Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Koichi Kuromi"'
Publikováno v:
Drug Development and Industrial Pharmacy. 48:239-246
R-α-lipoic acid (RLA) and dihydrolipoic acid (DHLA), a reduced form of RLA, are potent endogenous antioxidants that can reduce oxidative damage. Despite their numerous nutraceutical potentials, clinical applications of RLA are still limited due to i
Autor:
Antara Ghosh, Sujan Banik, Yui Suzuki, Yasuhiko Mibe, Shingo Rikimura, Tomomi Komamoto, Koichi Kuromi, Kohei Yamada, Hideyuki Sato, Satomi Onoue
Publikováno v:
Journal of the science of food and agricultureREFERENCES.
The present study was aimed to develop astaxanthin (AX)-loaded liposomes by the utilization of soybean phosphatidylcholine (PC) and lysophosphatidylcholine (LPC) to improve the nutraceutical properties of AX. AX-loaded liposomes consisting of PC (PC/
Autor:
Atsuko Fujiwara, Masatoshi Yamamoto, Kazuhiro Owada, Nobuyuki Suzuki, Chie Ueno, Koichi Kuromi, Mitsuko Kamimura, Naohisa Ogo, Kumiko Mizuno, Hiroyuki Kurita
Publikováno v:
Journal of Health Science. 54:310-314
Using chiral liquid chromatography-mass spectrometry (LC/MS), a simple and rapid identification test was developed for aminotadalafil [(6R,12aR)-2-amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Autor:
Kumiko Mizuno, Hiroyuki Kurita, Mitsuko Kamimura, Kazuhiro Owada, Koichi Kuromi, Masatoshi Yamamoto, Chie Ueno
Publikováno v:
Journal of Society of Cosmetic Chemists of Japan. 42:36-39
ガスクロマトグラフィー (GC) による練り歯磨き中のジエチレングリコール (DEG) の迅速かつ簡易な分析法を開発した。練り歯磨き中のDEGは, 1, 4-ブタンジオールを内標準物質として含有す
Publikováno v:
Journal of Liposome Research. 13:25-27
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:1385-1387
A novel anti-tumor agent, 6-[[2-(dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride (TAS-103), effectively inhibits both topoisomerase I and II activities. To enhance anti-tumor efficacy and to reduce the side effects
Autor:
Koichi Kuromi, Kumiko Mizuno, Mitsuko Kamimura, Masatoshi Yamamoto, Kazuhiro Owada, Chie Ueno, Atsuko Fujiwara, Hiroyuki Kurita
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 128(3)
A simple and rapid method for screening of drugs in health foods using 2-dimensional TLC was established. The development systems were: (1) ethyl acetate/methanol/28% ammonia (85:10:5), (2) cyclohexane/toluene/diethyl amine (65:25:10), (3) methanol a
Publikováno v:
Biologicalpharmaceutical bulletin. 25(10)
A novel anti-tumor agent, 6-[[2-(dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride (TAS-103), effectively inhibits both topoisomerase I and II activities. To enhance anti-tumor efficacy and to reduce the side effects
Autor:
Naoto Oku, Hideto Fukatsu, Koichi Kuromi, Koichi Ogino, Takao Taki, Tomohiro Asai, Michinori Tanaka
Publikováno v:
Biologicalpharmaceutical bulletin. 25(7)
Novel peptides homing to angiogenic vessels were recently isolated from a phage-displayed random pentade-capeptide library, and peptides having WRP sequence showed tumor growth suppression. In this study, we observed that another novel sequence, PVVL
Autor:
Koichi Kuromi, Masami Kondo, Kosuke Shimizu, Koichi Ogino, Akira Matsuda, Takao Taki, Naoto Oku, Tomohiro Asai, Koh Watanabe, Satoshi Shuto
Publikováno v:
FEBS letters. 520(1-3)
We previously reported that liposomalized 5′-O-dipalmitoylphosphatidyl 2′-C-cyano-2′-deoxy-1-β-D-arabino-pentofuranosylcytosine (DPP-CNDAC), a hydrophobized derivative of the novel antitumor nucleoside CNDAC, is quite useful for cancer therapy