Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Koichi S Kobayashi"'
Autor:
Morris Nechama, Jeahoo Kwon, Shuo Wei, Adrian Tun-Kyi, Robert S. Welner, Iddo Z. Ben-Dov, Mohamed S. Arredouani, John M. Asara, Chun-Hau Chen, Cheng-Yu Tsai, Kyle F. Nelson, Koichi S Kobayashi, Elliot Israel, Xiao Zhen Zhou, Linda K. Nicholson, Kun Ping Lu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Abstract Interleukin 33 (IL-33) is among the earliest-released cytokines in response to allergens that orchestrate type 2 immunity. The prolyl cis-trans isomerase PIN1 is known to induce cytokines for eosinophil survival and activation by stabilizing
Externí odkaz:
https://doaj.org/article/f59a26dd71a44b3c90785a69ce33bbf8
Autor:
Jorge Enrique Tovar Perez, Shilan Zhang, William Hodgeman, Sabeeta Kapoor, Praveen Rajendran, Koichi S. Kobayashi, Roderick H. Dashwood
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Gastrointestinal malignancies encompass a diverse group of cancers that pose significant challenges to global health. The major histocompatibility complex (MHC) plays a pivotal role in immune surveillance, orchestrating the recogn
Externí odkaz:
https://doaj.org/article/0e8b189a61454d52aa2a22e919c30eda
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
The human intestinal tract harbors large bacterial community consisting of commensal, symbiotic and pathogenic strains, which are constantly interacting with the intestinal immune system. This interaction elicits a non-pathological basal level of imm
Externí odkaz:
https://doaj.org/article/a45823758bf746d0b3da21f35ca45a73
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66914 (2013)
Helicobacter pylori (H. pylori) infects the gastric mucosa and persists for the life of the host. Bacterial persistence may be due to the induction of regulatory T cells (Tregs) whichmay have protective effects against other diseases such as asthma.
Externí odkaz:
https://doaj.org/article/2db7b38d7fad4ba1b736555546408d48
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39042 (2012)
Orientia tsutsugamushi, a causative agent of scrub typhus, is an obligate intracellular bacterium, which escapes from the endo/phagosome and replicates in the host cytoplasm. O. tsutsugamushi infection induces production of pro-inflammatory mediators
Externí odkaz:
https://doaj.org/article/35c1e3dbcf134260a5ca1e3288b8c688
Autor:
Tanja Petnicki-Ocwieja, Alicia S DeFrancesco, Erin Chung, Courtney T Darcy, Roderick T Bronson, Koichi S Kobayashi, Linden T Hu
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17414 (2011)
The internalization of Borrelia burgdorferi, the causative agent of Lyme disease, by phagocytes is essential for an effective activation of the immune response to this pathogen. The intracellular, cytosolic receptor Nod2 has been shown to play varyin
Externí odkaz:
https://doaj.org/article/5050b70fc2304470abf52e0b25696394
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11758 (2010)
The ehrlichiae are small gram-negative obligate intracellular bacteria in the family Anaplasmataceae. Ehrlichial infection in an accidental host may result in fatal diseases such as human monocytotropic ehrlichiosis, an emerging, tick-borne disease.
Externí odkaz:
https://doaj.org/article/9bc2a9f704d34bcdadfeaa5cbb5d1334
Autor:
Sunny Shin, Christopher L Case, Kristina A Archer, Catarina V Nogueira, Koichi S Kobayashi, Richard A Flavell, Craig R Roy, Dario S Zamboni
Publikováno v:
PLoS Pathogens, Vol 4, Iss 11, p e1000220 (2008)
The immune system must discriminate between pathogenic and nonpathogenic microbes in order to initiate an appropriate response. Toll-like receptors (TLRs) detect microbial components common to both pathogenic and nonpathogenic bacteria, whereas Nod-l
Externí odkaz:
https://doaj.org/article/29245ce7ebc443529b34c5387d22d544
Autor:
Julia Plocica, Fengguang Guo, Jugal Kishore Das, Koichi S. Kobayashi, Thomas A. Ficht, Robert C. Alaniz, Jianxun Song, Paul de Figueiredo
Publikováno v:
Journal of Translational Autoimmunity, Vol 6, Iss , Pp 100198- (2023)
Autoimmune diseases such as rheumatoid arthritis and type 1 diabetes are increasingly common global problems. Concerns about increases in the prevalence of such diseases and the limited efficacy of conventional treatment regimens necessitates new the
Externí odkaz:
https://doaj.org/article/8da82bd35dfb461283b54c870da9d9d2
Autor:
Jugal Kishore Das, Fengguang Guo, Carrie Hunt, Shelby Steinmeyer, Julia A Plocica, Koichi S. Kobayashi, Yufang Ding, Arul Jayaraman, Thomas A Ficht, Robert C. Alaniz, Paul de Figueiredo, Jianxun Song
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Immunotherapy has led to impressive advances in the treatment of autoimmune and pro-inflammatory disorders; yet, its clinical outcomes remain limited by a variety of factors including the pro-inflammatory microenvironment (IME). Discovering effective
Externí odkaz:
https://doaj.org/article/b23a1d9e8ee941c29942432317185d80