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pro vyhledávání: '"Koichiro Saruhashi"'
Autor:
Ayako Aihara, Takumi Iwawaki, Natsuki Abe-Fukasawa, Keiichiro Otsuka, Koichiro Saruhashi, Takumi Mikashima, Taito Nishino
Publikováno v:
Journal of Biological Chemistry. 298:101779
Although 3D cell culture models are considered to reflect the physiological microenvironment and exhibit high concordance with in vivo conditions, one disadvantage has been that cell proliferation is slower in 3D culture as compared to 2D culture. Ho
Publikováno v:
Cancer Science
Anticancer drug discovery efforts have used 2-D cell-based assay models, which fail to forecast in vivo efficacy and result in a lower success rate of clinical approval. Recent 3-D cell culture models are expected to bridge the gap between 2-D and in