Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Koji L. Ode"'
Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation
Autor:
Kazuhiro Kon, Koji L. Ode, Tomoyuki Mano, Hiroshi Fujishima, Riina R. Takahashi, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Kyoko Matsuzawa, Shota Y. Yoshida, Junko Yoshida Garçon, Mari Kaneko, Yuta Shinohara, Rikuhiro G. Yamada, Shoi Shi, Kazunari Miyamichi, Kenta Sumiyama, Hiroshi Kiyonari, Etsuo A. Susaki, Hiroki R. Ueda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The homeostatic regulation of sleep is characterized by rebound sleep after prolonged wakefulness, but the molecular and cellular mechanisms underlying this regulation are still unknown. In this study, we show that Ca2+/calmodulin-dependent
Externí odkaz:
https://doaj.org/article/1820ed7e972241e4b90b7d9e83e720d1
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Sleep is an evolutionarily conserved phenotype shared by most of the animals on the planet. Prolonged wakefulness will result in increased sleep need or sleep pressure. However, its mechanisms remain elusive. Recent findings indicate that Ca2+ signal
Externí odkaz:
https://doaj.org/article/5c555befd9ab49c9ae4af4765b178cf7
Autor:
Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, Yuki Arisato, Rei-ichiro Ohno, Maki Ukai-Tadenuma, Junko Yoshida Garçon, Mari Kaneko, Shoi Shi, Hideki Ukai, Kazunari Miyamichi, Takashi Okada, Kenta Sumiyama, Hiroshi Kiyonari, Hiroki R. Ueda
Publikováno v:
PLoS Biology, Vol 20, Iss 10 (2022)
The reduced sleep duration previously observed in Camk2b knockout mice revealed a role for Ca2+/calmodulin-dependent protein kinase II (CaMKII)β as a sleep-promoting kinase. However, the underlying mechanism by which CaMKIIβ supports sleep regulati
Externí odkaz:
https://doaj.org/article/c422f3677b6849ceb5f7d2c1b49d07ab
Autor:
Yasuhiro Yamamoto, Haruka Chino, Satoshi Tsukamoto, Koji L. Ode, Hiroki R. Ueda, Noboru Mizushima
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Ciliogenesis is a tightly regulated process, although the role of selective autophagy is unclear. Here, the authors show NIMA-related kinase 9 controls actin network stabilization and subsequently ciliogenesis by targeting myosin MYH9 for autophagic
Externí odkaz:
https://doaj.org/article/75e721e981164b0eac18bb692e449bb8
Autor:
Etsuo A. Susaki, Chika Shimizu, Akihiro Kuno, Kazuki Tainaka, Xiang Li, Kengo Nishi, Ken Morishima, Hiroaki Ono, Koji L. Ode, Yuki Saeki, Kazunari Miyamichi, Kaoru Isa, Chihiro Yokoyama, Hiroki Kitaura, Masako Ikemura, Tetsuo Ushiku, Yoshihiro Shimizu, Takashi Saito, Takaomi C. Saido, Masashi Fukayama, Hirotaka Onoe, Kazushige Touhara, Tadashi Isa, Akiyoshi Kakita, Mitsuhiro Shibayama, Hiroki R. Ueda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-22 (2020)
Tissue clearing has revolutionised histology, but limited penetration of antibodies and stains into thick tissue segments is still a bottleneck. Here, the authors characterise optically cleared tissue as an electrolyte gel and apply this knowledge to
Externí odkaz:
https://doaj.org/article/fef62ea755aa42a98c3b75bb70274b5d
Autor:
Koji L. Ode, Shoi Shi, Machiko Katori, Kentaro Mitsui, Shin Takanashi, Ryo Oguchi, Daisuke Aoki, Hiroki R. Ueda
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103727- (2022)
Summary: Arm acceleration data have been used to measure sleep–wake rhythmicity. Although several methods have been developed for the accurate classification of sleep–wake episodes, a method with both high sensitivity and specificity has not been
Externí odkaz:
https://doaj.org/article/0a49665828af49c9b21608ccdaa7a4e5
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101946- (2021)
Summary: Chaos behavior has been observed in various cellular and molecular processes. Here, we modeled reversible phosphorylation dynamics to elucidate a design principle for autonomous chaos generation that may arise from generic enzymatic reaction
Externí odkaz:
https://doaj.org/article/4a8eac025e6e4524a79396b49b890a95
Autor:
Koji L. Ode, Hiroki R. Ueda
Publikováno v:
Frontiers in Psychology, Vol 11 (2020)
Sleep is a fundamental property conserved across species. The homeostatic induction of sleep indicates the presence of a mechanism that is progressively activated by the awake state and that induces sleep. Several lines of evidence support that such
Externí odkaz:
https://doaj.org/article/c6e6d202a6d44036b4d890828fb7b15d
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 863-874 (2017)
Previous autonomous pattern-formation models often assumed complex molecular and cellular networks. This theoretical study, however, shows that a system composed of one substrate with multisite phosphorylation and a pair of kinase and phosphatase can
Externí odkaz:
https://doaj.org/article/fb81700d43d04c7e82e78857c07b63f2
Publikováno v:
F1000Research, Vol 8 (2019)
Since Ronald Konopka and Seymour Benzer’s discovery of the gene Period in the 1970s, the circadian rhythm field has diligently investigated regulatory mechanisms and intracellular transcriptional and translation feedback loops involving Period, and
Externí odkaz:
https://doaj.org/article/5bb88c4128a84b93a8ef3b6b4c6a0a87