Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Koichiro Nishino"'
Autor:
Asato Sekiya, Ken Takasawa, Yoshikazu Arai, Shin-ichi Horike, Hidenori Akutsu, Akihiro Umezawa, Koichiro Nishino
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 620-630 (2022)
Introduction: Human induced pluripotent stem cells (hiPSCs) are useful tools for reproducing neural development in vitro. However, each hiPSC line has a different ability to differentiate into specific lineages, known as differentiation propensity, r
Externí odkaz:
https://doaj.org/article/713ff3db5b2d4258af590dc1c99b51be
Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors
Autor:
Koichiro Nishino, Yoshikazu Arai, Ken Takasawa, Masashi Toyoda, Mayu Yamazaki-Inoue, Tohru Sugawara, Hidenori Akutsu, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Akihiro Umezawa
Publikováno v:
Regenerative Therapy, Vol 9, Iss , Pp 71-78 (2018)
Human induced pluripotent stem cells (iPSCs) are established by introducing several reprogramming factors, such as OCT3/4, SOX2, KLF4, c-MYC. Because of their pluripotency and immortality, iPSCs are considered to be a powerful tool for regenerative m
Externí odkaz:
https://doaj.org/article/89e5fef2aed349748299b4161679e9d0
Autor:
Hiroyuki Imai, Kiyoshi Kano, Wataru Fujii, Ken Takasawa, Shoichi Wakitani, Masato Hiyama, Koichiro Nishino, Ken Takeshi Kusakabe, Yasuo Kiso
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130585 (2015)
Polyploid amphibians and fishes occur naturally in nature, while polyploid mammals do not. For example, tetraploid mouse embryos normally develop into blastocysts, but exhibit abnormalities and die soon after implantation. Thus, polyploidization is t
Externí odkaz:
https://doaj.org/article/60cd8c08f91341058cb98998a16cbf12
Autor:
Yoshiaki Yamagata, Koichiro Nishino, Eiichi Takaki, Shun Sato, Ryo Maekawa, Akira Nakai, Norihiro Sugino
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83612 (2014)
The objective of this study was to characterize the genome-wide DNA methylation profiles of isolated endometrial stromal cells obtained from eutopic endometria with (euESCa) and without endometriosis (euESCb) and ovarian endometrial cysts (choESC). T
Externí odkaz:
https://doaj.org/article/06eeb3ab3d1b4713b30cfdc946034701
Autor:
Koichiro Nishino, Masashi Toyoda, Mayu Yamazaki-Inoue, Yoshihiro Fukawatase, Emi Chikazawa, Hironari Sakaguchi, Hidenori Akutsu, Akihiro Umezawa
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002085 (2011)
Epigenetic reprogramming is a critical event in the generation of induced pluripotent stem cells (iPSCs). Here, we determined the DNA methylation profiles of 22 human iPSC lines derived from five different cell types (human endometrium, placental art
Externí odkaz:
https://doaj.org/article/0a482068ad184801baf1e2363f72a32a
Autor:
Koichiro Nishino, Masashi Toyoda, Mayu Yamazaki-Inoue, Hatsune Makino, Yoshihiro Fukawatase, Emi Chikazawa, Yoriko Takahashi, Yoshitaka Miyagawa, Hajime Okita, Nobutaka Kiyokawa, Hidenori Akutsu, Akihiro Umezawa
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e13017 (2010)
BACKGROUND: Human induced pluripotent stem (iPS) cells are currently used as powerful resources in regenerative medicine. During very early developmental stages, DNA methylation decreases to an overall low level at the blastocyst stage, from which em
Externí odkaz:
https://doaj.org/article/c8579aa4ed5147ff8222381a9ba652e2
Autor:
Yoshikazu Arai1 ayarai@cc.miyazaki-u.ac.jp, Koichiro Nishino1
Publikováno v:
Journal of Toxicological Sciences. 2023, Vol. 48 Issue 11, p571-583. 13p.
Autor:
Kento Shionoya, Takehiro Suzuki, Mako Takada, Kazuki Sato, Shoichi Onishi, Naoshi Dohmae, Koichiro Nishino, Takeshi Wada, Robert J. Linhardt, Toshihiko Toida, Kyohei Higashi
Publikováno v:
International Journal of Biological Macromolecules. 208:333-342
Cartilage in the head of sturgeon or salmon has been gaining attention as a rich source of functional chondroitin sulfate (CS) or proteoglycans. Although the cartilage was found in the heads of other bony fishes, the structure of CS and its core prot
Autor:
Akihiro Umezawa, Yoshikazu Arai, Asato Sekiya, Ken Takasawa, Kohji Okamura, Koichiro Nishino, Hidenori Akutsu
Publikováno v:
Human Cell
The use of human induced pluripotent stem cells (iPSCs), used as an alternative to human embryonic stem cells (ESCs), is a potential solution to challenges, such as immune rejection, and does not involve the ethical issues concerning the use of ESCs
Publikováno v:
The Journal of Veterinary Medical Science
Steroidogenic factor 1 (SF-1) is a nuclear receptor that is important in steroid hormone production, and adrenal and gonad development. The SF-1 gene is highly conserved among most vertebrates. However, dog SF-1 registered in public databases, such a