Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Koji Nagaoka"'
Autor:
Yoshihiro Kushihara, Shota Tanaka, Yukari Kobayashi, Koji Nagaoka, Miyu Kikuchi, Takahide Nejo, Erika Yamazawa, Shohei Nambu, Kazuha Kugasawa, Hirokazu Takami, Shunsaku Takayanagi, Nobuhito Saito, Kazuhiro Kakimi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundGlioblastoma (GBM) is a highly lethal brain tumor. The effectiveness of temozolomide (TMZ) treatment in GBM is linked to the methylation status of O6-methyl-guanine DNA methyltransferase (MGMT) promoter. Patients with unmethylated MGMT prom
Externí odkaz:
https://doaj.org/article/ca6009eeb817459d85daa3d3d501a4ee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/3b55e8f5868f4467b800b2230990a450
Autor:
Yukari Kobayashi, Kazuhiro Kakimi, Koji Nagaoka, Shumpei Ishikawa, Tomoko Saito, Kazuyoshi Takeda, Hiroto Katoh, Yoshikazu Totsuka
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/827b400f43c14afdacfd161f01db6f23
Autor:
Taisuke Ishii, Imari Mimura, Koji Nagaoka, Akihiro Naito, Takehito Sugasawa, Ryohei Kuroda, Daisuke Yamada, Yasuharu Kanki, Haruki Kume, Tetsuo Ushiku, Kazuhiro Kakimi, Tetsuhiro Tanaka, Masaomi Nangaku
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-18 (2022)
Abstract Chronic kidney disease (CKD) affects kidney cancer patients’ mortality. However, the underlying mechanism remains unknown. M2-like macrophages have pro-tumor functions, also exist in injured kidney, and promote kidney fibrosis. Thus, it is
Externí odkaz:
https://doaj.org/article/fea4fd389da749cf83f77efa217dce65
Autor:
Pengwen Chen, Wenqian Yang, Koji Nagaoka, George Lo Huang, Takuya Miyazaki, Taehun Hong, Shangwei Li, Kazunori Igarashi, Kazuyoshi Takeda, Kazuhiro Kakimi, Kazunori Kataoka, Horacio Cabral
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract Treatment of immunologically cold tumors is a major challenge for immune checkpoint inhibitors (ICIs). Interleukin 12 (IL‐12) can invigorate ICIs against cold tumors by establishing a robust antitumor immunity. However, its toxicity and sy
Externí odkaz:
https://doaj.org/article/1923dbcd7fa84cce9709053810b8c054
Autor:
Noriyuki Saito, Yasuyoshi Sato, Hiroyuki Abe, Ikuo Wada, Yukari Kobayashi, Koji Nagaoka, Yoshihiro Kushihara, Tetsuo Ushiku, Yasuyuki Seto, Kazuhiro Kakimi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Understanding the tumor microenvironment (TME) and anti-tumor immune responses in gastric cancer are required for precision immune-oncology. Taking advantage of next-generation sequencing technology, the feasibility and reliability of transc
Externí odkaz:
https://doaj.org/article/f8cbbf03b9be468da664682c89d6beea
Autor:
Akihiro Hosoi, Kazuyoshi Takeda, Koji Nagaoka, Tamaki Iino, Hirokazu Matsushita, Satoshi Ueha, Shin Aoki, Kouji Matsushima, Masato Kubo, Teppei Morikawa, Kazutaka Kitaura, Ryuji Suzuki, Kazuhiro Kakimi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a76c14697c4c468abac1a2cb93525325
Autor:
Noriyuki Saito, Yukari Kobayashi, Koji Nagaoka, Yoshihiro Kushihara, Yasuyoshi Sato, Ikuo Wada, Kazuhiro Kakimi, Yasuyuki Seto
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101167- (2021)
An in-depth understanding of the tumor microenvironment (TME) is required for the development of improved combination immunotherapies for gastric cancer. Recently, we classified these cancers into four main types defined by their immunological attrib
Externí odkaz:
https://doaj.org/article/5083fbf3126d4e1a8af51c48ba6dc19f
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/6bd2534a2a99417c8a53fa5dcbfe9593
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/97f9ac77ae964815911cf5b58be6b8f4