Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kohlsdorfer Christian"'
Autor:
Straub, Alexander, Benet-Buckholz, Jordi, Fröde, Rita, Kern, Armin, Kohlsdorfer, Christian, Schmitt, Peter, Schwarz, Thomas, Siefert, Hans-Martin, Stasch, Johannes-Peter
Publikováno v:
In Bioorganic & Medicinal Chemistry 2002 10(6):1711-1717
Publikováno v:
Journal of Pharmaceutical Sciences. 93:816-830
Quantification of protein binding of new chemical entities is an important early screening step during drug discovery and is of fundamental interest for the estimation of safety margins during drug development. In this publication, we describe the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb65725d8f17efb4d5751208607b01c8
https://doi.org/10.1002/jps.10588
https://doi.org/10.1002/jps.10588
Autor:
Alexander Straub, Thomas Schwarz, Armin Kern, Jordi Benet-Buckholz, Peter D. Schmitt, Hans Martin Siefert, Johannes-Peter Stasch, Rita Fröde, Kohlsdorfer Christian
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:1711-1717
The pyrazolopyridine stimulators of soluble guanylate cyclase BAY 41-2272 and 41-8543 were oxidised in rats and dogs at their 5-pyrimidinyl-cyclopropyl and -morpholino residue. These metabolites activate the soluble guanylate cyclase, induce vasoelax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08162df13d86c87750fda7d5e8d35dee
https://doi.org/10.1016/s0968-0896(02)00034-2
https://doi.org/10.1016/s0968-0896(02)00034-2
Autor:
Boettcher, Michael-Friedrich, Heinig, Roland, Schmeck, Carsten, Kohlsdorfer, Christian, Ludwig, Matthias, Schaefer, Anja, Gelfert-Peukert, Sabine, Wensing, Georg, Weber, Olaf
To determine pharmacokinetics (PK), pharmacodynamics (PD), tolerability and safety of BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein (CETP).The first in man (FIM) study investigated the safety, tolerability, pharmacodynamics an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06641daeaebb6d6788bb46166dd84cd3
https://europepmc.org/articles/PMC3269580/
https://europepmc.org/articles/PMC3269580/
Autor:
Rita Fröde, Johannes-Peter Stasch, Hans-Martin Siefert, Jordi Benet-Buchholz, Armin Kern, Alexander Straub, Thomas Schwarz, Kohlsdorfer Christian, Peter D. Schmitt
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:3075
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483ab3cb427d38f8c1a1fed57d9036b4
https://doi.org/10.1016/s0968-0896(02)00134-7
https://doi.org/10.1016/s0968-0896(02)00134-7
Autor:
Schuhmacher, Joachim, Kohlsdorfer, Christian, Bühner, Klaus, Brandenburger, Tim, Kruk, Renate
Publikováno v:
Journal of Pharmaceutical Sciences; April 2004, Vol. 93 Issue: 4 p816-830, 15p
Autor:
Matzke, Michael, Beckermann, Bernd, Fruchtmann, Romanis, Fugmann, Burkhard, Gardiner, Phillip J., Goossens, John, Flatzelmann, Armin, Junge, Bodo, Keldenich, Jörg, Kohlsdorfer, Christian, Mohrs, Klaus-Helmut, Müller-Peddinghaus, Reiner, Raddatz, Siegfried
Publikováno v:
European Journal of Medicinal Chemistry; January 1995, Vol. 30 Issue: 1, Number 1 Supplement 1 p441s-451s, 11p
Autor:
Kohlsdorfer, Christian
Thesis--Cologne.
In Periodical Room.
In Periodical Room.
Externí odkaz:
http://catalog.hathitrust.org/api/volumes/oclc/21646563.html
Autor:
Straub, Alexander, Benet-Buchholz, Jordi, Fröde, Rita, Kern, Armin, Kohlsdorfer, Christian, Schmitt, Peter, Schwarz, Thomas, Siefert, Hans-Martin, Stasch, Johannes-Peter
Publikováno v:
In Bioorganic & Medicinal Chemistry 2002 10(9):3075-3075
Autor:
Boettcher MF; Bayer Pharma AG, 42096 Wuppertal, Germany. michael-friedrich.boettcher@bayer.com, Heinig R, Schmeck C, Kohlsdorfer C, Ludwig M, Schaefer A, Gelfert-Peukert S, Wensing G, Weber O
Publikováno v:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2012 Feb; Vol. 73 (2), pp. 210-8.