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Autor:
Yoshinori Koga, Akinori Kimura, Hirofumi Nishi, Hironori Toshima, Takehiko Sasazuki, Takeshi Koyanagi, Haruhito Harada, Kyo Adachi, Kohmei Matsuyama, Tsutomu Imaizumi, Seikoh Yasunaga
Publikováno v:
Circulation. 91:2911-2915
Background Hypertrophic cardiomyopathy (HCM) is characterized by myocardial hypertrophy of unknown etiology. Missense mutations of the cardiac β–myosin-heavy-chain (β-MHC) gene that may be responsible for cardiac hypertrophy have been detected in