Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Koichi Ogami"'
Autor:
Miho M. Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe, Tatsunori Nishimura, Fumiharu Ohka, Ryuta Saito, Shinya Sato, Junya Kobayashi, Ryoji Yao, Kanjiro Miyata, Kazunori Kataoka, Hiroshi I. Suzuki, Yutaka Kondo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Oncogene-induced DNA replication stress (RS) and consequent pathogenic R-loop formation are known to impede S phase progression. Nonetheless, cancer cells continuously proliferate under such high-stressed conditions through incompletely unde
Externí odkaz:
https://doaj.org/article/3a39adce796d43a99a5582287d10e0b2
Autor:
Hiroki Kitai, Noritoshi Kato, Koichi Ogami, Shintaro Komatsu, Yu Watanabe, Seiko Yoshino, Eri Koshi, Shoma Tsubota, Yoshio Funahashi, Takahiro Maeda, Kazuhiro Furuhashi, Takuji Ishimoto, Tomoki Kosugi, Shoichi Maruyama, Kenji Kadomatsu, Hiroshi I. Suzuki
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Combinatorial gene regulation by multiple microRNAs (miRNAs) is widespread and closely spaced target sites often act cooperatively to achieve stronger repression (“neighborhood” miRNA cotargeting). While miRNA cotarget sites a
Externí odkaz:
https://doaj.org/article/814489ea1fa84422a7415f8368b0e8b0
Autor:
Koichi Ogami, Keima Ogawa, Shoko Sanpei, Fumito Ichikawa, Tsuyoshi Udagawa, Shin-ichi Hoshino
Publikováno v:
Cells, Vol 12, Iss 19, p 2410 (2023)
During early embryonic development, the RNA-binding protein CPEB mediates cytoplasmic polyadenylation and translational activation through a combinatorial code defined by the cy-toplasmic polyadenylation element (CPE) present in maternal mRNAs. Howev
Externí odkaz:
https://doaj.org/article/ea2c3943050c45efb0e763bf695ab082
Autor:
Larry C. Cheng, Dinghai Zheng, Erdene Baljinnyam, Fangzheng Sun, Koichi Ogami, Percy Luk Yeung, Mainul Hoque, Chi-Wei Lu, James L. Manley, Bin Tian
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Alternative polyadenylation generates multiple mRNA isoforms with different 3′ UTR sizes. Here the authors report global 3′ UTR shortening that is coupled to increased expression of secretory pathway genes in secretory cell differentiation.
Externí odkaz:
https://doaj.org/article/930e44d8511440f79f4ea3c291ee5bb2
Autor:
Hiromasa Aoki, Misaki Yamashita, Tadahiro Hashita, Koichi Ogami, Shinichi Hoshino, Takahiro Iwao, Tamihide Matsunaga
Publikováno v:
Heliyon, Vol 6, Iss 3, Pp e03493- (2020)
Endothelial cells (ECs) and endothelial progenitor cells (EPCs) play crucial roles in maintaining vascular health and homeostasis. Both cell types have been used in regenerative therapy as well as in various in vitro models; however, the properties o
Externí odkaz:
https://doaj.org/article/e1244811c49543b890057454947623a1
Autor:
Koichi Ogami, Hiroshi I. Suzuki
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13401 (2021)
The genome is pervasively transcribed across various species, yielding numerous non-coding RNAs. As a counterbalance for pervasive transcription, various organisms have a nuclear RNA exosome complex, whose structure is well conserved between yeast an
Externí odkaz:
https://doaj.org/article/3d062b4aeb0d4ce28446efc7b1b83ebe
Autor:
Takuto Nogimori, Koichi Ogami, Yuka Oishi, Ryoya Goda, Nao Hosoda, Yoshiaki Kitamura, Yukio Kitade, Shin-ichi Hoshino
Publikováno v:
Viruses, Vol 12, Iss 2, p 174 (2020)
The 2′-5′-oligoadenylate synthetase (OAS)/RNase L system protects hosts against pathogenic viruses through cleavage of the exogenous single-stranded RNA. In this system, an evolutionally conserved RNA quality control factor Dom34 (known as Pelota
Externí odkaz:
https://doaj.org/article/838ee9f5587e44f2bdccdbf020a55f99
Publikováno v:
Non-Coding RNA, Vol 4, Iss 1, p 8 (2018)
The nuclear RNA exosome is an essential and versatile machinery that regulates maturation and degradation of a huge plethora of RNA species. The past two decades have witnessed remarkable progress in understanding the whole picture of its RNA substra
Externí odkaz:
https://doaj.org/article/958311400efb4666ae751e4b40907484
Publikováno v:
STAR Protocols. 4:102340
Autor:
Koichi Ogami, Yuka Oishi, Kentaro Sakamoto, Mayu Okumura, Ryota Yamagishi, Takumi Inoue, Masaya Hibino, Takuto Nogimori, Natsumi Yamaguchi, Kazuya Furutachi, Nao Hosoda, Hiroto Inagaki, Shin-ichi Hoshino
Publikováno v:
Cell Reports. 41:111548
Translation of 5' terminal oligopyrimidine (TOP) mRNAs encoding the protein synthesis machinery is strictly regulated by an amino-acid-sensing mTOR pathway. However, its regulatory mechanism remains elusive. Here, we demonstrate that TOP mRNA transla