Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Kohtaro Takei"'
Autor:
Takuya Ikeda, Keita Takahashi, Minatsu Higashi, Hiroyasu Komiya, Tetsuya Asano, Akihiro Ogasawara, Shun Kubota, Shunta Hashiguchi, Misako Kunii, Kenichi Tanaka, Mikiko Tada, Hiroshi Doi, Hideyuki Takeuchi, Kohtaro Takei, Fumiaki Tanaka
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Nogo–Nogo receptor 1 (NgR1) signaling is significantly implicated in neurodegeneration in amyotrophic lateral sclerosis (ALS). We previously showed that lateral olfactory tract usher substance (LOTUS) is an endogenous antagonist of NgR1 th
Externí odkaz:
https://doaj.org/article/6bc952e6666947de89b52f8fcf5a7f1c
Publikováno v:
Cells, Vol 13, Iss 16, p 1369 (2024)
Neurite outgrowth is a crucial process for organizing neuronal circuits in neuronal development and regeneration after injury. Regenerative failure in the adult mammalian central nervous system (CNS) is attributed to axonal growth inhibitors such as
Externí odkaz:
https://doaj.org/article/21a53092765d49f1829a0cfabe8cb85a
Autor:
Yuki Kawaguchi, Junpei Matsubayashi, Yutaka Kawakami, Ryohei Nishida, Yuji Kurihara, Kohtaro Takei
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-13 (2022)
Abstract Background Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide but has no effective treatment. Amyloid beta (Aβ) protein, a primary risk factor for AD, accumulates and aggregates in the brain of patients with A
Externí odkaz:
https://doaj.org/article/48f01a0cce6b4ca8bd522ad02c01bcd8
Autor:
Ryohei Nishida, Yuki Kawaguchi, Junpei Matsubayashi, Rie Ishikawa, Satoshi Kida, Kohtaro Takei
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The Nogo signal is involved in impairment of memory formation. We previously reported the lateral olfactory tract usher substance (LOTUS) as an endogenous antagonist of the Nogo receptor 1 that mediates the inhibition of axon growth and syna
Externí odkaz:
https://doaj.org/article/6aaf9a273c9f4efcbcead20df26e163d
Autor:
Keita Takahashi, Hideyuki Takeuchi, Yuji Kurihara, Hiroshi Doi, Misako Kunii, Kenichi Tanaka, Haruko Nakamura, Ryoko Fukai, Atsuko Tomita-Katsumoto, Mikiko Tada, Yuichi Higashiyama, Hideto Joki, Shigeru Koyano, Kohtaro Takei, Fumiaki Tanaka
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-7 (2018)
Abstract Background Although inflammation in the central nervous system is responsible for multiple neurological diseases, the lack of appropriate biomarkers makes it difficult to evaluate inflammatory activities in these diseases. Therefore, a new b
Externí odkaz:
https://doaj.org/article/567adf62af5f46f28b68e61013f503bd
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184258 (2017)
Nogo receptor-1 (NgR1) and its ligands inhibit neuronal plasticity and limit functional recovery after brain damage such as ischemic stroke. We have previously shown that lateral olfactory tract usher substance (LOTUS) antagonizes NgR1-mediated signa
Externí odkaz:
https://doaj.org/article/52479099e2814d41a0faa826255d1049
Autor:
Tomoko Hirokawa, Kohtaro Takei
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 7, Pp 1193-1194 (2018)
Externí odkaz:
https://doaj.org/article/5ab11fa1295041c383b041a19750626a
Autor:
Yuji Kurihara, Kohtaro Takei
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 1, Pp 46-48 (2015)
Externí odkaz:
https://doaj.org/article/6dea0cb955344aa8807ed11bd770efa4
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159157 (2016)
Cartilage acidic protein 1 (CRTAC1) was recently identified as an elevated protein in the synovial fluid of patients with osteoarthritis (OA) by a proteomic analysis. This gene is also upregulated in both human and mouse OA by transcriptomic analysis
Externí odkaz:
https://doaj.org/article/08bf477862e14d25b74db6b5ca29b313
Autor:
Yasuhiro Kamata, Shuhei Ito, Hideyuki Okano, Satoshi Nori, Morio Matsumoto, Kohtaro Takei, Narihito Nagoshi, Masaya Nakamura, Kota Kojima
Publikováno v:
Stem Cell Reports
Summary Functional recovery is still limited mainly due to several mechanisms, such as the activation of Nogo receptor-1 (NgR1) signaling, when human induced pluripotent stem cell-derived neural stem/progenitor cells (hiPSC-NS/PC) are transplanted fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24a77792ac00e96f9124a85f6ea91c7
https://doi.org/10.1016/j.stemcr.2021.09.006
https://doi.org/10.1016/j.stemcr.2021.09.006