Výsledky vyhledávání - "Kohtaro Taniyama"

Akademický článek

Presence of GABAB Receptors Forming Heterodimers With GABAB1 and GABAB2 Subunits in Human Lower Esophageal Sphincter

Autor: Yasuhiro Torashima, Yasuhito Uezono, Masato Kanaide, Yuko Ando, Akihito Enjoji, Takashi Kanematsu, Kohtaro Taniyama

Publikováno v: Journal of Pharmacological Sciences, Vol 111, Iss 3, Pp 253-259 (2009)

Baclofen, a GABAB-receptor (GABABR) agonist has been proposed to be useful as therapeutic agent for the management of gastro-esophageal reflux disease, but whether the compound acts directly at the lower esophageal sphincter (LES) remains to be eluci

Externí odkaz: https://doaj.org/article/35df596bf8784dd68fed5edd7e38e92a

Zobrazit plný text záznamu

Akademický článek

μ-Opioid Receptor Forms a Functional Heterodimer With Cannabinoid CB1 Receptor: Electrophysiological and FRET Assay Analysis

Autor: Minoru Hojo, Yuka Sudo, Yuko Ando, Koichiro Minami, Masafumi Takada, Takehiro Matsubara, Masato Kanaide, Kohtaro Taniyama, Koji Sumikawa, Yasuhito Uezono

Publikováno v: Journal of Pharmacological Sciences, Vol 108, Iss 3, Pp 308-319 (2008)

Interactions between μ-opioid receptor (μOR) and cannabinoid CB1 receptor (CB1R) were examined by morphological and electrophysiological methods. In baby hamster kidney (BHK) cells coexpressing μOR fused to the yellow fluorescent protein Venus and

Externí odkaz: https://doaj.org/article/7f9b43ef082e44369f28bb9230d63d00

Zobrazit plný text záznamu

Akademický článek

Characterization of GABAB Receptors Involved in Inhibition of Motility Associated With Acetylcholine Release in the Dog Small Intestine: Possible Existence of a Heterodimer of GABAB1 and GABAB2 Subunits

Autor: Shunsuke Kawakami, Yasuhito Uezono, Noriaki Makimoto, Akihito Enjoji, Muneshige Kaibara, Takashi Kanematsu, Kohtaro Taniyama

Publikováno v: Journal of Pharmacological Sciences, Vol 94, Iss 4, Pp 368-375 (2004)

Characterization of the γ-aminobutyric acid (GABA)B receptor involved in the motility of dog small intestine was analyzed by application of the microdialysis method to the small intestine of the whole body of the dog. The reverse transcription-polym

Externí odkaz: https://doaj.org/article/b8d21d72d83a491e8046048362f4d2b2

Zobrazit plný text záznamu

Akademický článek

Increases in Serum Nitrite and Nitrate of a Few-Fold Adversely Affect the Outcome of Pregnancy in Rats

Autor: Tsuneo Inoue, Muneshige Kaibara, Yasuko Sakurai-Yamashita, Masahiro Kawano, Tadayuki Ishimaru, Kohtaro Taniyama

Publikováno v: Journal of Pharmacological Sciences, Vol 95, Iss 2, Pp 228-233 (2004)

The objective of this study was to evaluate serum nitrite and nitrate (nitrite/nitrate) concentrations that affect adversely pregnancy outcome. Pregnant rats, from day 2 to day 8 of pregnancy, were daily given subcutaneously several doses (5, 10, and

Externí odkaz: https://doaj.org/article/a92b18c23f5d4bc187f30e719168ad19

Zobrazit plný text záznamu

Akademický článek

Characterization of GABAB Receptor in the Human Colon

Autor: Yasuhito Uezono, Muneshige Kaibara, Hideki Hayashi, Shunsuke Kawakami, Akihito Enjoji, Takashi Kanematsu, Kohtaro Taniyama

Publikováno v: Journal of Pharmacological Sciences, Vol 94, Iss 2, Pp 211-213 (2004)

Characterization of the GABAB receptor in the human colon was performed by the reverse transcription-polymerase chain reaction (RT-PCR). mRNAs for both subunits of the GABAB receptor, GABAB1 and GABAB2, were detected in the human colon. The GABAB1(e)

Externí odkaz: https://doaj.org/article/9415f36672c7423cbfcda8afca8b6e66

Zobrazit plný text záznamu

Akademický článek

Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators.

Autor: Hideki Hayashi, Michael Cuddy, Vincent Chih-Wen Shu, Kenneth W Yip, Charitha Madiraju, Paul Diaz, Toshifumi Matsuyama, Muneshige Kaibara, Kohtaro Taniyama, Stefan Vasile, Eduard Sergienko, John C Reed

Publikováno v: PLoS ONE, Vol 4, Iss 10, p e7655 (2009)

BACKGROUND:Intracellular proteases constitute a class of promising drug discovery targets. Methods for high throughput screening against these targets are generally limited to in vitro biochemical assays that can suffer many technical limitations, as

Externí odkaz: https://doaj.org/article/5b9488d15bce43afa73b48d728cc9f99

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání