Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Koichi, Matsuzaki"'
Autor:
Naohiro Nakamura, Katsunori Yoshida, Rinako Tsuda, Miki Murata, Takashi Yamaguchi, Kanehiko Suwa, Mayuko Ichimura, Koichi Tsuneyama, Koichi Matsuzaki, Toshiaki Nakano, Junko Hirohara, Toshihito Seki, Kazuichi Okazaki, M. Eric Gershwin, Makoto Naganuma
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 12, Pp 1480-1492 (2021)
Introduction: Patients with primary biliary cholangitis (PBC) are at increased risk for development of hepatocellular carcinoma (HCC), particularly in the presence of comorbidities such as excessive alcohol consumption. Although liver fibrosis is an
Externí odkaz:
https://doaj.org/article/a7d28af6620d46afae51be927094cde5
Autor:
Kazuichi Okazaki, Jun-ichi Fujisawa, Shigeru Taketani, Toshihito Seki, Yoshiko Uemura, Katsunori Yoshida, Go Sekimoto, Miki Murata, Chiaki Kitano, Koichi Matsuzaki
Supplementary Table 1, Figures 1-8 from Smad2 and Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions Transmit Malignant TGF-β Signal in Later Stages of Human Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc44a134c3794d1eac59c9bbf1df461c
https://doi.org/10.1158/0008-5472.22378715
https://doi.org/10.1158/0008-5472.22378715
Autor:
Kazuichi Okazaki, Jun-ichi Fujisawa, Hirofumi Matsui, Toshihito Seki, Miki Murata, Shigeo Mori, Katsunori Yoshida, Koichi Matsuzaki, Go Sekimoto
Supplementary Figure 1 from Reversible Smad-Dependent Signaling between Tumor Suppression and Oncogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8c50d617667c841bfc0b4c6a2b1d19
https://doi.org/10.1158/0008-5472.22368354
https://doi.org/10.1158/0008-5472.22368354
Autor:
Kazuichi Okazaki, Jun-ichi Fujisawa, Hirofumi Matsui, Toshihito Seki, Miki Murata, Shigeo Mori, Katsunori Yoshida, Koichi Matsuzaki, Go Sekimoto
Cancer cells often gain advantage by reducing the tumor-suppressive activity of transforming growth factor-β (TGF-β) together with stimulation of its oncogenic activity as in Ras-transformed cells; however, molecular mechanisms remain largely unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1751143527cf0bc29a8299f71c95a237
https://doi.org/10.1158/0008-5472.c.6495927
https://doi.org/10.1158/0008-5472.c.6495927
Autor:
Makoto Naganuma, M. Eric Gershwin, Kazuichi Okazaki, Toshihito Seki, Junko Hirohara, Toshiaki Nakano, Koichi Matsuzaki, Koichi Tsuneyama, Mayuko Ichimura, Kanehiko Suwa, Takashi Yamaguchi, Miki Murata, Rinako Tsuda, Katsunori Yoshida, Naohiro Nakamura
Publikováno v:
Frontiers in Bioscience-Landmark. 26(12):1480-1492
Introduction: Patients with primary biliary cholangitis (PBC) are at increased risk for development of hepatocellular carcinoma (HCC), particularly in the presence of comorbidities such as excessive alcohol consumption. Although liver fibrosis is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d730309b16c06c56be307a9bb3bcffec
http://repo.lib.tokushima-u.ac.jp/116737
http://repo.lib.tokushima-u.ac.jp/116737
Autor:
Koichi Matsuzaki, Takashi Yamaguchi, Tsukasa Ikeura, Katsunori Yoshida, Yuichi Hori, Mitsuaki Ishida, Kazuichi Okazaki, Sohei Satoi
Publikováno v:
Hepatobiliary & Pancreatic Diseases International. 19:581-589
Malignant intraductal papillary mucinous neoplasm (IPMN) has poor prognosis. The carcinogenesis of IPMN is not clear. The aim of this study was to clarify transitions in phosphorylated Smad3 signaling during IPMN carcinogenesis.By using immunohistoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0e8fb1408b8c86a64064228092fdc7
https://doi.org/10.1016/j.hbpd.2020.05.007
https://doi.org/10.1016/j.hbpd.2020.05.007
Autor:
Takashi Yamaguchi, Katsunori Yoshida, Miki Murata, Kanehiko Suwa, Koichi Tsuneyama, Koichi Matsuzaki, Makoto Naganuma
Publikováno v:
International Journal of Molecular Sciences. 23:6270
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis with insulin resistance, oxidative stress, lipotoxicity, adipokine secretion by fat cells, endotoxins (lipopolysaccharides) released by gut microbiota, and endoplasmic ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caa30d85f544e13e21f665cb7fa420e
https://doi.org/10.3390/ijms23116270
https://doi.org/10.3390/ijms23116270
Autor:
Koichi Matsuzaki, Toshiro Fukui, Ryo Suzuki, Yutaku Sakaguchi, Masayuki Sakao, Kazushige Uchida, Kazuichi Okazaki, Akiyoshi Nishio, Yu Takahashi, Masanobu Kishimoto
Publikováno v:
Pancreas. 46:605-613
Objectives The aims of this study are to characterize cell proliferation and differentiation during regeneration after pancreatitis and pancreatic buds during development to evaluate the role of Smad2/3, phosphorylated at the specific linker threonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f76ae2b7de09ab71fcf2a50975c862
https://doi.org/10.1097/mpa.0000000000000759
https://doi.org/10.1097/mpa.0000000000000759
Autor:
Ryo Suzuki, Akiyoshi Nishio, Toshiro Fukui, Yutaku Sakaguchi, Toshiyuki Mitsuyama, Koichi Matsuzaki, Masanobu Kishimoto, Kimi Sumimoto, Katsunori Yoshida, Masayuki Sakao, Takashi Okazaki, Kazushige Uchida, Yu Takahashi, Kazuichi Okazaki
Publikováno v:
Diseases of the Esophagus. 29:1-8
SummaryThe stem cell compartment in the esophageal epithelium is possibly located in the basal layer. We have identified significant expression of Smad2/3, phosphorylated at specific linker threonine residues (pSmad2/3L-Thr), in the epithelial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5de612c10bde997609c966957b99c43
https://doi.org/10.1111/dote.12277
https://doi.org/10.1111/dote.12277
Autor:
Koichi Matsuzaki, Takashi Yamaguchi, Rinako Kawamura, Yoshiko Uemura, Ryosuke Inokuchi, Chika Miyasaka, Toshihito Seki, Kazuichi Okazaki, Miki Murata, Yuutaku Sakaguchi, Yorika Nakano
Publikováno v:
Oncology Letters
Sorafenib is a multikinase inhibitor currently approved in Japan for the treatment of unresectable hepatocellular carcinoma. Interstitial pneumonia induced by sorafenib may have a fatal outcome, and therefore, has recently been the focus of many stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863ad7346e04ef8b1a9e6fdccc21743d
http://europepmc.org/articles/PMC4356407
http://europepmc.org/articles/PMC4356407