Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Kohshin Washiyama"'
Autor:
Naoyuki Ukon, Songji Zhao, Kohshin Washiyama, Noboru Oriuchi, Chengbo Tan, Saki Shimoyama, Miho Aoki, Hitoshi Kubo, Kazuhiro Takahashi, Hiroshi Ito
Publikováno v:
EJNMMI Physics, Vol 7, Iss 1, Pp 1-14 (2020)
Abstract Background 211At is one of the ideal nuclides for targeted radionuclide therapies (TRTs). Meta-[211At]astatobenzylguanidine (211At-MABG) has been proposed for the treatment of pheochromocytoma. To effectively use these radiopharmaceuticals,
Externí odkaz:
https://doaj.org/article/e4687f9122f842ff8b27674aedcb0b44
Autor:
Mitsuyoshi Yoshimoto, Yukie Yoshii, Hiroki Matsumoto, Mitsuhiro Shinada, Masashi Takahashi, Chika Igarashi, Fukiko Hihara, Tomoko Tachibana, Ayano Doi, Tatsuya Higashi, Hirofumi Fujii, Kohshin Washiyama
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1706 (2021)
Actinium-225 (225Ac) is a promising radionuclide used in targeted alpha therapy (TAT). Although 225Ac labeling of bifunctional chelating ligands is effective, previous in vivo studies reported that free 225Ac can be released from the drugs and that s
Externí odkaz:
https://doaj.org/article/0469259c26574176ac2f6b94f2f08236
Autor:
Masato Kobayashi, Toshitaka Kato, Kohshin Washiyama, Masaaki Ihara, Asuka Mizutani, Kodai Nishi, Leo G Flores, Ryuichi Nishii, Keiichi Kawai
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213397 (2019)
BackgroundAlthough a 3-arm DOTA construct, which has three carboxylic acids, h has been applied for conjugation to many peptides, we investigated if a 4-arm DOTA construct conjugated to peptides improves chemical properties for melanoma imaging of th
Externí odkaz:
https://doaj.org/article/1ba7e45020364dda9d75f58540dc78cd
Autor:
Sture Lindegren, Luciana N S Andrade, Tom Bäck, Camila Maria L Machado, Bruno Brasil Horta, Carlos Buchpiguel, Ana Maria Moro, Oswaldo Keith Okamoto, Lars Jacobsson, Elin Cederkrantz, Kohshin Washiyama, Emma Aneheim, Stig Palm, Holger Jensen, Maria Carolina B Tuma, Roger Chammas, Ragnar Hultborn, Per Albertsson
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126298 (2015)
The aim of this preclinical study was to evaluate the characteristics of the monoclonal antibody Rebmab200, which is a humanized version of the ovarian-specific murine antibody MX35. This investigation contributes to the foundation for future clinica
Externí odkaz:
https://doaj.org/article/170e44cfa9b843fbbf83f01fd750231f
Autor:
Hideaki Shiga, Junichi Taki, Kohshin Washiyama, Junpei Yamamoto, Sakae Kinase, Koichi Okuda, Seigo Kinuya, Naoto Watanabe, Hisao Tonami, Kichiro Koshida, Ryohei Amano, Mitsuru Furukawa, Takaki Miwa
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57671 (2013)
PURPOSE: The aim of this study was to assess whether migration of thallium-201 ((201)Tl) to the olfactory bulb were reduced in patients with olfactory impairments in comparison to healthy volunteers after nasal administration of (201)Tl. PROCEDURES:
Externí odkaz:
https://doaj.org/article/9e09f30cebec4a9cac5b099889e8485e
Autor:
Saki Hirata, Seigo Kinuya, Kazuma Ogawa, Kenji Mishiro, Kohshin Washiyama, Hiroaki Echigo, Yoji Kitamura, Kazuhiro Shiba, Kazuhiro Takahashi
Publikováno v:
Molecular Pharmaceutics. 18:3553-3562
Probes for radiotheranostics could be produced by introducing radionuclides with similar chemical characteristics into the same precursors. We recently developed an 211At-labeled RGD peptide and a corresponding radioiodine-labeled RGD peptide. Both l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00b7bce06dcc6f8f4ca594c54b930db7
https://doi.org/10.1021/acs.molpharmaceut.1c00460
https://doi.org/10.1021/acs.molpharmaceut.1c00460
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 329:1459-1465
In this study, the volatile adsorption temperature of volatile astatine species was studied using the 211At radionuclide produced via the 209Bi(4He,2n)211At nuclear reaction. Volatile astatine was separated from irradiated bismuth via dry distillatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5c84c93c7632915c504d71d054008d5
https://doi.org/10.1007/s10967-021-07879-6
https://doi.org/10.1007/s10967-021-07879-6
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 329(3):1459-1465
In this study, the volatile adsorption temperature of volatile astatine species was studied using the 211At radionuclide produced via the 209Bi(4He,2n)211At nuclear reaction. Volatile astatine was separated from irradiated bismuth via dry distillatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::2a43ae9ab827b0c4e3f8bcc6e2110483
https://repo.qst.go.jp/records/83518
https://repo.qst.go.jp/records/83518
Autor:
Sadaharu Miyazono, Kazuma Ogawa, Junichi Taki, Hideaki Shiga, Hiroshi Wakabayashi, Masami Kumai, Tomo Hiromasa, Kohshin Washiyama, Tomohiro Noguchi, Takaki Miwa, Seigo Kinuya
Publikováno v:
Molecular Neurobiology
In this study, we determined whether the 201Tl (thallium-201)-based olfactory imaging is affected if olfactory sensory neurons received reduced pre-synaptic inhibition signals from dopaminergic interneurons in the olfactory bulb in vivo. The thallium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2973d704a3759e4c94dc2c3009fa49
https://doi.org/10.1007/s12035-020-02078-y
https://doi.org/10.1007/s12035-020-02078-y
Autor:
Miho Aoki, Kazuma Ogawa, Songji Zhao, Kazuhiro Takahashi, Ken-ichi Nishijima, Kohshin Washiyama, Saki Shimoyama, Chengbo Tan, Naoyuki Ukon
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:538-545
There are various diagnostic and therapeutic agents for prostate cancer using bombesin (BBN) derivatives, but astatine-211 (211At)-labeled BBN derivatives have yet to be studied. This study presented a preliminary evaluation of 211At-labeled BBN deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066086de2000b6cf06cc555b6a19e139
https://doi.org/10.1248/cpb.c20-00077
https://doi.org/10.1248/cpb.c20-00077