Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Koji Ozasa"'
Autor:
Shingo Kobari, Takato Kusakabe, Masatoshi Momota, Takayuki Shibahara, Tomoya Hayashi, Koji Ozasa, Hideaki Morita, Kenji Matsumoto, Hirohisa Saito, Shuichi Ito, Etsushi Kuroda, Ken J. Ishii
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Vaccine adjuvants are traditionally used to augment and modulate the immunogenicity of vaccines, although in many cases it is unclear which specific molecules contribute to their stimulatory activity. We previously reported that both subcutaneous and
Externí odkaz:
https://doaj.org/article/e46abc3c4835404a8f47a34fabbb8a4c
Autor:
Koji Ozasa, Burcu Temizoz, Takato Kusakabe, Shingo Kobari, Masatoshi Momota, Cevayir Coban, Shuichi Ito, Kouji Kobiyama, Etsushi Kuroda, Ken J. Ishii
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Extracellular host-derived DNA, as one of damage associated molecular patterns (DAMPs), is associated with allergic type 2 immune responses. Immune recognition of such DNA generates the second messenger cyclic GMP-AMP (cGAMP) and induces type-2 immun
Externí odkaz:
https://doaj.org/article/ebe222340df34f2792d91e9bff5cd672
Publikováno v:
Pediatrics international : official journal of the Japan Pediatric SocietyREFERENCES. 64(1)
Autor:
Hiroyuki Mochizuki, Satoshi Kusuda, Kenji Okada, Shigemi Yoshihara, Hiroyuki Furuya, Eric A. F. Simões, Hideomi Asanuma, Hiroshi Yoshida, Masahiko Katayose, Takashi Imamura, Hiroshi Suzumura, Youko Honma, Jichi Medical, Kenichi Maruyama, Yasushi Ohki, Koji Ozasa, Akiyoshi Nariai, Atsushi Uchiyama, Hideko Uryu, Shigeharu Hosono, Masatoshi Kondo, Yasuharu Kawase, Kazunari Ikeda, Atsushi Naito, Yuki Minami, Tomohiko Nakamura, Atsushi Baba, Yoshihisa Nagayama, Hisashi Kaneda, Shigeru Ohki, Masami Shiraii, Yuto Henmi, Chizuko Suzuki, Kuniko Ieda, Taihei Tanaka, Yoshinori Kono, Kashiro Nisizawa, Fusako Niwa, Hisato Ito, Yasuyuki Tokunaga, Yoshinobu Takada, Yoshihide Nishikawa, Ikuo Nagata, Yasuhisa Kajino, Shinichi Watabe, Hiroyuki Yoshio, Nobumasa Takahashi, Nobutaka Sasaki, Michiko Hayashidani, Hiroshi Tateishi, Kenji Matsushita, Masatoshi Nakamura, Hideki Nakayama, Go Yamamoto, Noriaki Kanemitsu, Toshimitsu Takayanagi, Ayumi Sato, Satoshi Ibara
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 196:29-38
Respiratory syncytial virus (RSV) induces not only infantile recurrent wheezing but also potentially atopic asthma.To test the effect of RSV infection on development of subsequent atopic asthma, we evaluated whether palivizumab, an anti-RSV monoclona
Autor:
Tomohiro Kanuma, Takato Kusakabe, Kouji Kobiyama, Taiki Aoshi, Kenji Kabashima, Takahiro Nagatake, Burcu Temizoz, Christine Xing’Er Koo, Shingo Kobari, Etsushi Kuroda, Masayuki Hayashi, Koji Ozasa, Steven F. Ziegler, Ken Ishii, Tomohiro Kurosaki, Wataru Ise, Naoki Takemura, Satoshi Uematsu, Keiichi Ohata, Cevayir Coban, Yasuo Morimoto, Yoichiro Iwakura, Saeko Nakajima, Jun Kunisawa, Masanori Horie
Publikováno v:
Immunity. 45:1299-1310
Particulate pollution is thought to function as an adjuvant that can induce allergic responses. However, the exact cell types and immunological factors that initiate the lung-specific immune responses are unclear. We found that upon intratracheal ins
Autor:
Burcu Temizoz, Kouji Kobiyama, Etsushi Kuroda, Taiki Aoshi, Takuya Yamamoto, Koji Ozasa, Tomohiro Kanuma, Ken Ishii, Masatoshi Momota
Publikováno v:
European Journal of Immunology. 46:1142-1151
CpG oligodeoxynucleotide (ODN) is one of promising nucleic acid-based adjuvants. We recently improved its ability to enhance CD8(+) T-cell responses to coadministered protein antigen without conjugation or emulsion, by forming a nanoparticulate compl
Autor:
Burcu Temizoz, Ken Ishii, Kouji Kobiyama, Taiki Aoshi, Etsushi Kuroda, Koji Ozasa, Nao Jounai, Keiichi Ohata
Publikováno v:
European Journal of Immunology
Agonists for TLR9 and Stimulator of IFN Gene (STING) act as vaccine adjuvants that induce type-1 immune responses. However, currently available CpG oligodeoxynucleotide (ODN) (K-type) induces IFNs only weakly and STING ligands rather induce type-2 im
Autor:
Shohei, Kubota, Asako, Nozawa, Takanori, Yanai, Koji, Ozasa, Satomi, Mori, Kazuyuki, Kurihara
Publikováno v:
Arerugi = [Allergy]. 66(6)
We report a case of jellyfish allergy diagnosed via an oral food challenge. A 14-year-old boy had no history of jellyfish stings and had been eating commercially available jellyfish products twice yearly for the past 5-6 years. Five minutes after eat
Publikováno v:
Current Topics in Environmental Health and Preventive Medicine ISBN: 9789811003493
It is thought that particle pollutants exacerbate allergic responses that are defined as highly increased airway cellular responses and IgE production. These particulates are nanometer- to micrometer-sized particles such as particulate matter 2.5 (PM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494bbf087a2b401e549a1eaa2a622810
https://doi.org/10.1007/978-981-10-0351-6_5
https://doi.org/10.1007/978-981-10-0351-6_5
Autor:
Taiki Aoshi, Masayuki Hayashi, Etsushi Kuroda, Koji Ozasa, Kouji Kobiyama, Cevayir Coban, Takato Kusakabe, Masatoshi Momota, Ken Ishii, Shingo Kobari, Yasunari Haseda
Publikováno v:
Scientific Reports
Nasal vaccination has the potential to elicit systemic and mucosal immunity against pathogens. However, split and subunit vaccines lack potency at stimulating mucosal immunity, and an adjuvant is indispensable for eliciting potent mucosal immune resp