Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kohki Okada"'
Publikováno v:
Biology, Vol 13, Iss 11, p 916 (2024)
S100A8 is a protein that is abundant in neutrophils and macrophages (MΦ), but its role in inflammation remains unclear. This study aimed to assess the immunological role(s) of S100A8 in acute intestinal inflammation in rats and its role in MΦ. Rat
Externí odkaz:
https://doaj.org/article/236341c43ce3499dad7c74f31b9eabdb
Autor:
Kohki Okada, Kano Matsuo, Miku Amada, Saki Kashihara, Koto Katsuragi, Miharu Doumae, Masaki Moriwaki, Ryouhei Yamauchi, Jun Yoshida
Publikováno v:
Gastrointestinal Disorders, Vol 5, Iss 4, Pp 474-486 (2023)
Ulcerative colitis (UC) is a relapsing and remitting disease that causes chronic inflammation and ulceration of colonic tissue, especially in the rectum region. Although sugars are rapidly digested and absorbed and can be efficiently utilized as ener
Externí odkaz:
https://doaj.org/article/f03b54d8e0484fdbbfabcac0233f3ccf
Autor:
Kohki Okada, Kano Matsuo
Publikováno v:
Foods, Vol 12, Iss 8, p 1621 (2023)
Food poisoning can be caused by the potato alkaloids α-solanine (SO) and α-chaconine (CHA). Therefore, this study aimed to establish new enzyme-linked immunosorbent assays (ELISAs) for detecting these two toxins in biological samples and potato ext
Externí odkaz:
https://doaj.org/article/a7372fbccbd24724b1857ed43d12b8a3
Autor:
Kohki Okada, Kano Matsuo
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 922 (2023)
Ulcerative colitis (UC) is an intractable disease that causes persistent colonic inflammation. Numerous studies have reported that smoking can afford clinical benefits in UC. This study aimed to elucidate whether nicotine, the main component in cigar
Externí odkaz:
https://doaj.org/article/434f0c3f125741f1986d9c651acb6829
Publikováno v:
Heliyon, Vol 7, Iss 3, Pp e06554- (2021)
Aims: Ulcerative colitis (UC), characterized by chronic inflammation and its recurrence in the large intestine, is well known as inflammatory bowel disease (IBD). Suitable biomarkers specific for UC are poorly understood till date. We aimed to discov
Externí odkaz:
https://doaj.org/article/86cdb5d74cf7494aa1c6a7936d7d0114
Publikováno v:
Heliyon, Vol 6, Iss 2, Pp e03470- (2020)
Aims: The clinical significance of circulating S100A8/A9 (calprotectin) in patients with ulcerative colitis (UC) is poorly understood. We examined whether serum S100A8/A9 is a good biomarker for UC, and whether the serum level is a useful index for t
Externí odkaz:
https://doaj.org/article/a0c942e9a94d4f6ca0de415f5e6ee5de
Autor:
Kohki Okada, Masaki Ikemoto
Publikováno v:
Biology, Vol 11, Iss 4, p 494 (2022)
Ulcerative colitis (UC) is characterized by chronic inflammation of the large intestine, repeated remissions, and symptom relapses. Although unknown components in colonic regions are deeply involved in the pathogenesis of UC, the causes of UC develop
Externí odkaz:
https://doaj.org/article/fa45af6c7d8e483484f13706c9e96568
Autor:
Masaki Ikemoto, Kohki Okada
Publikováno v:
Inflammation
We newly developed a hybrid protein, tentatively named rMIKO-1, using gene technology. We herein investigated the effects of rMIKO-1 on activated macrophages and discussed its potential as a suppressor of experimental colitis. Fluorescent microscopy
Publikováno v:
Laboratory Medicine. 50:370-380
Background The clinical significance of human S100A8/A9 (h-S100A8/A9) in patients with inflammatory bowel disease (IBD) is poorly understood. Objective To clarify whether serum S100A8/A9 is a sensitive biomarker for IBD. Methods Serum specimens from
Publikováno v:
Heliyon
Aims Ulcerative colitis (UC), characterized by chronic inflammation and its recurrence in the large intestine, is well known as inflammatory bowel disease (IBD). Suitable biomarkers specific for UC are poorly understood till date. We aimed to discove