Zobrazeno 1 - 10
of 321
pro vyhledávání: '"Koichi Otani"'
Autor:
Makoto Ohba, Ryota Kobayashi, Chifumi Iseki, Kazukuni Kirii, Daichi Morioka, Koichi Otani, Yasuyuki Ohta, Yukihiko Sonoda, Koji Suzuki, Masafumi Kanoto
Publikováno v:
BMC Medical Imaging, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Cerebrospinal fluid (CSF) area mask correction reduces the influence of low [123I]-N-fluoropropyl-2b-carbomethoxy-3b-(4-iodophenyl) nortropane (123I-FP-CIT) accumulation in the volume of interest (VOI) by CSF area dilatation on th
Externí odkaz:
https://doaj.org/article/39c544a4918146588abae2923651cf38
Autor:
Ryota Kobayashi, Hiroya Naruse, Shinobu Kawakatsu, Chifumi Iseki, Yuya Suzuki, Shingo Koyama, Daichi Morioka, Hiroyuki Ishiura, Jun Mitsui, Yasuyuki Ohta, Shoji Tsuji, Tatsushi Toda, Koichi Otani
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Variants in the valosin-containing protein (VCP) gene were identified as one of the causes for inclusion body myopathy associated with Paget disease of the bone and frontotemporal dementia (FTD). Previously identified pathogenic v
Externí odkaz:
https://doaj.org/article/5741575af9914cad999707841c3cfa3c
Autor:
Fumika Sato, Akihito Suzuki, Keisuke Noto, Toshinori Shirata, Muneaki Kanno, Ryota Kobayashi, Koichi Otani
Publikováno v:
PCN Reports, Vol 1, Iss 3, Pp n/a-n/a (2022)
Abstract Background Serotonin syndrome is characterized by mental status changes, autonomic hyperactivity, and neuromuscular abnormalities. This syndrome results from various medications that engender serotonergic overactivity. Atomoxetine is a norep
Externí odkaz:
https://doaj.org/article/600e6597bac4417ca7646517f7492ac8
Autor:
Akihito Suzuki, Toshinori Shirata, Keisuke Noto, Yoshihiko Matsumoto, Haruka Muraosa, Mio Abe, Kaoru Goto, Koichi Otani
Publikováno v:
Brain and Behavior, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background The μ‐opioid receptor (MOR) plays an important role in social bonding behaviors, while it is implicated in the pathophysiology of depression. It is shown that the A118G polymorphism (rs1799971) of the MOR gene (OPRM1) causes am
Externí odkaz:
https://doaj.org/article/d49ac04a2a0e48fb9551b300604c0a7e
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 10, Iss 2, Pp 63-68 (2020)
Background: Easy Z-score imaging system (eZIS)-assisted SPECT accurately detects decreases in cerebral blood flow in the posterior cingulate cortex (PCC), precuneus, and parietal lobe, the cerebral regions deeply implicated in Alzheimer’s disease (
Externí odkaz:
https://doaj.org/article/58240c19724241ad86fd6bf8857c09b3
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
Apathy and depression are frequently observed as behavioral and psychological symptoms of dementia, respectively, and are important for ensuring adequate care. This study aims to explore effective non-pharmacological interventions for apathy and depr
Externí odkaz:
https://doaj.org/article/f5bba086018941dcaa2dcd10e3635645
Autor:
Ryota Kobayashi, Shinobu Kawakatsu, Makoto Ohba, Daichi Morioka, Masafumi Kanoto, Koichi Otani
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
IntroductionFrontotemporal lobar degeneration (FTLD) is a clinical syndrome with pathological heterogeneity, including Pick’s disease and trans-activating response region (TAR) DNA-binding protein with a molecular mass of 43 kDa (TDP-43) proteinopa
Externí odkaz:
https://doaj.org/article/bb783df8aa5340c79e8fa930397593b2
Autor:
Keisuke Noto, Akihito Suzuki, Toshinori Shirata, Yoshihiko Matsumoto, Haruka Muraosa, Kaoru Goto, Koichi Otani
Publikováno v:
Brain and Behavior, Vol 11, Iss 11, Pp n/a-n/a (2021)
Abstract Introduction Oxytocin receptor (OXTR) gene polymorphism reportedly moderates effects of negative environments during childhood on mental function and behavior such as depressive symptoms and externalizing problems. This study examined OXTR g
Externí odkaz:
https://doaj.org/article/7f705adb9fc94391895011f1295c0138
Autor:
Akihito Suzuki, Ryota Kobayashi, Toshinori Shirata, Hitomi Komoriya, Masafumi Kanoto, Koichi Otani
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Akathisia, which characterized by subjective restlessness and objective hyperactivity, is induced mostly by antipsychotics and antidepressants. Chronic akathisia is defined as persistence of symptoms for more than 3 months. The pathophysiology of chr
Externí odkaz:
https://doaj.org/article/71961d0236424c3780deeaa18248f207
Autor:
Ryota Kobayashi, Hiroshi Hayashi, Shinobu Kawakatsu, Aiko Ishiki, Nobuyuki Okamura, Hiroyuki Arai, Koichi Otani
Publikováno v:
BMC Neurology, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background Semantic variant primary progressive aphasia (svPPA) is a subtype of primary progressive aphasia characterized by two-way anomia and disturbance in word comprehension, with focal atrophy in the left temporal lobe. [18F]THK-5351 wa
Externí odkaz:
https://doaj.org/article/7fb77c4fe31049c194a637662d6e78ed