Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Koji Matsukawa"'
Autor:
Yuya Kishino, Koji Matsukawa, Taisei Matsumoto, Ryota Miyazaki, Tomoko Wakabayashi, Takashi Nonaka, Fuyuki Kametani, Masato Hasegawa, Tadafumi Hashimoto, Takeshi Iwatsubo
Publikováno v:
The Journal of biological chemistry. 298(8)
Aberrant cytoplasmic accumulation of an RNA-binding protein, fused in sarcoma (FUS), characterizes the neuropathology of subtypes of ALS and frontotemporal lobar degeneration, although the effects of post-translational modifications of FUS, especiall
Autor:
Koji Matsukawa, Michail S. Kukharsky, Tadafumi Hashimoto, Sei-Kyoung Park, Naruaki Watanabe, Sangeun Park, Susan W. Liebman, Takeshi Iwatsubo, Tatyana A. Shelkovnikova
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Pathological changes involving TDP-43 protein (‘TDP-43 proteinopathy’) are typical for several neurodegenerative diseases, including frontotemporal lobar degeneration (FTLD). FTLD-TDP cases are characterized by increased binding of TDP-43 to an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb05de62e4815040894e418d403252a
Autor:
Ryoko Ihara, Yuya Kishino, Koji Matsukawa, Tomoko Wakabayashi, Taisei Matsumoto, Tadafumi Hashimoto, Naruaki Watanabe, Takeshi Iwatsubo, Hayato Kunugi
Publikováno v:
Human Molecular Genetics. 27:1353-1365
Aggregation of fused in sarcoma (FUS) protein, and mutations in FUS gene, are causative to a range of neurodegenerative disorders including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. To gain insights into the molecular mechanism
Publikováno v:
Japanese Journal of Farm Work Research. 50:115-126
Autor:
Koji Matsukawa, Masayuki Miura, Ryoko Ihara, Tomoko Wakabayashi, Taisei Matsumoto, Tadafumi Hashimoto, Takeshi Iwatsubo, Takahiro Chihara
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive and selective loss of motor neurons. Causative genes for familial ALS (fALS), e.g., TARDBP or FUS/TLS, have been found, among which mutations within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65574253b46d6d375119e2e7a0d11bf0
https://europepmc.org/articles/PMC5095402/
https://europepmc.org/articles/PMC5095402/
Autor:
Tatyana A. Shelkovnikova, Haiyan An, Takeshi Iwatsubo, Annamaria Quintiero, Koji Matsukawa, Michail S. Kukharsky, Tadafumi Hashimoto, Vladimir L. Buchman, Taisei Matsumoto
Publikováno v:
Molecular Neurodegeneration
Background Mutations in calcium-responsive transactivator (CREST) encoding gene have been recently linked to ALS. Similar to several proteins implicated in ALS, CREST contains a prion-like domain and was reported to be a component of paraspeckles. Re
Autor:
Tadafumi Hashimoto, Takeshi Iwatsubo, Masayuki Miura, Tomoko Wakabayashi, Koji Matsukawa, Hayato Kunugi, Takahiro Chihara, Ryoko Ihara, Hirokazu Uchigami
Publikováno v:
Alzheimer's & Dementia. 9
tau phosphorylation.Results: Six months high fat diet increased Abeta40 in the brains ofB6C wild type mice. On the other hand, high fat diet increased plasma Abeta levels in APP/PS1 mice, but not in wild type mice. Moreover, tau phosphorylation was h
Autor:
Koji Matsukawa, Takahiro Chihara, Shoji Tsuji, Masayuki Miura, Tadafumi Hashimoto, Tomoko Wakabayashi, Hayato Kunugi, Yusei Nagata, Takeshi Iwatsubo, Ryoko Ihara, Erina Kuranaga
Publikováno v:
Human molecular genetics. 22(22)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive and selective loss of motor neurons. The discovery of mutations in the gene encoding an RNA-binding protein, TAR DNA-binding protein of 43 kD (TDP-43), i
Autor:
Taisei Matsumoto, Koji Matsukawa, Naruaki Watanabe, Yuya Kishino, Hayato Kunugi, Ryoko Ihara, Tomoko Wakabayashi, Tadafumi Hashimoto, Takeshi Iwatsubo
Publikováno v:
Human Molecular Genetics; 4/15/2018, Vol. 27 Issue 8, p1353-1365, 13p
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