Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Koichiro Kano"'
Autor:
Noriyuki Endo, Taro Matsumoto, Tomohiko Kazama, Koichiro Kano, Manabu Shimizu, Keinosuke Ryu, Yasuaki Tokuhashi, Kazuyoshi Nakanishi
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 50-59 (2024)
Introduction: Mature adipocyte-derived dedifferentiated fat cells (DFATs) represent a subtype of multipotent cells that exhibit comparable phenotypic and functional characteristics to adipose-derived stem cells (ASCs). In this study, we assessed the
Externí odkaz:
https://doaj.org/article/df54457dec2f4bd99e256b9c69aadaad
Autor:
Hirokatsu Sawada, Tomohiko Kazama, Yuki Nagaoka, Yoshinori Arai, Koichiro Kano, Hiroshi Uei, Yasuaki Tokuhashi, Kazuyoshi Nakanishi, Taro Matsumoto
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background Mesenchymal stem cells (MSCs) are known to have different differentiation potential depending on the tissue of origin. Dedifferentiated fat cells (DFATs) are MSC-like multipotent cells that can be prepared from mature adipocytes b
Externí odkaz:
https://doaj.org/article/c058bce53d9a4c52b54d80256334b44d
Autor:
Kei Utsunomiya, Takashi Maruyama, Satoshi Shimizu, Taro Matsumoto, Morito Endo, Hiroki Kobayashi, Koichiro Kano, Masanori Abe, Noboru Fukuda
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Introduction The implantation of dedifferentiated fat (DFAT) cells has been shown to exert immunosuppressive effects. To develop DFAT cell therapy for antineutrophil cytoplasmic antibody (ANCA) glomerulonephritis, the effects of the implanta
Externí odkaz:
https://doaj.org/article/09823ac166d04f19ac790beaa151a518
Autor:
Koji Tanimoto, Taro Matsumoto, Yuki Nagaoka, Tomohiko Kazama, Chii Yamamoto, Koichiro Kano, Masahiro Nagaoka, Shu Saito, Yasuaki Tokuhashi, Kazuyoshi Nakanishi
Publikováno v:
Regenerative Therapy, Vol 19, Iss , Pp 35-46 (2022)
Introduction: Mature adipocyte-derived dedifferentiated fat cells (DFATs) are mesenchymal stem cell (MSC)-like cells with high proliferative ability and multilineage differentiation potential. In this study, we first examined whether DFATs can be pre
Externí odkaz:
https://doaj.org/article/af2775bc9a47454e8052a6ed4eaaf671
Autor:
Rei Nakano, Taku Kitanaka, Shinichi Namba, Nanako Kitanaka, Masaki Sato, Yoshiyuki Shibukawa, Yoshikazu Masuhiro, Koichiro Kano, Taro Matsumoto, Hiroshi Sugiya
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229892 (2020)
The specification of cell identity depends on the exposure of cells to sequences of bioactive ligands. All-trans retinoic acid (ATRA) affects neuronal development in the early stage, and it is involved in neuronal lineage reprogramming. We previously
Externí odkaz:
https://doaj.org/article/31899602ae724d0cb4c1c4dd946b9117
Autor:
Yasutaka Murata, Daisuke Obinata, Taro Matsumoto, Yuichiro Ikado, Koichiro Kano, Noboru Fukuda, Kenya Yamaguchi, Satoru Takahashi
Publikováno v:
International Urology and Nephrology. 54:789-797
Purpose Dedifferentiated fat (DFAT) cells are mature adipocyte-derived multipotent cells that can be applicable to cell-based therapy for stress urinary incontinence (SUI). This study developed a persistence SUI model that allows long-term evaluation
Publikováno v:
Genes to Cells. 27:5-13
Here, we established dedifferentiated fat (DFAT) cells from mature bovine adipocytes and then examined the effects of volatile fatty acids on the differentiation of these DFAT cells into adipocytes in vitro. When mature adipocytes were isolated from
Autor:
Megumi, Uetaki, Nobuyuki, Onishi, Yoshinao, Oki, Takatsune, Shimizu, Eiji, Sugihara, Oltea, Sampetrean, Takashi, Watanabe, Hisano, Yanagi, Kiyoshi, Suda, Hiroya, Fujii, Koichiro, Kano, Hideyuki, Saya, Hiroyuki, Nobusue
Publikováno v:
Molecular Biology of the Cell. 33
Cellular differentiation is characterized by changes in cell morphology that are largely determined by actin dynamics. We previously showed that depolymerization of the actin cytoskeleton triggers the differentiation of preadipocytes into mature adip
Autor:
Hirokatsu Sawada, Tomohiko Kazama, Yuki Nagaoka, Yoshinori Arai, Koichiro Kano, Hiroshi Uei, Yasuaki Tokuhashi, Kazuyoshi Nakanishi, Taro Matsumoto
Background Mesenchymal stem cells (MSCs) are known to have different differentiation potential depending on the tissue of origin. Dedifferentiated fat cells (DFATs) are MSC-like multipotent cells that can be prepared from mature adipocytes by ceiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6830244ed8645c475bbe840ac151c54c
https://doi.org/10.21203/rs.3.rs-1437062/v1
https://doi.org/10.21203/rs.3.rs-1437062/v1
Publikováno v:
Genes to Cells
Mature adipocyte‐derived dedifferentiated fat (DFAT) cells have been identified to possess similar multipotency to mesenchymal stem cells, but a method for converting DFAT cells into hepatocytes was previously unknown. Here, using comprehensive ana