Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Koji, Murao"'
Autor:
Jingya Lyu, Hitomi Imachi, Kensaku Fukunaga, Seisuke Sato, Toshihiro Kobayashi, Takanobu Saheki, Salimah Japar, Hisakazu Iwama, Yuta Matsumura, Miyo Ozaki, Takafumi Yoshimura, Koji Murao
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5474-5484 (2022)
Glucagon-like peptide-1 receptor agonist (GLP-1RA) has been clinically proven to protect endothelial function. Previously, we demonstrated that endothelial NO synthase (eNOS) was activated by high-density lipoprotein (HDL) via its scavenger receptor
Externí odkaz:
https://doaj.org/article/a630a56a424b4be4bcbefd0af99c440b
Autor:
Salimah Japar, Kensaku Fukunaga, Toshihiro Kobayashi, Hitomi Imachi, Seisuke Sato, Takanobu Saheki, Tomohiro Ibata, Takafumi Yoshimura, Kim Lam Soh, Swee Leong Ong, Zamri Muhamed, Koji Murao
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 14, Iss 1, Pp 1-8 (2022)
Abstract Background During Ramadan fasting, postprandial hyperglycemia is commonly observed after iftar (break of fast at sunset) meal. d-allulose is a rare sugar and is reported to have several health benefits, including the suppression of increase
Externí odkaz:
https://doaj.org/article/5c2b83a2881a44db841c92e506dfc1a6
Autor:
Di Liu, Wan-Pin Sun, Jing-Wei Chen, Yan Jiang, Rong Xue, Lin-Hui Wang, Koji Murao, Guo-Xing Zhang
Publikováno v:
Clinical and Experimental Hypertension, Vol 43, Iss 5, Pp 462-473 (2021)
Background: Signal transduction of Angiotensin II (Ang II) induced autophagy and its role in Ang II–induced dysfunction of HUVECs are still unclear. Methods: HUVECs are stimulated with different doses of Ang II (10-9-10-5 mol/L) for different time
Externí odkaz:
https://doaj.org/article/012076bd3bb04cc5955e8573746aa13f
Autor:
Fumi Kikuchi, Takanobu Saheki, Hitomi Imachi, Toshihiro Kobayashi, Kensaku Fukunaga, Tomohiro Ibata, Seisuke Sato, Natsuki Ban, Jingya Lyu, Salimah Japar, Koji Murao
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-7 (2021)
Abstract Background Immune checkpoint inhibitors have recently become widely used for the management of advanced cancer patients. During the development of immune checkpoint inhibitors (ICPIs), it was quickly recognized that they are associated with
Externí odkaz:
https://doaj.org/article/ae0d0a3439474766a7f0511a0ef19e71
Autor:
Jingya Lyu, Hitomi Imachi, Kensaku Fukunaga, Seisuke Sato, Toshihiro Kobayashi, Tao Dong, Takanobu Saheki, Mari Matsumoto, Hisakazu Iwama, Huanxiang Zhang, Koji Murao
Publikováno v:
Molecular Metabolism, Vol 34, Iss , Pp 16-26 (2020)
Objective: Adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1) influences hepatic cholesterol transportation. Accumulation of hepatic cholesterol leads to fatty liver disease, which is improved by glucagon-like peptide 1 (GLP-1) in d
Externí odkaz:
https://doaj.org/article/7ae39236ba2242d9a3f7a94bda3c86e8
Autor:
Makoto Arioka, Kosuke Koyano, Yasuhiro Nakao, Miyo Ozaki, Shinji Nakamura, Hiroyuki Kiuchi, Hitoshi Okada, Susumu Itoh, Koji Murao, Takashi Kusaka
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 60:177-183
Background Exposing blood serum samples to ambient white light-emitting diode (WLED) light may accelerate bilirubin photoisomer production. We previously demonstrated the quantitative effect of bilirubin configurational isomers (BCI) on direct biliru
Autor:
Jingya Lyu, Hitomi Imachi, Kensaku Fukunaga, Seisuke Sato, Tomohiro Ibata, Toshihiro Kobayashi, Tao Dong, Takuo Yoshimoto, Kazuko Yonezaki, Hiromi Nagata, Hisakazu Iwama, Koji Murao
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1906-1915 (2018)
In pancreatic β cells, ABCA1, a 254 kDa membrane protein, affects cholesterol homeostasis and insulin secretion. Angiotensin II, as the main effector of the renin–angiotensin system, decreases glucose-stimulated insulin secretion (GSIS). We examin
Externí odkaz:
https://doaj.org/article/67e3f76ce2264de4a596a2c4424d3e6e
Autor:
Kazuko Yonezaki, Toshihiro Kobayashi, Hitomi Imachi, Takuo Yoshimoto, Fumi Kikuchi, Kensaku Fukunaga, Seisuke Sato, Tomohiro Ibata, Nao Yamaji, Jingya Lyu, Tao Dong, Koji Murao
Publikováno v:
Journal of Medical Case Reports, Vol 12, Iss 1, Pp 1-5 (2018)
Abstract Background Recently, immune checkpoint inhibitors have widely been used for the management of advanced melanoma. However, high-grade immune-related adverse events can occur, particularly with combination immunotherapy. We report a case of a
Externí odkaz:
https://doaj.org/article/897fbd26609f471882b4a56659994a01
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 87:163-170
Glucotoxicity, impaired insulin secretion, suppression of insulin gene expression, and apoptosis, in pancreatic β-cells caused by chronic hyperglycemia is a key component of the pathogenesis of type 2 diabetes. Recently, it has been reported that ra
Autor:
Yan-Yan Wang, Yi-Yi Song, Wen-Yi Jiang, Hao-Tian Zhang, Jing-Wei Chen, Koji Murao, Wan-Ping Sun, Guo-Xing Zhang
Objective:Thrombospondin-1 (TSP-1) plays an important role in platelet activation and aggregation and aggravates thrombosis. Chronic stress can cause a variety of diseases, including coagulation disorders, increased thrombosis, atherosclerosis, and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af35cdaf734cdc1b09720d01458842e
https://doi.org/10.1101/2023.04.13.536820
https://doi.org/10.1101/2023.04.13.536820