Výsledky vyhledávání - "Koichi Onishi"

Akademický článek

Optimal dose determination of enerisant (TS-091) for patients with narcolepsy: two randomized, double-blind, placebo-controlled trials

Autor: Yuichi Inoue, Makoto Uchiyama, Hideo Umeuchi, Koichi Onishi, Hiroki Ogo, Iwao Kitajima, Isao Matsushita, Izumi Nishino, Naohisa Uchimura

Publikováno v: BMC Psychiatry, Vol 22, Iss 1, Pp 1-13 (2022)

Abstract Background The histamine H3 receptor has emerged as one of the most promising targets of novel pharmacotherapy for narcolepsy. Studies now aim to investigate the optimal dose of enerisant, a novel H3 antagonist/inverse agonist, for the treat

Externí odkaz: https://doaj.org/article/f3a3df779f874d3d9705149079461ada

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Electric field and oxygen concentration-dependent transport properties of nano-graphene oxide

Autor: Yong Sun, Kenta Kirimoto, Hayami Hattori, Yuto Kitamura, Enda Fan, Koichi Onishi

Publikováno v: AIP Advances, Vol 9, Iss 9, Pp 095010-095010-7 (2019)

Electrical transport properties of the nano-graphene oxide were investigated by measuring current-voltage characteristics in the wide temperature range of 15 K∼450 K. The n-GO is composed of nanometer-sized intact graphene-like sp2 domains embedded

Externí odkaz: https://doaj.org/article/1ce14d355e3c4cd09bbbefad67429b0d

Zobrazit plný text záznamu

Akademický článek

Sliding-friction-dependent stress at the graphene/LiNbO3 interface around the critical temperature of the stress-free state

Autor: Yong Sun, Kenta Kirimoto, Hiroyuki Kamada, Koichi Onishi, Daichi Etoh, Shohei Yoshimura, Shigeru Kanemitsu

Publikováno v: AIP Advances, Vol 9, Iss 2, Pp 025316-025316-10 (2019)

The graphene/LiNbO3 structure exists in an interfacial stress-free state at the temperature at which the graphene was transferred onto the LiNbO3 substrate surface. Coupling of a surface acoustic wave with this structure revealed drastic changes in t

Externí odkaz: https://doaj.org/article/12d6a7bd32514a49a6a5103da35665e6

Zobrazit plný text záznamu

Akademický článek

Coupling behaviors of graphene/SiO2/Si structure with external electric field

Autor: Koichi Onishi, Kenta Kirimoto, Yong Sun

Publikováno v: AIP Advances, Vol 7, Iss 2, Pp 025113-025113-17 (2017)

A traveling electric field in surface acoustic wave was introduced into the graphene/SiO2/Si sample in the temperature range of 15 K to 300 K. The coupling behaviors between the sample and the electric field were analyzed using two parameters, the in

Externí odkaz: https://doaj.org/article/a13e5922bf3047e6b0bcf72b6f7c6734

Zobrazit plný text záznamu

Drug–drug interaction potential and clinical pharmacokinetics of enerisant, a novel potent and selective histamine H3 receptor antagonist

Autor: Koichi Onishi, Izumi Nishino, Iwao Kitajima, Yoko Mano, Shuichi Terasaka, Kenji Hachiuma, Hiromi Endo

Publikováno v: Xenobiotica. 51:786-795

We evaluated the in vitro drug–drug interaction (DDI) potential of enerisant (TS-091), a histamine H3 receptor antagonist/inverse agonist, mediated by cytochrome P450 (CYP) and transporters, as wel...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a75047e39e03c349602a283cc4c7b8c
https://doi.org/10.1080/00498254.2021.1918361

Zobrazit plný text záznamu

Plný text ve formátu HTML