Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Koichi Ikizawa"'
Autor:
Yuki Tanaka, Hiroshi Wada, Risa Goto, Toshihiro Osada, Keisuke Yamamura, Satoshi Fukaya, Atsushi Shimizu, Mitsuru Okubo, Kazuhisa Minamiguchi, Koichi Ikizawa, Eiji Sasaki, Teruhiro Utsugi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/badb391e12ce4c1c9c405c0223cc10d0
Autor:
Yukiyoshi Yanagihara, Keiichi Kajiwara, Yuji Basaki, Koichi Ikizawa, Miyuki Mori, Kazuo Akiyama, Nobuaki Kawamura, Yukio Sakiyama
Publikováno v:
Allergology International, Vol 49, Iss 3, Pp 195-204 (2000)
We have previously reported that an adenosine deaminase (ADA)-deficient patient treated with T cell-directed gene therapy had an increase in serum IgE levels, despite a marked inversion of the CD4/CD8 ratio. In the present report, we have analyzed th
Externí odkaz:
https://doaj.org/article/6358bf5a9bbe44de880f1bcd7f24f901
Autor:
Teruhiro Utsugi, Mitsuru Okubo, Atsushi Shimizu, Toshihiro Osada, Satoshi Fukaya, Keisuke Yamamura, Yuki Tanaka, Hiroshi Wada, Eiji Sasaki, Risa Goto, Koichi Ikizawa, Kazuhisa Minamiguchi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Cancer peptide vaccines are a promising cancer immunotherapy that can induce cancer-specific cytotoxic T lymphocytes (CTLs) in tumors. However, recent clinical trials of cancer vaccines have revealed that the efficacy of the vaccines is limited. Targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3114c969f6be9a9500948960b132bcba
http://europepmc.org/articles/PMC7560884
http://europepmc.org/articles/PMC7560884
Autor:
Teruhiro Utsugi, Fumihito Hosoi, Kenji F. Tanaka, Daichi Akasaka, Akihiro Saito, Ryusuke Kaneko, Naruto Noma, Yohei Yoshiga, Satoru Iguchi, Koichi Ikizawa, Yasunobu Arima
Publikováno v:
Poster Presentations.
Background Bone erosions and cartilage damages are a pathological hallmark of rheumatoid arthritis (RA) and are associated with poor functional outcome1. Aberrant activations of osteoclasts induced by receptor activator of nuclear factor κB ligand (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6110ee5767c068d0baf891a1641527ba
https://doi.org/10.1136/annrheumdis-2019-eular.2019
https://doi.org/10.1136/annrheumdis-2019-eular.2019
Autor:
Risa Goto, Satoshi Fukaya, Koichi Ikizawa, Hiroshi Wada, Toshihiro Osada, Nobuyuki Oda, Akira Gomori, Motomu Sakuragi, Naomoto Harada
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(1)
We generated a series of monochain HLA class I knock-in (KI) mouse strains, in which a chimeric HLA class I molecule (α1/α2 domain of HLA-A*0201, HLA-A*0301, HLA-A*2402, or HLA-A*3101 and α3 domain of H-2Db) was covalently linked with 15 aa to hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bebe9499b55898638da9ce464a8ea6e
https://pubmed.ncbi.nlm.nih.gov/27881704
https://pubmed.ncbi.nlm.nih.gov/27881704
Publikováno v:
Nature Immunology. 6:65-72
Signaling through the T cell antigen receptor leading to elimination (negative selection) or differentiation (positive selection) of developing thymocytes generates a self-tolerant T cell repertoire. Here we report that the serine-threonine kinase MI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f228788ad255772a17528f034db248d9
https://doi.org/10.1038/ni1145
https://doi.org/10.1038/ni1145
Autor:
Hideki Nagase, Mamoru Kiniwa, Katsunao Tanaka, Kiyoshi Tanigawa, Koichi Ikizawa, Hidekazu Miyake
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:1619-1622
The glucocorticoid receptor regulates gene expression mainly by two mechanisms; transactivation and trans-repression. A ligand with strong transrepression and weak transactivation activity is predicted to be a beneficial agent with potent anti-inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a12b00c65a0213a22863ffdb9797713
https://doi.org/10.1248/bpb.25.1619
https://doi.org/10.1248/bpb.25.1619
Autor:
Kiyoshi Tanigawa, Katsunao Tanaka, Mamoru Kiniwa, Hidetaka Nagase, Koichi Ikizawa, Hidekazu Miyake
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:1115-1118
Glucocorticoid regulates various physiological processes via the activation and repression of gene expression. The anti-inflammatory effects and the adverse effects are believed to be dependent on the repression and the activation of genes, respectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1056271c7f9141a8357f6dbef319857e
https://doi.org/10.1248/bpb.25.1115
https://doi.org/10.1248/bpb.25.1115
Autor:
Miyuki Mori, Nobuaki Kawamura, Kazuo Akiyama, Yukio Sakiyama, Koichi Ikizawa, Yukiyoshi Yanagihara, Keiichi Kajiwara, Yuji Basaki
Publikováno v:
Allergology International, Vol 49, Iss 3, Pp 195-204 (2000)
We have previously reported that an adenosine deaminase (ADA)-deficient patient treated with T cell-directed gene therapy had an increase in serum IgE levels, despite a marked inversion of the CD4/CD8 ratio. In the present report, we have analyzed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3c8a79e388b998cf7d0730d8f3fc50
https://doi.org/10.1046/j.1440-1592.2000.00176.x
https://doi.org/10.1046/j.1440-1592.2000.00176.x
Autor:
H. Yamaya, Y. Basaki, M. Kojima, Hiroichi Nagai, K. Sawada, M. Kiniwa, M. Watanabe, N. Matsuura, Koichi Ikizawa
Publikováno v:
Clinical & Experimental Allergy. 27:225-231
Summary Background Exposure of atopic patients to a specific allergen evokes an immediate response which is followed, in many cases, by a late phase reaction (LPR) some hours later. Here we have examined the immunological mechanisms required for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02d39d697de22cebe97aabf2fa3ffe1a
https://doi.org/10.1111/j.1365-2222.1997.tb00697.x
https://doi.org/10.1111/j.1365-2222.1997.tb00697.x