Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Koichi Shinhama"'
Publikováno v:
Tetrahedron. 56:7427-7431
An efficient synthetic route to OPC-15161 ( 1 ) was developed via novel pyrazine ring closure promoted by a lithium thiolate anion. The key intermediate ( 4 ) was prepared in a one-pot procedure by treating the methyl ester ( 2 ) with a lithium arylt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65e9ec8ef5950ab858ea2db5c55ac99c
https://doi.org/10.1016/s0040-4020(00)00670-0
https://doi.org/10.1016/s0040-4020(00)00670-0
Autor:
Koichi Shinhama, Jun-ichi Minamikawa, Hitoshi Tone, Katsuhide Matoba, Masayuki Saka, Fumitaka Goto
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 57:407-414
An efficient and practical synthetic route to OPC-15161 (1), a novel inhibitor of superoxide anion generation, is described. Intensive survey on pyrazine ring manipulation has led to the development of multi-kilo synthetic pathway, in which beneficia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82ba9290a455dbc2ceda2026ec1339b
https://doi.org/10.5059/yukigoseikyokaishi.57.407
https://doi.org/10.5059/yukigoseikyokaishi.57.407
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61858de419b4104d8a2ec798baed30eb
https://doi.org/10.1002/chin.199403122
https://doi.org/10.1002/chin.199403122
Autor:
Hitoshi Tone, Koichi Shinhama, Fumitaka Goro, Jun-ichi Minamikawa, Masayuki Saka, Katsuhide Matoba
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c82a10b2fb733dbc971acee8740eb5a
https://doi.org/10.1002/chin.199947288
https://doi.org/10.1002/chin.199947288
Publikováno v:
ChemInform. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7f24380b0baf688553d258516907ca
https://doi.org/10.1002/chin.200323145
https://doi.org/10.1002/chin.200323145
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(1)
The dimeric derivative of aripiprazole was synthesized via the two notable synthetic technologies as a key step: (1) efficient aldehyde bis-arylation by Bi(OTf)(3) and (2) facile Wynberg amination at room temperature. The synthesis has established th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0324cf031c5824c013522dc277ee69ec
https://pubmed.ncbi.nlm.nih.gov/12467618
https://pubmed.ncbi.nlm.nih.gov/12467618
Publikováno v:
ChemInform. 32
An efficient synthetic route to OPC-15161 ( 1 ) was developed via novel pyrazine ring closure promoted by a lithium thiolate anion. The key intermediate ( 4 ) was prepared in a one-pot procedure by treating the methyl ester ( 2 ) with a lithium arylt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b77b942d97f9b2dae08b3b6afdb34e
https://doi.org/10.1002/chin.200101228
https://doi.org/10.1002/chin.200101228
Publikováno v:
The Journal of Organic Chemistry. 45:3125-3128
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88cc3646df2cae76cc462c34913c1a6a
https://doi.org/10.1021/jo01303a041
https://doi.org/10.1021/jo01303a041
Publikováno v:
Bulletin of the Chemical Society of Japan. 53:775-784
Several new sulfonyl or sulfonyl derivativives, thionitrates (RSNO2), sulfonyl nitrites (RSO2NO), were successfully isolated by treating corresponding thiols and sulfinic acids with dinitrogen tetraoxide (N2O4). Spectroscopic data of both stable and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c05be50b029feba3467a43e886e8b5
https://doi.org/10.1246/bcsj.53.775
https://doi.org/10.1246/bcsj.53.775
Publikováno v:
Bulletin of the Chemical Society of Japan. 53:1065-1069
Reactions of various arylamines with either t-butyl thionitrite, t-butyl thionitrate, or p-toluenesulfonyl nitrite in the presence of anhydrous copper(II) halides under mild conditions gave corresponding aryl halides in good yields. This reaction in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb84f5eae296c180b891aacc87270989
https://doi.org/10.1246/bcsj.53.1065
https://doi.org/10.1246/bcsj.53.1065