Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Koji Nagahama"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Cells are often passively encapsulated in hydrogels for a wide range of applications. Here, the authors report on a method of incorporating the cells into the hydrogel using bioorthogonal click reactions to link azide-modified cells with biocompatibl
Externí odkaz:
https://doaj.org/article/2cfd3d3c2b024e1ca5b20f643a7bddd4
Publikováno v:
ACS Applied Materials & Interfaces. 14:34443-34454
Metal-organic frameworks (MOFs) are porous materials with adsorption, storage, and separation capabilities due to their high specific surface areas and large pore volumes. MOFs are thus used in biomedical applications, and MOF nanoparticles have been
Autor:
Kimika Ono, Manami Sumiya, Naohiro Yoshinobu, Tatsuya Dode, Tokitaka Katayama, Natsumi Ueda, Koji Nagahama
Publikováno v:
ACS Applied Bio Materials. 5:471-482
Desferrioxamine (DFO) upregulates HIF-1α and stimulates expression of vascular endothelial growth factor (VEGF), thereby accelerating neovascularization. As DFO acts primarily upon surrounding vein endothelial cells to stimulate angiogenesis, the an
Publikováno v:
ACS applied materialsinterfaces. 14(47)
Biohybrid materials, which are defined as engineered functional materials combining living components with nonliving synthetic materials, are considered promising bioactive materials for applications in in vivo tissue engineering. However, the ration
Publikováno v:
ACS Macro Letters. 10:1073-1079
Regarding synthetic self-healing materials, as healing reactions occur at the molecular level, bond formation occurs when healing chemicals are nanometer distances apart. However, motility of healing chemicals in materials is quite limited, permittin
Autor:
Mitsuo Inui, Yuta Hamada, Nana Sejima, Natsumi Ueda, Tokitaka Katayama, Kimika Ono, Koji Nagahama
Publikováno v:
Nanoscale advances. 4(12)
Inspired by the structural and chemical features of naturally occurring importin/exportin that allows them to pass through the nuclear pore complexes, we successfully developed an artificial nuclear-exporting nanosystem capable of eliminating compoun
Publikováno v:
Biomacromolecules. 22(10)
Systemic enzyme-prodrug therapy (EPT) using nanofactories, nanoparticles encapsulating prodrug-activating enzymes, is a promising concept for anticancer therapy. However, systemic delivery systems can be problematic. As nanofactories are typically ca
Autor:
Yuka Sanada, Koji Nagahama, Yuka Kimura, Kimika Ono, Seika Aoyama, Tokitaka Katayama, Natsumi Ueda
Publikováno v:
Biomaterials science. 8(2)
Hypersialylation is the aberrant expression of sialic acid in cell surface glycans and is pervasive in cancer cells. Recent studies have shown that hypersialylation provides a microenvironment conducive to cancer progression, mediated by the interact
Autor:
Tomoki Maeda, Koji Nagahama, Makoto Miyazaki, Atsushi Hotta, Kenji Hirashima, Naruki Kurokawa
Publikováno v:
Polymer. 115:246-254
A PEG-based copolymer with a high PEG ratio was synthesized and the sol-gel transition temperature (Tgel) around the physiological temperature (25 °C–37 °C) was achieved. Specifically, we synthesized a triblock PEG copolymer of poly ( d , l -lact
Publikováno v:
Advanced Biology. 5:2000106