Akbor, Nobuyuki Kurosawa, Hiroki Nakayama, Ayumi Nakatani, Koji Tomobe, Yoichi Chiba, Masaki Ueno, Masashi Tanaka, Yasuyuki Nomura, Masaharu Isobe
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248027 (2021)
Molecular chaperon SERPINA3 colocalizes with accumulated amyloid peptide in Alzheimer's disease (AD) patient's brain. From the QTL analysis, we narrowed down Serpina3 with two SNPs in senescence-accelerated mouse prone (SAMP) 8 strain. Our study show
Externí odkaz:
https://doaj.org/article/6527a5179d894cf3a5838e412749b795
Autor:
Miki Fujii, Chieri Hata, Munetada Ukita, Chie Fukushima, Chihiro Matsuura, Yoshie Kawashima-Ohya, Koji Tomobe, Tsuyoshi Kawashima
Publikováno v:
Archaea, Vol 2016 (2016)
The oxidation of guanine (G) to 7,8-dihydro-8-oxoguanine (GO) forms one of the major DNA lesions generated by reactive oxygen species (ROS). The GO can be corrected by GO DNA glycosylases (Ogg), enzymes involved in base excision repair (BER). Unrepai
Externí odkaz:
https://doaj.org/article/7b59ddf071884b0dbb8dafacdc8fad03
Autor:
Katsuaki Dan, Koji Tomobe, Tatsuo Shinozuka, Keita Takanashi, Takaaki Matsuoka, Kenichi Yamamoto
Background: The mechanism by which reactive oxygen species (ROS) produced by oxidative stress promote cellular senescence has been studied in detail. This study aimed to verify the preventive or therapeutic effects of mesenchymal stem cell-derived ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce7441536562f42d8f5eed00413db6d
https://doi.org/10.21203/rs.3.rs-268923/v1
https://doi.org/10.21203/rs.3.rs-268923/v1
Autor:
Masaharu Isobe, Masashi Tanaka, Koji Tomobe, Hiroki Nakayama, Ayumi Nakatani, Yoichi Chiba, Yasuyuki Nomura, Masaki Ueno, Nobuyuki Kurosawa, Maruf Mohammad Akbor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248027 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248027 (2021)
Molecular chaperon SERPINA3 colocalizes with accumulated amyloid peptide in Alzheimer’s disease (AD) patient’s brain. From the QTL analysis, we narrowed down Serpina3 with two SNPs in senescence-accelerated mouse prone (SAMP) 8 strain. Our study
Publikováno v:
American Journal of Analytical Chemistry. :88-97
The sensitive method for the simultaneous determination of eight atypical antipsychotic drugs (risperidone, olanzapine, quetiapine, clozapine, ziprasidone, perospirone, aripiprazole and blonanserin) in human serum has been developed based on a high-p
Autor:
Kou Honma, Tetsuji Hosono, Tatsuo Shinozuka, Mayumi Okutsu, Yoko Kunisue, Nobuhiko Naruki, Masaru Terada, Koji Tomobe, Kohei Agei, Keiko Tonooka
Publikováno v:
Forensic Science International. 265:182-185
A high-performance liquid chromatography-tandem mass spectrometry (LC/MS/MS) with electrospray ionization (ESI) procedure for the simultaneous determination of nine local anesthetic drugs (procaine, mepivacaine, lidocaine, ropivacaine, oxybuprocaine,
Autor:
Yu Ikeda, Hikari Minoshima, Youichi Itoh, Yoshiaki Omata, Tomoaki Ishikawa, Tsuyoshi Kawashima, Yoshie Kawashima-Ohya, Mai Satoh, Miki Fujii, Koji Tomobe
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:481-485
The genome of the facultative anaerobic thermoacidophilic archaeon Thermoplasma volcanium contains the open-reading frames (ORFs) tvsod and tvogg, which are predicted to encode a putative superoxide dismutase and an 8-oxoguanine DNA glycosylase, resp
Autor:
Yoshie Kawashima-Ohya, Hiroka Suzuki, Kota Makino, Toshiharu Nakajima, Runa Omachi, Tsuyoshi Kawashima, Koji Tomobe
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:1982-1985
The bursa of Fabricius (BF) is a unique primary lymphoid organ, and among vertebrates is unique to birds. Despite its importance to the immune systems of various avian species, little is known of the molecular mechanisms underlying early BF developme
Publikováno v:
Archives of Gerontology and Geriatrics. 57:417-422
SAMP8 exhibits accelerated aging and a short lifespan. Insulin-like growth factor-1 receptor (IGF-1R)/FOXO pathway is associated with aging. Phosphorylation of IGF-1R, Akt, and FOXO1 was found to be increased during aging in the liver of SAMR1 normal
Autor:
Koji Tomobe, Munetada Ukita, Chie Fukushima, Miki Fujii, Chieri Hata, Tsuyoshi Kawashima, Chihiro Matsuura, Yoshie Kawashima-Ohya
Publikováno v:
Archaea, Vol 2016 (2016)
The oxidation of guanine (G) to 7,8-dihydro-8-oxoguanine (GO) forms one of the major DNA lesions generated by reactive oxygen species (ROS). The GO can be corrected by GO DNA glycosylases (Ogg), enzymes involved in base excision repair (BER). Unrepai