Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kohshiro Fukushima"'
Autor:
Norikazu Yabuta, Chie Ota, Towa Sasakura, Yoko Naito, Daisuke Okuzaki, Kohshiro Fukushima, Hiroshi Nojima
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract p63, a transcriptional factor that belongs to the p53 family, regulates epidermal differentiation, stemness, cell death, tumorigenesis, metastasis, and senescence. However, its molecular mechanism remains elusive. We report here that TAp63 p
Externí odkaz:
https://doaj.org/article/d823cb5749da467494f672201e541b3e
Autor:
Yukihiro Nishikawa, Daisuke Okuzaki, Kohshiro Fukushima, Satomi Mukai, Shouichi Ohno, Yuki Ozaki, Norikazu Yabuta, Hiroshi Nojima
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134137 (2015)
Withaferin A (WA), a major bioactive component of the Indian herb Withania somnifera, induces cell death (apoptosis/necrosis) in multiple types of tumor cells, but the molecular mechanism underlying this cytotoxicity remains elusive. We report here t
Externí odkaz:
https://doaj.org/article/4ea88ae708914f23bba121e259a9829a
Autor:
Yoko Naito, Norikazu Yabuta, Towa Sasakura, Kohshiro Fukushima, Moe Fukuzawa, Ayumi Okamoto, Satomi Mukai, Masami Nozaki, Gregory D. Longmore, Hiroshi Nojima
Publikováno v:
Oncotarget
Cancer stem cells (CSCs), which play important roles in tumor initiation and progression, are resistant to many types of therapies. However, the regulatory mechanisms underlying CSC-specific properties, including self-renewal, are poorly understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761bb23ddfd469fff76a6ac14af1a84c
https://doi.org/10.18632/oncotarget.26583
https://doi.org/10.18632/oncotarget.26583
Autor:
Hiroshi Nojima, Daisuke Okuzaki, Norikazu Yabuta, Yoko Naito, Chie Ota, Towa Sasakura, Kohshiro Fukushima
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
p63, a transcriptional factor that belongs to the p53 family, regulates epidermal differentiation, stemness, cell death, tumorigenesis, metastasis, and senescence. However, its molecular mechanism remains elusive. We report here that TAp63 phosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47803cad7c3a151bd77646676f41bab1
https://doaj.org/article/d823cb5749da467494f672201e541b3e
https://doaj.org/article/d823cb5749da467494f672201e541b3e
Autor:
Shouichi Ohno, Norikazu Yabuta, Kaori Ota, Yoko Naito, Kohshiro Fukushima, Toshihiro Uchihashi, Hiroshi Nojima, Yusuke Yabuno, Mikihiko Kogo
Publikováno v:
Oncotarget
// Toshihiro Uchihashi 1, * , Kaori Ota 2, * , Yusuke Yabuno 1, * , Shouichi Ohno 2 , Kohshiro Fukushima 2 , Yoko Naito 2 , Mikihiko Kogo 1 , Norikazu Yabuta 2, ** and Hiroshi Nojima 2 1 First Department of Oral and Maxillofacial Surgery, Graduate Sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab58212b7e8c48f38d675f70c8b19e21
https://doi.org/10.18632/oncotarget.20696
https://doi.org/10.18632/oncotarget.20696
Autor:
Hiroshi Nojima, Towa Sasakura, Hiroyuki Shimizu, Kohshiro Fukushima, Toshihiro Uchihashi, Yusuke Yabuno, Mikihiko Kogo, Norikazu Yabuta, Kaori Ota, Yoko Naito
Publikováno v:
Cell Cycle
Clathrin regulates mitotic progression, in addition to membrane trafficking. However, the detailed regulatory mechanisms of clathrin during mitosis remain elusive. Here, we demonstrate novel regulation of clathrin during mitotic phase of the cell cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782be7dd8f4116360599d5d60d39c4d1
https://pubmed.ncbi.nlm.nih.gov/31272276
https://pubmed.ncbi.nlm.nih.gov/31272276
Autor:
Yoko Naito, Mian Wang, Yorika Kato, Kohshiro Fukushima, Toshihiro Uchihashi, Norikazu Yabuta, Satomi Mukai, Hiroshi Nojima
Cyclin G-associated kinase (GAK) harbors a consensus phosphorylation motif (Y412) for c-Src; however, its physiological significance remains elusive. Here, we show that GAK is phosphorylated by c-Src not only at Y412 but also at Y1149. An anti-GAK-pY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce87c30c413b640e0ff4e51f838b07c
https://europepmc.org/articles/PMC5351929/
https://europepmc.org/articles/PMC5351929/
Autor:
Yoko Naito, Daisuke Okuzaki, Norikazu Yabuta, Kaori Ota, Yukihiro Nishikawa, Shouichi Ohno, Kosuke Torigata, Towa Sasakura, Kohshiro Fukushima, Eiichi Morii, Toshihiro Uchihashi, Jun-ichiro Ikeda, Daisaku Miura, Takashi Kasama, Yorika Kato, Hiroshi Nojima, Mian Wang
Publikováno v:
Scientific Reports
Cyclin G1 (CycG1) and Cyclin G2 (CycG2) play similar roles during the DNA damage response (DDR), but their detailed roles remain elusive. To investigate their distinct roles, we generated knockout mice deficient in CycG1 (G1KO) or CycG2 (G2KO), as we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0059063f8ac5250c27d5e6f11f479c57
http://europepmc.org/articles/PMC5159814
http://europepmc.org/articles/PMC5159814
Autor:
Kazuyuki Yoshizaki, Hiroshi Nojima, Daisuke Okuzaki, Toshio Tanaka, Takanori Washio, Kohshiro Fukushima, Toru Hirano
Publikováno v:
Scientific Reports
Behçet’s disease (BD), a chronic systemic inflammatory disorder, is characterized by recurrent oral and genital mucous ulcers, uveitis and skin lesions. We performed DNA microarray analysis of peripheral blood mononuclear cell (PBMC) mRNA from 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4786f20d6b865e1f94526c4a05ccd6ce
https://pubmed.ncbi.nlm.nih.gov/26785681
https://pubmed.ncbi.nlm.nih.gov/26785681
Autor:
Hiroshi Nojima, Yukihiro Nishikawa, Norikazu Yabuta, Kohshiro Fukushima, Daisuke Okuzaki, Satomi Mukai, Yuki Ozaki, Shouichi Ohno
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134137 (2015)
PLoS ONE
PLoS ONE
Withaferin A (WA), a major bioactive component of the Indian herb Withania somnifera, induces cell death (apoptosis/necrosis) in multiple types of tumor cells, but the molecular mechanism underlying this cytotoxicity remains elusive. We report here t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cef45a0be49726dab50a23c3bb8b7f2
http://europepmc.org/articles/PMC4521694?pdf=render
http://europepmc.org/articles/PMC4521694?pdf=render