Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Koji Ogata"'
Autor:
Yuta Kanazawa, Shunsuke Saito, Ikuko Shibasaki, Taiki Matsuoka, Shotaro Hirota, Shouhei Yokoyama, Yasuyuki Kanno, Masahiro Tezuka, Go Tsuchiya, Taisuke Konishi, Koji Ogata, Hirotsugu Fukuda
Publikováno v:
Surgical Case Reports, Vol 9, Iss 1, Pp 1-4 (2023)
Abstract Background Left ventricle aneurysm (LVA) as a sequela to myocardial infarction or iatrogenic injury is required surgical treatment with full median sternotomy. Herein, we report a case of successful surgical treatment of left ventricle aneur
Externí odkaz:
https://doaj.org/article/3aba918d54e7459d97ad06809bd8b82e
Autor:
Shunsuke Saito, Toshimi Sairenchi, Shotaro Hirota, Ken Niitsuma, Shohei Yokoyama, Yasuyuki Kanno, Yuta Kanazawa, Masahiro Tezuka, Yusuke Takei, Go Tsuchiya, Taisuke Konishi, Ikuko Shibasaki, Koji Ogata, Osamu Monta, Yasushi Tsutsumi, Hirotsugu Fukuda
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 10, p 355 (2022)
Background This study compared the clinical outcomes of transcatheter (TAVR) and surgical (SAVR) aortic valve replacements, focusing on postoperative valvular performance assessed by echocardiography. Method and Results A total of 425 patients who un
Externí odkaz:
https://doaj.org/article/6921426ee00d42639503c28493d8ee17
Autor:
Koji Ogata, Tetsu Isomura, Shinji Kawata, Hiroshi Yamashita, Hideo Kubodera, Shoshana J. Wodak
Publikováno v:
Molecules, Vol 15, Iss 6, Pp 4382-4400 (2010)
This work proposes a computational procedure for structure-based lead generation and optimization, which relies on the complementarity of the protein-ligand interactions. This procedure takes as input the known structure of a protein-ligand complex.
Externí odkaz:
https://doaj.org/article/c19c53be679045bd837cb83f8bb62abb
Publikováno v:
Molecules, Vol 23, Iss 2, p 425 (2018)
The octanol–water partition coefficient (logPow) is an important index for measuring solubility, membrane permeability, and bioavailability in the drug discovery field. In this paper, the logPow values of 58 compounds were predicted by alchemical f
Externí odkaz:
https://doaj.org/article/32e268717d1743d09cc66df514124a9b
Autor:
Tatsuki Matsumoto, Madoka Urushido, Haruna Ide, Masayuki Ishihara, Kazu Hamada-Ode, Yoshiko Shimamura, Koji Ogata, Kosuke Inoue, Yoshinori Taniguchi, Takafumi Taguchi, Taro Horino, Shimpei Fujimoto, Yoshio Terada
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126229 (2015)
BackgroundHeat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. Autophagy protects cells from many types of stress and is thoug
Externí odkaz:
https://doaj.org/article/8dfe963c09c74c95a1f1f63133dca410
Autor:
Yoshio Terada, Keiji Inoue, Tatsuki Matsumoto, Masayuki Ishihara, Kazu Hamada, Yoshiko Shimamura, Koji Ogata, Kosuke Inoue, Yoshinori Taniguchi, Taro Horino, Takashi Karashima, Kenji Tamura, Hideo Fukuhara, Shimpei Fujimoto, Masayuki Tsuda, Taro Shuin
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80850 (2013)
Nephrotoxicity is a frequent and major limitation in cisplatin (CDDP)-based chemotherapy. 5-Aminolevulinic acid (ALA) is widely distributed in animal cells, and it is a precursor of tetrapyrole compounds such as heme that is fundamentally important i
Externí odkaz:
https://doaj.org/article/1c2ee7b3f6524845918e446566a44571
Autor:
Hiromasa Sakaguchi, Koji Ogata, Tetsu Isomura, Shoko Utsunomiya, Yoshihisa Yamamoto, Kazuyuki Aihara
Publikováno v:
Entropy, Vol 18, Iss 10, p 365 (2016)
A structure-based lead optimization procedure is an essential step to finding appropriate ligand molecules binding to a target protein structure in order to identify drug candidates. This procedure takes a known structure of a protein-ligand complex
Externí odkaz:
https://doaj.org/article/e94aec0d86de4aa6a94515936143d56e
Autor:
Koji Ogata
Publikováno v:
The Journal of Physical Chemistry B. 125:1072-1084
A grid-based principal component analysis method (GBPCA) has been developed and implemented to investigate the modes of collective molecules present in the cube in the grid system from their trajectories using molecular dynamics (MD) simulation. This
Autor:
Shunsuke Saito, Ikuko Shibasaki, Taiki Matsuoka, Ken Niitsuma, Shotaro Hirota, Yasuyuki Kanno, Yuta Kanazawa, Masahiro Tezuka, Yusuke Takei, Go Tsuchiya, Taisuke Konishi, Koji Ogata, Hirotsugu Fukuda
Publikováno v:
Interactive CardioVascular and Thoracic Surgery. 35
OBJECTIVES In patients with cardiogenic shock, delayed surgery after stabilization of haemodynamics and improvement in end-organ function by mechanical circulatory support is known to yield better outcomes than emergency surgery. We aimed to investig
Autor:
Muhammad Imran, Koji Ogata, Saba Waqar, Nazia Bibi, Sundus Javed, Habib Bokhari, Zobia Noreen, Mahmood Ahmed, Muhammad Muddassar, Asma Amjad
Publikováno v:
RSC Advances. 10:16061-16070
The enzyme urease is an essential colonizing factor of the notorious carcinogenic pathogen Helicobacter pylori (H. pylori), conferring acid resistance to the bacterium. Recently, antibiotic resistant strains have emerged globally with little to no al