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pro vyhledávání: '"Koji Itazaki"'
Publikováno v:
European Journal of Pharmacology. 215:259-264
A single class of [ 125 I]angiotensin II ([ 125 I]AII) binding sites was found in porcine aortic smooth muscle membranes. Des-Asp 1 -AII (AIII) and des-Asp 1 -[Ile 8 ]AII were 20 times less potent than AII or [Sar 1 ,Ile 8 ]AII to displace [ 125 I]AI
Autor:
Shigeyuki Nakajima, Masaru Kawakami, Masafumi Fujimoto, Tomoji Kawabata, Toshio Fujishita, Koichi Ohtani, Mariko Hara, Ryuichi Kiyama, Koji Itazaki
Publikováno v:
European journal of pharmacology. 289(2)
Angiotensin AT1 receptor antagonists are divided into two types, surmountable, based on the way they inhibit angiotensin II-induced vasoconstriction. To elucidate what causes the difference, we studied how antagonists associate with and dissociate fr
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