Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Koichiro, Tsugawa"'
Autor:
Seock-Ah Im, Javier Cortes, David W. Cescon, Mastura Md Yusof, Hiroji Iwata, Norikazu Masuda, Toshimi Takano, Chiun-Sheng Huang, Chi-Feng Chung, Koichiro Tsugawa, Yeon Hee Park, Koji Matsumoto, Kenichi Inoue, Ava Kwong, Sherene Loi, Wei Fu, Wilbur Pan, Vassiliki Karantza, Hope S. Rugo, Peter Schmid
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract In the phase 3 KEYNOTE-355 study (NCT02819518), pembrolizumab plus chemotherapy demonstrated statistically significant and clinically meaningful improvements in progression-free survival (PFS) and overall survival (OS) versus placebo plus ch
Externí odkaz:
https://doaj.org/article/779d501670554a368c8218be67b35429
Autor:
Masaya Hattori, Norikazu Masuda, Toshimi Takano, Koichiro Tsugawa, Kenichi Inoue, Koji Matsumoto, Takashi Ishikawa, Mitsuya Itoh, Hiroyuki Yasojima, Yuko Tanabe, Keiko Yamamoto, Masato Suzuki, Wilbur Pan, Javier Cortes, Hiroji Iwata
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10280-10293 (2023)
Abstract Pembrolizumab plus chemotherapy improved progression‐free survival (PFS) and overall survival (OS) compared with placebo plus chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic triple‐negative b
Externí odkaz:
https://doaj.org/article/d6b16a26e787415ab7f68851b17b9f97
Autor:
Tomoharu Mori, Yusuke Okamoto, Anfeng Mu, Yoshimi Ide, Akiyo Yoshimura, Noriko Senda, Yukiko Inagaki‐Kawata, Masahiro Kawashima, Hiroyuki Kitao, Eriko Tokunaga, Yasuo Miyoshi, Shozo Ohsumi, Koichiro Tsugawa, Tomohiko Ohta, Toyomasa Katagiri, Shigeru Ohtsuru, Kaoru Koike, Seishi Ogawa, Masakazu Toi, Hiroji Iwata, Seigo Nakamura, Keitaro Matsuo, Minoru Takata
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 6594-6602 (2023)
Abstract The aldehyde degrading function of the ALDH2 enzyme is impaired by Glu504Lys polymorphisms (rs671, termed A allele), which causes alcohol flushing in east Asians, and elevates the risk of esophageal cancer among habitual drinkers. Recent stu
Externí odkaz:
https://doaj.org/article/48f4ba75ffe041cd97eccb6be34eeb79
Autor:
Masataka Sawaki, Naruto Taira, Yukari Uemura, Tsuyoshi Saito, Shinichi Baba, Kokoro Kobayashi, Hiroaki Kawashima, Michiko Tsuneizumi, Noriko Sagawa, Hiroko Bando, Masato Takahashi, Miki Yamaguchi, Tsutomu Takashima, Takahiro Nakayama, Masahiro Kashiwaba, Toshiro Mizuno, Yutaka Yamamoto, Hiroji Iwata, Tatsuya Toyama, Koichiro Tsugawa, Takuya Kawahara, Hirofumi Mukai
Publikováno v:
Breast, Vol 66, Iss , Pp 245-254 (2022)
Purpose: To gauge the effects of treatment practices on prognosis for older patients with HER2-positive early breast cancer, particularly to determine whether adjuvant trastuzumab alone can offer benefit over no adjuvant therapy. This is a prospectiv
Externí odkaz:
https://doaj.org/article/a945b7265854493eb752770a4643139b
Autor:
Kyoko Muto, Issei Tsuchiya, Soo Hyeon Kim, Satoi Nagasawa, Mariko Takishita, Koichiro Tsugawa, Hiroaki Saito, Yusuke Komazaki, Toru Torii, Teruo Fujii, Yutaka Suzuki, Ayako Suzuki, Masahide Seki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract When biologically interpretation of the data obtained from the single-cell RNA sequencing (scRNA-seq) analysis is attempted, additional information on the location of the single cells, behavior of the surrounding cells, and the microenvironm
Externí odkaz:
https://doaj.org/article/0187e26a2944481799d82f894e86683f
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 4203-4212 (2021)
We aimed to determine the dynamic trends in health state utility values (HSUVs) in patients with end-stage breast cancer. We selected 181 patients comprising 137 with primary breast cancer (PBC) and 44 with metastatic breast cancer (MBC) (28 survivor
Externí odkaz:
https://doaj.org/article/003f3e0ca7684991b6dcd4206a732124
Autor:
Takashi Ishikawa, Kentaro Sakamaki, Kazutaka Narui, Hideki Nishimura, Takafumi Sangai, Kentaro Tamaki, Yoshie Hasegawa, Ken-ichi Watanabe, Nobuyasu Suganuma, Shintaro Michishita, Sadatoshi Sugae, Tomohiko Aihara, Koichiro Tsugawa, Hirose Kaise, Naruto Taira, Hirofumi Mukai
Publikováno v:
Breast, Vol 56, Iss , Pp 70-77 (2021)
Background: As Asians are more vulnerable to febrile neutropenia (FN) than Caucasians, evaluations of FN incidence and risk factors in Asians are important for the appropriate use of primary pegfilgrastim (PEG-G). Patients and methods: Japanese breas
Externí odkaz:
https://doaj.org/article/792254e6511546ea843cf2105c7a6567
Autor:
Satoi Nagasawa, Yuta Kuze, Ichiro Maeda, Yasuyuki Kojima, Ai Motoyoshi, Tatsuya Onishi, Tsuguo Iwatani, Takamichi Yokoe, Junki Koike, Motohiro Chosokabe, Manabu Kubota, Hibiki Seino, Ayako Suzuki, Masahide Seki, Katsuya Tsuchihara, Eisuke Inoue, Koichiro Tsugawa, Tomohiko Ohta, Yutaka Suzuki
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Satoi Nagasawa and Yuta Kuze et al. report a multi-omic analysis of ductal carcinoma in situ (DCIS) of the breast, including whole-exome, single-cell, and spatial transcriptome sequencing. They find that for patients under 45 years of age, HER2 ampli
Externí odkaz:
https://doaj.org/article/e426aed0800f44f79e31480b616c2d54
Autor:
Chisato Kunitomi, Miyuki Harada, Yuko Sanada, Akari Kusamoto, Yasushi Takai, Tatsuro Furui, Yuko Kitagawa, Mitsutoshi Yamada, Chie Watanabe, Koichiro Tsugawa, Hiroyuki Nishiyama, Hajime Hosoi, Mitsuru Miyachi, Kazuhiko Sugiyama, Yoshinobu Maeda, Akira Kawai, Toshio Hamatani, Keishi Fujio, Nao Suzuki, Yutaka Osuga
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose In 2017, the first guidelines for fertility preservation in cancer patients were published in Japan. However, the impact of the guidelines remains unknown. Therefore, the authors conducted a nationwide survey on cryopreservation proc
Externí odkaz:
https://doaj.org/article/30e1ddd92d2345a594902258c6f28f4b
Publikováno v:
BMJ Open, Vol 11, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/e7fd9f8b50d74d67ab0d4ad9dcba5c96