Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Koji Shibasaki"'
Autor:
Mitsutaka Yakabe, Koji Shibasaki, Tatsuya Hosoi, Shoya Matsumoto, Kazuhiro Hoshi, Masahiro Akishita, Sumito Ogawa
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Frailty is a state of increased vulnerability to poor resolution of homeostasis following a stress. Early diagnosis and intervention of frailty are essential to prevent its adverse outcomes. However, simple diagnostic criteria hav
Externí odkaz:
https://doaj.org/article/b87f577ea19c473984203118a20ca723
Autor:
Yu Hirata, Kazuhiro Nomura, Daisuke Kato, Yoshihisa Tachibana, Takahiro Niikura, Kana Uchiyama, Tetsuya Hosooka, Tomoaki Fukui, Keisuke Oe, Ryosuke Kuroda, Yuji Hara, Takahiro Adachi, Koji Shibasaki, Hiroaki Wake, Wataru Ogawa
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Although immobility is a common cause of muscle atrophy, the mechanism underlying this causality is unclear. We here show that Krüppel-like factor 15 (KLF15) and IL-6 are upregulated in skeletal muscle of limb-immobilized mice and that mice with KLF
Externí odkaz:
https://doaj.org/article/bb1cf92118f84aac8bc9507c468e1c5e
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101173- (2021)
The transient receptor potential vanilloid 2 (TRPV2) ion channel is activated by a chemical ligand (2-aminoethoxydiphenyl borate; 2-APB), noxious heat and mechanical stimulation. In a heterologous mammalian cell expression system, the oxidant chloram
Externí odkaz:
https://doaj.org/article/1648b014572d4b7991b1212b02522703
Publikováno v:
BMC Geriatrics, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Female sex is an important factor predisposing individuals to frailty. Appropriate nutrition is one of the most effective ways to prevent older adults from developing frailty; Sex-related differences have also been detected in the
Externí odkaz:
https://doaj.org/article/a2a40e2c3046471b838a2e2c02d84625
Autor:
Hidetaka Matsumoto, Ryo Mukai, Junki Hoshino, Mai Oda, Toshiyuki Matsuzaki, Yasuki Ishizaki, Koji Shibasaki, Hideo Akiyama
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0246115 (2021)
Pachychoroid spectrum diseases have been described as a new clinical entity within the spectrum of macular disorders. "Pachychoroid" is defined as choroidal thickening associated with dilated outer choroidal vessels often showing retinal pigment epit
Externí odkaz:
https://doaj.org/article/75c6f491424143778a9f9b0fe420fa99
TRPV4-dependent induction of a novel mammalian cold-inducible protein SRSF5 as well as CIRP and RBM3
Autor:
Takanori Fujita, Hiroaki Higashitsuji, Hisako Higashitsuji, Yu Liu, Katsuhiko Itoh, Toshiharu Sakurai, Takahiro Kojima, Shuya Kandori, Hiroyuki Nishiyama, Motoi Fukumoto, Manabu Fukumoto, Koji Shibasaki, Jun Fujita
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Cold-inducible RNA-binding protein (CIRP) and RNA-binding motif protein 3 (RBM3) are two evolutionarily conserved RNA-binding proteins that are structurally related to hnRNPs and upregulated in response to moderately low temperatures in mamm
Externí odkaz:
https://doaj.org/article/12d3b3e3e6ed4b84adc0a680091d2cde
Autor:
Miho Sato-Hashimoto, Tomomi Nozu, Riho Toriba, Ayano Horikoshi, Miho Akaike, Kyoko Kawamoto, Ayaka Hirose, Yuriko Hayashi, Hiromi Nagai, Wakana Shimizu, Ayaka Saiki, Tatsuya Ishikawa, Ruwaida Elhanbly, Takenori Kotani, Yoji Murata, Yasuyuki Saito, Masae Naruse, Koji Shibasaki, Per-Arne Oldenborg, Steffen Jung, Takashi Matozaki, Yugo Fukazawa, Hiroshi Ohnishi
Publikováno v:
eLife, Vol 8 (2019)
A characteristic subset of microglia expressing CD11c appears in response to brain damage. However, the functional role of CD11c+ microglia, as well as the mechanism of its induction, are poorly understood. Here we report that the genetic ablation of
Externí odkaz:
https://doaj.org/article/8bca47c9b3664098b6aa35fd634ec088
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200143 (2018)
The aim is to investigate the relationship between a positive outcome on rehabilitation after hip fracture and behavioral psychological symptoms of dementia (BPSD) transition during rehabilitation. This study is a retrospective cohort study based on
Externí odkaz:
https://doaj.org/article/bb2dbcdb13bb4e54b7489ce82534dea2
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53109 (2013)
We previously reported that CD44-positive cells were candidates for astrocyte precursor cells in the developing cerebellum, because cells expressing high levels of CD44 selected by fluorescence-activated cell sorting (FACS) gave rise only to astrocyt
Externí odkaz:
https://doaj.org/article/7cdaa59f257140169950cc2001c82d58
Autor:
Hidetaka Matsumoto, Koji Shibasaki, Motokazu Uchigashima, Amane Koizumi, Masashi Kurachi, Yasuhiro Moriwaki, Hidemi Misawa, Koichiro Kawashima, Masahiko Watanabe, Shoji Kishi, Yasuki Ishizaki
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42841 (2012)
It has been long speculated that specific signals are transmitted from photoreceptors to the retinal pigment epithelium (RPE). However, such signals have not been identified. In this study, we examined the retinal expression and localization of acety
Externí odkaz:
https://doaj.org/article/fa15583199c946ff802dfbde369e1725