Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Koji Fuji"'
Autor:
Masaru Yanagihashi, Takehisa Hirayama, Mari Shibukawa, Junpei Nagasawa, Koji Fujita, Yuishin Izumi, Mitsuya Morita, Kota Bokuda, Kazushi Takahashi, Kazuaki Kanai, Naoki Atsuta, Yohei Iguchi, Masahisa Katsuno, Yoshitaka Murakami, Hiroshi Mitsumoto, Osamu Kano
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-4 (2024)
Abstract Background Primary lateral sclerosis (PLS) is an extremely rare condition; therefore, to date no clinical studies have been conducted. The Primary Lateral Sclerosis Functional Rating Scale (PLSFRS) was developed in the United States of Ameri
Externí odkaz:
https://doaj.org/article/ae86317d1da7451ebdde2298aecee970
Autor:
Kimie Nakamura, Koji Fujita, Motohisa Suzuki, Akiyoshi Kunugi, Yoshihiko Hirozane, Tomonori Kunikata, Bitoku Takahashi, Genta Narazaki, Hirofumi Kondo, Shotaro Haji, Keisuke Hirai, Yuishin Izumi
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundThe rate of disease progression varies widely among patients with amyotrophic lateral sclerosis (ALS). Prognostic assessment using biomarkers is highly anticipated to improve clinical trial design. We aimed to explore the cerebrospinal flui
Externí odkaz:
https://doaj.org/article/2ccff21420db4dd187c0d37609956739
Autor:
Gen Sobue, Hirofumi Maruyama, Keiko Imamura, Yuishin Izumi, Satoshi Morita, Naohiro Egawa, Takashi Ayaki, Makiko Nagai, Kazutoshi Nishiyama, Yasuhiro Watanabe, Ritsuko Hanajima, Koji Fujita, Naoto Takahashi, Akiko Morinaga, Ryosuke Takahashi, Haruhisa Inoue, Naoki Atsuta, Osamu Kano, Takehisa Hirayama, Takao Kiriyama, Hiroshi Kataoka, Takahiko Tokuda, Kazuma Sugie, Takenobu Murakami, Hitoki Nanaura, Masahiro Nakamori, Shotaro Haji, Harutsugu Tatebe, Riko Tabuchi, Motoki Oe, Mihoko Kobayashi, Kasia Lobello
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Introduction Amyotrophic lateral sclerosis (ALS) is a progressive, severe neurodegenerative disease caused by motor neuron death. Development of a medicine for ALS is urgently needed, and induced pluripotent cell-based drug repurposing identified a S
Externí odkaz:
https://doaj.org/article/63d3495d00e24d60a205cd5377da8720
Autor:
Tomoko Tadokoro, Joji Tani, Takushi Manabe, Kei Takuma, Mai Nakahara, Kyoko Oura, Shima Mimura, Koji Fujita, Takako Nomura, Asahiro Morishita, Hideki Kobara, Takashi Himoto, Masafumi Ono, Tsutomu Masaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Portal vein thrombosis (PVT) worsens the long-term prognosis of patients with cirrhosis; however, the optimal treatment remains to be determined. Reports on the efficacy of direct oral anticoagulants are increasing, and further evidence is n
Externí odkaz:
https://doaj.org/article/edf0293d1b7b41aca4d8da2b8ed176f0
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract While the short-term relationship between clouds and aerosols is well known, no adequate data is available to verify the longer-term, annual to decadal, relationship. It is important to quantify the aerosol–cloud interaction (ACI) for miti
Externí odkaz:
https://doaj.org/article/e4715f835d444ee5a0cb29b8477ed59b
Autor:
Tomoko Tadokoro, Takako Nomura, Koji Fujita, Takushi Manabe, Kei Takuma, Mai Nakahara, Kyoko Oura, Shima Mimura, Joji Tani, Asahiro Morishita, Hideki Kobara, Masafumi Ono, Tsutomu Masaki
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Hepatocellular carcinoma (HCC) in autoimmune hepatitis (AIH) was considered rare but is increasing with prolonged prognosis. Its impact on the overall prognosis of AIH is unknown, and treatment has not been established. Aim To inv
Externí odkaz:
https://doaj.org/article/b1e1db6200a24ae49e2fc299f5bec07e
Autor:
Mayu Yoshida, Juntaro Matsuzaki, Koji Fujita, Masamichi Kimura, Tomohiro Umezu, Noi Tokuda, Tomoko Yamaguchi, Masahiko Kuroda, Takahiro Ochiya, Yoshimasa Saito, Kiminori Kimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract There is an unmet need for antifibrotic therapies to prevent the progression of liver cirrhosis. Previously, we conducted an exploratory trial to assess the safety and antifibrotic efficacy of PRI-724, a selective CBP/β-catenin inhibitor, i
Externí odkaz:
https://doaj.org/article/e973a4feb8e641d6a1cfb726a0e430a8
Autor:
Shuichi Ito, Sachi Okuchi, Yasutaka Fushimi, Sayo Otani, Krishna Pandu Wicaksono, Akihiko Sakata, Kanae Kawai Miyake, Hitomi Numamoto, Satoshi Nakajima, Hiroshi Tagawa, Masahiro Tanji, Noritaka Sano, Hiroki Kondo, Rimika Imai, Tsuneo Saga, Koji Fujimoto, Yoshiki Arakawa, Yuji Nakamoto
Publikováno v:
European Radiology Experimental, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Background To evaluate the clinical usefulness of thin-slice echo-planar imaging (EPI)-based diffusion-weighted imaging (DWI) with an on-console distortion correction technique, termed reverse encoding distortion correction DWI (RDC-DWI), in
Externí odkaz:
https://doaj.org/article/24af4dff303e4a2ba12b1792757860a8
Autor:
Eriku Yamada, MD, Tomoyuki Umemoto, MD, PhD, Towako Taguchi, MD, PhD, Iichiroh Onishi, MD, PhD, Akiko Yamamoto, MD, Kazuya Tsukamoto, MD, Takuya Ibara, PhD, Toru Sasaki, MD, PhD, Hidetoshi Kaburagi, MD, PhD, Yasuhiro Maejima, MD, PhD, Tetsuo Sasano, MD, PhD, Kenichi Ohashi, MD, PhD, Toshitaka Yoshii, MD, PhD, Akimoto Nimura, MD, PhD, Koji Fujita, MD, PhD
Publikováno v:
JSES International, Vol 8, Iss 2, Pp 349-354 (2024)
Background: Cardiac amyloidosis is a fatal disease of severe heart failure caused by the accumulation of amyloid in the myocardium. This disease is often advanced by the time cardiac symptoms appear; therefore, early detection and treatment are criti
Externí odkaz:
https://doaj.org/article/c5c56a6c79ac4c16b3b9a73fbb38ac47
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Alcohol abuse is associated with several diseases, such as hepatocellular carcinoma, cirrhosis, and extrahepatic malignancies. Recently, we reported albumin platelet product (APP) and modified APP (mAPP) as novel indices of liver fibrosis st
Externí odkaz:
https://doaj.org/article/f8ecefc171f34a13a830096e2ec4758c