A novel pretherapeutic gene expression-based risk score for treatment guidance in gastric cancer

Autor: Bauer, L., Hapfelmeier, A., Blank, S., Reiche, M., Slotta-Huspenina, J., Jesinghaus, M., Novotny, A., Schmidt, T., Grosser, B., Kohlruss, M., Weichert, W., Ott, K., Keller, G. ^*

Publikováno v: In Annals of Oncology January 2018 29(1):127-132

Diverse 'just-right' levels of chromosomal instability and their clinical implications in neoadjuvant treated gastric cancer.

Autor: Kohlruss M; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Krenauer M; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Grosser B; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany.; Institute of Pathology and Molecular Diagnostics, University Hospital Augsburg, Augsburg, Germany., Pfarr N; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Jesinghaus M; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany.; Institute of Pathology, University Hospital Marburg, Marburg, Germany., Slotta-Huspenina J; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Novotny A; Department of Surgery, TUM School of Medicine, Technical University of Munich, Munich, Germany., Hapfelmeier A; Institute of Medical Informatics, Statistics and Epidemiology, Technical University of Munich, Munich, Germany.; Institute of General Practice and Health Services Research, TUM School of Medicine, Technical University of Munich, Munich, Germany., Schmidt T; Department of Surgery, University of Heidelberg, Heidelberg, Germany.; Department of Surgery, Universitätsklinikum Köln, Köln, Germany., Steiger K; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Institute of Pathology, Munich, Germany., Gaida MM; Institute of Pathology, University of Heidelberg, Heidelberg, Germany.; Institute of Pathology, University Medical Center Mainz, JGU-Mainz, Mainz, Germany., Reiche M; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Bauer L; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Ott K; Department of Surgery, RoMed Klinikum Rosenheim, Rosenheim, Germany., Weichert W; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Institute of Pathology, Munich, Germany., Keller G; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany. gisela.keller@tum.de.

Publikováno v: British journal of cancer [Br J Cancer] 2021 Dec; Vol. 125 (12), pp. 1621-1631. Date of Electronic Publication: 2021 Oct 20.

Significant Tumor Regression after Neoadjuvant Chemotherapy in Gastric Cancer, but Poor Survival of the Patient? Role of MHC Class I Alterations.

Autor: Hiltner T; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany., Szörenyi N; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany., Kohlruss M; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany., Hapfelmeier A; Institute of Medical Informatics, Statistics and Epidemiology, Technical University of Munich, 81675 Munich, Germany.; Institute of General Practice and Health Services Research, School of Medicine, Technical University of Munich, 81675 Munich, Germany., Herz AL; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany., Slotta-Huspenina J; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany., Jesinghaus M; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany.; Institute of Pathology, University Hospital Marburg, 35043 Marburg, Germany., Novotny A; Department of Surgery, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany., Lange S; II. Medizinische Klinik, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany., Ott K; Department of Surgery, Klinikum Rosenheim, 83022 Rosenheim, Germany., Weichert W; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Institute of Pathology, 81675 Munich, Germany., Keller G; Institute of Pathology, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2023 Jan 26; Vol. 15 (3). Date of Electronic Publication: 2023 Jan 26.

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Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study.

Autor: Muti HS; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Heij LR; Department of Surgery and Transplantation, University Hospital RWTH Aachen, Aachen, Germany; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Keller G; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Kohlruss M; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany., Langer R; Institute of Pathology, Inselspital, University of Bern, Switzerland; Institute of Pathology and Molecular Pathology, Kepler University Hospital, Johannes Kepler University Linz, Linz, Austria., Dislich B; Institute of Pathology, Inselspital, University of Bern, Switzerland., Cheong JH; Department of Surgery, Yonsei University Health System, Yonsei University College of Medicine, Seoul, South Korea., Kim YW; Center for Gastric Cancer, National Cancer Center, Goyang, South Korea., Kim H; Department of Pathology, Yonsei University College of Medicine, Seoul, South Korea., Kook MC; Department of Pathology, National Cancer Center, Goyang, South Korea., Cunningham D; Department of Medicine, Gastrointestinal and Lymphoma Units, The Royal Marsden NHS Foundation Trust, London, UK., Allum WH; Department of Surgery, Royal Marsden Hospital, London, UK., Langley RE; Medical Research Council Clinical Trials Unit, University College London, London, UK., Nankivell MG; Medical Research Council Clinical Trials Unit, University College London, London, UK., Quirke P; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Hayden JD; Department of Oesophago-Gastric Surgery, St James's University Hospital, Leeds, UK., West NP; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Irvine AJ; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Yoshikawa T; Department of Gastric Surgery, National Cancer Center Hospital, Tokyo, Japan., Oshima T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan., Huss R; Institute of Pathology and Molecular Diagnostics, University Hospital Augsburg, Augsburg, Germany., Grosser B; Institute of Pathology and Molecular Diagnostics, University Hospital Augsburg, Augsburg, Germany., Roviello F; Department of Medicine, Surgery and Neuroscience, Unit of General Surgery and Surgical Oncology, University of Siena, Italy., d'Ignazio A; Department of Medicine, Surgery and Neuroscience, Unit of General Surgery and Surgical Oncology, University of Siena, Italy., Quaas A; Institute of Pathology, University Hospital Cologne, Cologne, Germany., Alakus H; Department of General, Visceral, Cancer and Transplantation Surgery, University Hospital Cologne, Cologne, Germany., Tan X; Department of Surgery and Transplantation, University Hospital RWTH Aachen, Aachen, Germany., Pearson AT; Department of Medicine, University of Chicago Medicine, Chicago, IL, USA., Luedde T; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Düsseldorf, Germany., Ebert MP; Department of Medicine II, Mannheim Institute for Innate Immunoscience and Clinical Cooperation Unit Healthy Metabolism, Center of Preventive Medicine and Digital Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Jäger D; Department of Medical Oncology, National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Trautwein C; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Gaisa NT; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Grabsch HI; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK; Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, Netherlands., Kather JN; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK; Department of Medical Oncology, National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany. Electronic address: jkather@ukaachen.de.

Publikováno v: The Lancet. Digital health [Lancet Digit Health] 2021 Oct; Vol. 3 (10), pp. e654-e664. Date of Electronic Publication: 2021 Aug 17.