Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Koichi Metori"'
Autor:
Yoshinori Onuki, Yoshihisa Yamamoto, Toshiro Fukami, Toyofumi Suzuki, Koichi Metori, Tatsuo Koide
Publikováno v:
Vibrational Spectroscopy. 93:17-22
The purpose of this study is to verify the usefulness of near infrared (NIR) spectroscopy for evaluation of pharmaceutical properties of cream formulations. The present study examined in detail the pharmaceutical properties of clobetasol propionate (
Autor:
Taketo Uchiyama, Hiroaki Saito, Keiichi Tabata, Yoshimi Ichimaru, Shinichi Miyairi, Koichi Metori, Takashi Suzuki
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1403-1406
Indirubin is a potent inhibitor of cell cycle-related protein kinases by binding to the ATP-binding site and thus is a promising compound for development as an antitumor drug. We prepared indirubin 3′-(O-oxiran-2-ylmethyl)oxime (Epox/Ind), in which
Autor:
Makoto Fukatsu, Yumiko Kimura, Etsuyo Kaneko, Norihiro Banno, Koichi Metori, Toshihiro Akihisa, Ken-ichi Seino, Shun Tochizawa, Kensuke Watanabe
Publikováno v:
Journal of Oleo Science. 59:49-57
A new iridoid glycoside, 9-epi-6alpha-methoxy geniposidic acid (4), three new hemiterpene glycosides, 3-methylbut-3-enyl 2'-O-(beta-D-glucopyranosyl)-beta-D-glucopyranoside (nonioside K) (6), 3-methylbut-3-enyl 6'-O-(beta-D-xylopyranosyl)-beta-D-gluc
Publikováno v:
Journal of Heterocyclic Chemistry. 45:383-387
A novel water-soluble N-methyl-D-aspartate (NMDA) receptor antagonist ATGDMAP 1 as synthesized and the effect of 1 on NMDA receptors was studied using voltage-clamp recordings of recombinant NMDA receptors expressed in Xenopus oocytes. The compound 1
Autor:
Yumiko Kimura, Kentaro Yamaguchi, Muneharu Miyake, Koichi Metori, Yoshihisa Sei, Tomoyuki Ozawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 53:1029-1033
The investigation of the host-guest complex formations between cyclophane (TGDMAP) (1) as a host and L-acidic amino acids such as L-glutamic acid (Glu) and L-aspartic acid (Asp) as guests was carried out using fast atom bombardment (FAB), electrospra
Autor:
Harukuni Tokuda, Masakazu Ogata, Koichi Metori, Toshihiro Akihisa, Takashi Suzuki, Naoto Shimizu, Hoyoku Nishino, Motohiko Ukiya, Masao Iizuka
Publikováno v:
Cancer Letters. 205:9-13
The inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter, 12- O -tetradecanoylphorbol-13-acetate (TPA), in Raji cells as a primary screening test for anti-tumor promoters, for 22 fatty acids (as fre
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 51:566-569
By 1H NMR spectrometry it is impossible to confirm the association constant (Ks) of the host-guest complex which peaks of guest become broad and overlapped by host peaks. In order to solve the obstacles and raise the usefulness of FAB mass spectromet
Publikováno v:
Biological and Pharmaceutical Bulletin. 21:1306-1310
We have reported that collagen synthesis was stimulated by the administration of a hot water extract from the leaves of Eucommia ulmoides OLIVER, Eucommiaceae (Du-Zhong leaves) in false aged model rats. In this paper, we set out to examine the compou
Autor:
Yumiko Kimura, Ken Yasukawa, Masaaki Tagata, Toshihiro Akihisa, Tsunetomo Matsuzawa, Scott G. Franzblau, Motohiko Ukiya, Harukuni Tokuda, Koichi Metori, Takashi Suzuki
Publikováno v:
Biological and Pharmaceutical Bulletin. 28:1117-1119
Seven sterols (1-7) and eight polyisoprenepolyols (8-15), isolated from the non-saponifiable lipid fraction of the dichloromethane extract of an edible mushroom, Hypsizigus marmoreus (Buna-shimeji), were tested for their antitubercular activity again
Autor:
Yoshinori Onuki, Tatsuo Koide, Noriko Katori, Toyofumi Suzuki, Koichi Metori, Kazuo Tomono, Yoshihisa Yamamoto, Yukio Hiyama, Toshiro Fukami
Publikováno v:
International journal of pharmaceutics. 463(1)
In the present study, we performed comprehensive pharmaceutical evaluation among an original clobetasone butyrate (CLB) ointment product and three generic products. Although spherocrystal images were observed under a polarizing microscope for only Ki