Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Koho Miyoshi"'
Autor:
Koho Miyoshi
Publikováno v:
Psychogeriatrics. 9:67-72
There are two types of dementia with early onset: (i) presenile dementias; and (ii) senile dementias with early onset. Most patients who develop dementia before 65 years of age have Alzheimer's disease (AD). The remainder are likely to have vascular
Autor:
Keiko Taguchi, Tetsuro Miki, Minoru Yasuda, Hidehisa Yamagata, Takuo Nomura, Katsuhiko Kohara, Koho Miyoshi, Miho Matsubara-Tsutsui
Publikováno v:
American Journal of Medical Genetics. 114:292-298
Early onset familial Alzheimer disease (FAD) has been associated with mutations in three genes, of which presenilin 1 (PSEN1) mutations are the most frequent. We reported previously a variant form of FAD, due to deletion of exon 9 of PSEN1, with spas
Autor:
Koho Miyoshi
Publikováno v:
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 37:188-191
Autor:
Yoshio Morita, Masahiro Kokai, Koho Miyoshi, Kazuyuki Ohara, Takaya Nakajima, Shigeru Takauchi
Publikováno v:
Neuropathology. 19:161-171
The populations and loss of neurons, the density of neurofibrillary tangles (NFT) and senile plaque (SP), and the macroscopic shrinkage of the subcortical areas in patients with Alzheimer's disease (AD) were quantitatively evaluated using computer-ba
Autor:
Koho Miyoshi
Publikováno v:
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 36:1-7
Publikováno v:
Psychiatry and Clinical Neurosciences. 52:499-505
The purpose of the present study was to investigate the ictal and interictal changes in cardiac autonomic function (CAF), and the relationship between the interictal change in CAF to the electroencephalogram (EEG) and clinical findings. In two patien
Publikováno v:
Neuropathology. 16:231-238
The numbers of neurofibrillary tangles(NFT) in the subcortical nuclei detected in Gallyas-Nissl double stained sections was evaluated with computer-based image analysis techniques. This was undertaken to examine the susceptibility to NFT formation an
Publikováno v:
Journal of the Neurological Sciences. 142:7-11
The initial stage of Alzheimer's disease is characterized by neuropathological alteration in the entorhinal cortex. To model one aspect of the neurodegeneration observed and to investigate anatomical changes of the hippocampus associated with unilate
Publikováno v:
European Neurology. 36:49-54
Depression and hallucination are the two main psychiatric symptoms in parkinsonian patients. Depressive features in Parkinson patients are very close to those of endogenous depression, except for a relative lack of anxiety, irritability, suicidal ide
Autor:
S Takauchi, Koho Miyoshi
Publikováno v:
Acta Neuropathologica. 89:8-16
Neurofibrillary tangles (NFTs), which are composed of paired helical filament (PHF)-like filaments, were induced by the long-term intraventricular infusion of leupeptin, a potent protease inhibitor. The fibrils composing the NFTs were 20 nm in maxima