Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kohki Matsubara"'
Autor:
Shinnosuke Koketsu, Kohki Matsubara, Yoshino Ueki, Yoshiaki Shinohara, Koichi Inoue, Satona Murakami, Takatoshi Ueki
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23738- (2024)
Adverse environmental stress causes depressive symptoms with the impairments of memory formation, cognition, and motivation, however, their underlying neural bases have not been well understood, especially based on the observation of living animals.
Externí odkaz:
https://doaj.org/article/d2a68db596bd4b58a01d273aecb0a780
Autor:
Shinnosuke Koketsu, Kohki Matsubara, Yoshino Ueki, Yoshiaki Shinohara, Koichi Inoue, Satona Murakami, Takatoshi Ueki
Accumulated evidence demonstrate that environmental stress affects the hippocampus, functioning in cognition and sociality, and causes various depressive symptoms. In addition, recent findings showed that environmental stress influenced the hippocamp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f52eda6c92e159a5841f797930b0f20
https://doi.org/10.1101/2023.01.30.526359
https://doi.org/10.1101/2023.01.30.526359
Autor:
Yuichiro Sugiyama, Toshihiko Suzuki, Alkisti Mikrogeorgiou, Akihito Yamamoto, Hiroshi Yukawa, Masahiro Tsuji, Kohki Matsubara, Hitoshi Hirata, Shinobu Shimizu, Kazuto Ueda, Yoshinobu Baba, Masahiro Hayakawa, Yuka Tsukagoshi Okabe, Yuma Kitase, Yoshiyuki Takahashi, Yoshiaki Sato
Publikováno v:
Stem Cells and Development. 29:63-74
Recently, cell therapy has been developed as a novel treatment for perinatal hypoxic-ischemic encephalopathy (HIE), which is an important cause of neurological disorder and death, and stem cells from human exfoliated deciduous teeth (SHED) express ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9f69a0955a220141025f9a3eee91ec
https://doi.org/10.1089/scd.2019.0221
https://doi.org/10.1089/scd.2019.0221
Publikováno v:
Stem Cells. 35:641-653
Peripheral nerves (PNs) exhibit remarkable self-repairing reparative activity after a simple crush or cut injury. However, the neuronal transection involving a nerve gap overwhelms their repairing activity and causes persistent paralysis. Here, we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819f4b606cec50f006fb609017861931
https://doi.org/10.1002/stem.2534
https://doi.org/10.1002/stem.2534
Autor:
Minoru Ueda, Hidemi Goto, Yoshihiro Matsushita, Hirotaka Wakayama, Masatoshi Ishigami, Kohki Matsubara, Megumi Kondo, Akihito Yamamoto
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:1888-1896
In acute liver failure (ALF), a poorly controlled innate immune response causes massive hepatic destruction, which elicits a systemic inflammatory response, progressive multiple organ failure and ultimate sudden death. Although the liver has inherent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b36a9c1afb32f8bf967ccbd3c051d20e
https://doi.org/10.1002/term.2086
https://doi.org/10.1002/term.2086
Autor:
Kinji Ohno, Kiyoshi Sakai, Hiromi Fujii, Akihito Yamamoto, Minoru Ueda, Kohki Matsubara, Mikako Ito
Publikováno v:
Brain Research. 1613:59-72
Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by the loss of nigrostriatal dopaminergic (DAergic) neurons and the depletion of striatal dopamine. Here we show that DAergic-neuron-like cells could be efficiently induced f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf7cbd279a276508938c4253eb8d524
https://doi.org/10.1016/j.brainres.2015.04.001
https://doi.org/10.1016/j.brainres.2015.04.001
Autor:
Akihito Yamamoto, Kohki Matsubara, Tetsuya Ishikawa, Hidemi Goto, Hideharu Hibi, Masatoshi Ishigami, Minoru Ueda, Yoshihiro Matsushita, Marina Hirata, Yoshiki Hirooka, Takanori Ito
Publikováno v:
Scientific Reports
Effective treatments for acute liver failure (ALF) are still lacking. We recently reported that a single intravenous administration of serum-free conditioned medium from stem cells derived from human exfoliated deciduous teeth (SHED-CM) into the D-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f4c3e817cb29f975067056be50977
https://doi.org/10.1038/srep44043
https://doi.org/10.1038/srep44043
Autor:
Kiyoshi Sakai, Mari Yamagata, Kohki Matsubara, Kazunobu Sawamoto, Eisuke Kako, Akihito Yamamoto, Minoru Ueda, Naoko Kaneko
Publikováno v:
Stroke. 44:551-554
Background and Purpose— Perinatal hypoxia-ischemia (HI) has high rates of neurological deficits and mortality. So far, no effective treatment for HI brain injury has been developed. In this study, we investigated the therapeutic effects of stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dcb09b298bd8479aae91c3d1d3d3568
https://doi.org/10.1161/strokeaha.112.676759
https://doi.org/10.1161/strokeaha.112.676759
Autor:
Fumiya Kano, Noboru Hashimoto, Megumi Kondo, Yoshihiro Matsushita, Kohki Matsubara, Naoki Ishiguro, Akihito Yamamoto, Mariko Noda, Koichi Furukawa, Minoru Ueda, Shiro Imagama, Akio Suzumura, Kiyoshi Sakai
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(6)
Engrafted mesenchymal stem cells from human deciduous dental pulp (SHEDs) support recovery from neural insults via paracrine mechanisms that are poorly understood. Here we show that the conditioned serum-free medium (CM) from SHEDs, administered intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987a37a52a8e307aaff41abd21a901f2
https://pubmed.ncbi.nlm.nih.gov/25673840
https://pubmed.ncbi.nlm.nih.gov/25673840
Autor:
Akihito Yamamoto, Yoshinori Hasegawa, Naozumi Hashimoto, Kohki Matsubara, Noriyuki Yamamoto, Minoru Ueda, Yoshihiro Matsushita, Hirotaka Wakayama
Publikováno v:
Cytotherapy. 17(8)
Background aims Acute respiratory distress syndrome (ARDS) is a severe inflammatory disorder characterized by acute respiratory failure, resulting from severe, destructive lung inflammation and irreversible lung fibrosis. We evaluated the use of stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc1217eeac34eab54762914c3933892
https://pubmed.ncbi.nlm.nih.gov/26031744
https://pubmed.ncbi.nlm.nih.gov/26031744