Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Koichi Nakamaru"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 3, Pp 307-313 (2004)
A number of experimental models of colitis have been proposed. However, few studies have presented T helper-2 (Th-2) type colitis models that substitute for human ulcerative colitis (UC). In recent years, the murine oxazolone (OXA)-induced colitis mo
Externí odkaz:
https://doaj.org/article/66b5f6c0b5544fb69cbbcd86c4dbc416
Autor:
Mamoru Watanabe, Shin Makita, Koichi Nakamaru, Nagamu Inoue, Hiromasa Ishii, Yasushi Iwao, Masashi Kurimoto, Motomi Yamazaki, Ryuichi Okamoto, Koji Uraushihara, M. Ikeda, Haruhiko Ogata, Toshifumi Hibi, Toshiro Sato, Akira Okazawa, Takanori Kanai, Takahiro Kawamura
Publikováno v:
Clinical and Experimental Immunology. 136:269-276
SUMMARYIntestinal epithelial cell (IEC)-derived cytokines, such as stem cell factor (SCF), interleukin (IL)-7 and IL-15 are known to be required for the development of intestinal intraepithelial lymphocytes (IELs). A newly described cytokine, IL-18,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dc04409070bbddfc48be5355df635d
https://doi.org/10.1111/j.1365-2249.2004.02431.x
https://doi.org/10.1111/j.1365-2249.2004.02431.x
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 3, Pp 307-313 (2004)
A number of experimental models of colitis have been proposed. However, few studies have presented T helper-2 (Th-2) type colitis models that substitute for human ulcerative colitis (UC). In recent years, the murine oxazolone (OXA)-induced colitis mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d05f28697ff7a0b8fffd6b04dabe2ee
https://doi.org/10.1254/jphs.fp0040214
https://doi.org/10.1254/jphs.fp0040214
Autor:
Toshiji Sugai, Nobuhiro Kinoshita, Shigeo Kawase, Masako Sato, Koichi Nakamaru, Sugure Taniguchi
Publikováno v:
Folia Pharmacologica Japonica. 104:447-457
Mesalazine microgranules (Pentasa) were developed as a drug for idiopathic inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. In this study, we examined the effect of mesalazine on radical scavenging, lipid peroxidation and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f71d102100edcdc6d2df9a7303b5911
https://doi.org/10.1254/fpj.104.447
https://doi.org/10.1254/fpj.104.447
Autor:
Makoto Naganuma, Mamoru Watanabe, Makiyo Okamoto, Toshifumi Hibi, Masao Ikeda, Takanori Kanai, Hiromasa Ishii, Akira Okazawa, Koichi Nakamaru, Masashi Kurimoto
Publikováno v:
Gastroenterology. 119(6)
Background & Aims: Crohn's disease (CD) is characterized by a marked accumulation of activated Th1 type CD4 + T cells and macrophages in inflamed intestinal mucosa. Interleukin (IL)-18 is a recently described cytokine that mainly exists in activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f1fa80b186af93f422bc6a05b0dced
https://pubmed.ncbi.nlm.nih.gov/11113073
https://pubmed.ncbi.nlm.nih.gov/11113073
Autor:
Takayuki Hongyo, Shigeo Kawase, Toshiji Sugai, Yukio Tanaka, Sugure Taniguchi, Koichi Nakamaru, Masako Sato
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 104(4)
Mesalazine microgranules are an ethylcellulose-coated formulation from which mesalazine is released throughout the intestinal tract and are expected to be effective for idiopathic inflammatory bowel disease, ulcerative colitis and Crohn's disease. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4525e6bf621fce6029ae1b1d1f840cb1
https://pubmed.ncbi.nlm.nih.gov/7959421
https://pubmed.ncbi.nlm.nih.gov/7959421
Autor:
Susumu Okamoto, Koichi Nakamaru, Toshifumi Hibi, Tomoharu Yajima, Hiromasa Ishii, Takanori Kanai, Masaru Nakano, Kazuto Fukui, Motomi Yamazaki, Mamoru Watanabe
Publikováno v:
Gastroenterology. 118:A112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab672eaba35d4cdd76c1d16c0f39b6b
https://doi.org/10.1016/s0016-5085(00)82527-5
https://doi.org/10.1016/s0016-5085(00)82527-5
Autor:
Mamoru Watanabe, Susumu Okamoto, Toshifumi Hibi, Motomi Yamazaki, Takanori Kanai, Masaru Nakano, Koichi Nakamaru, Kazuto Fukui, Nagamu Inoue
Publikováno v:
Gastroenterology. 118:A1376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b74535fc4e1c85c5baa30b5cc53f5fe
https://doi.org/10.1016/s0016-5085(00)81379-7
https://doi.org/10.1016/s0016-5085(00)81379-7
Publikováno v:
Japanese Journal of Pharmacology. 64:314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ecc5cbc989ac583e0cf623438db3bb
https://doi.org/10.1016/s0021-5198(19)50888-5
https://doi.org/10.1016/s0021-5198(19)50888-5
Autor:
Nobuyuki Nagata, Kazuhiro Hirabayashi, Kazuo Watanabe, Takeo Mori, Midori Takeda, Shoji Shibata, Kunio Takahashi, Masatoshi Harada, Yoshifumi Hatakeyama, Koichi Nakamaru, Shingo Yano
Publikováno v:
Chemical and Pharmaceutical Bulletin. 37:2500-2504
Glycyrrhetinic acid (Ia) and eighteen related derivatives were examined for antiulcer activity using stress-induced gastric lesions (restraint plus water immersion at 25 degrees C) in mice and rats as screening tests. Among the compounds tested, dihe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11867581722da8dd8308051c944a7354
https://doi.org/10.1248/cpb.37.2500
https://doi.org/10.1248/cpb.37.2500