Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Kohji Maruo"'
Autor:
Cathy Su, Jeffrey P. Gius, Julia Van Steenberg, Alexis H. Haskins, Kazuki Heishima, Chisato Omata, Masahiro Iwayama, Mami Murakami, Takashi Mori, Kohji Maruo, Takamitsu A. Kato
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Rosemary extract is used in food additives and traditional medicine and has been observed to contain anti-tumor activity. In this study, rosemary extract is hypothesized to induce synthetic lethality in BRCA2 deficient cells by PARP inhibiti
Externí odkaz:
https://doaj.org/article/7565a82dd66f49b1a36dd312937e9dcc
Autor:
Kazuki Heishima, Yukie Ichikawa, Kyoko Yoshida, Ryota Iwasaki, Hiroki Sakai, Takayuki Nakagawa, Yuiko Tanaka, Yuki Hoshino, Yasuhiko Okamura, Mami Murakami, Kohji Maruo, Yukihiro Akao, Takashi Mori
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Circulating microRNAs in the blood may provide diagnostic and prognostic information about canine neoplastic diseases, and their profiles may be conserved between human and canine species. We performed RT-qPCR to obtain the profiles of circu
Externí odkaz:
https://doaj.org/article/6ddeb2ca6aaf435bb2f9d64d897c1666
Autor:
Kazuki Heishima, Takashi Mori, Yukie Ichikawa, Hiroki Sakai, Yuki Kuranaga, Takayuki Nakagawa, Yuiko Tanaka, Yasuhiko Okamura, Mikio Masuzawa, Nobuhiko Sugito, Mami Murakami, Nami Yamada, Yukihiro Akao, Kohji Maruo
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 25377-25391 (2015)
Malignant endothelial proliferative diseases including human angiosarcoma (AS) and canine hemangiosarcoma (HSA) are serious diseases with a grave prognosis. Establishing liquid biopsy-based biomarkers for screening has definite clinical utility; howe
Externí odkaz:
https://doaj.org/article/785cc88ddb834b65952be7c8683db520
Autor:
Kazuki Heishima, Takashi Mori, Hiroki Sakai, Nobuhiko Sugito, Mami Murakami, Nami Yamada, Yukihiro Akao, Kohji Maruo
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137361 (2015)
MicroRNA-214 regulates both angiogenic function in endothelial cells and apoptosis in various cancers. However, the regulation and function of miR-214 is unclear in canine hemangiosarcoma, which is a spontaneous model of human angiosarcoma. The expre
Externí odkaz:
https://doaj.org/article/3c8cc545e56740a2bca82966ebd07e87
Autor:
Kazuki Heishima, Kohji Maruo, Hiroki Sakai, Mifumi Kawabe, Takashi Mori, Mami Murakami, Ryota Iwasaki
Publikováno v:
Journal of the American Animal Hospital Association. 55:35-41
Six dogs with massive hepatocellular carcinoma that was not amenable to surgery were treated by oral administration of single-agent toceranib at a dose of 2.0–3.0 mg/kg every other day for a minimum of 60 days. Partial response was achieved in thre
Publikováno v:
Journal of the American Animal Hospital Association. 52:371-377
The sternal lymph nodes receive drainage from a wide variety of structures in the thoraco-abdominal region. Evaluation of these lymph nodes is essential, especially in cancer patients. Computed tomography (CT) can detect sternal lymph nodes more accu
Autor:
Takashi Mori, Hiroki Sakai, Junpei Fukumoto, Mami Murakami, Kohji Maruo, Kisaburo Nagamune, Yasuhiro Takashima, Katsuya Kitoh
Publikováno v:
The Journal of Veterinary Medical Science
An 11-year-old cat presented with nasal discharge and lacrimation and was diagnosed with nasal lymphoma. Although the cat showed favorable progression after undergoing chemotherapy, CT imaging demonstrated enlarged pulmonary nodules caused by Toxopla
Publikováno v:
Veterinary and comparative oncology. 17(3)
MicroRNAs (miRNA) are small, noncoding RNA molecules consisting of 18 to 25 nucleotides. Malignant melanomas (MMs) are one of the most common malignancies in both dogs and humans. We previously reported that chemically modified synthetic miRNA-205 (m
Autor:
Yusuke Itoh, Satoshi Komazawa, Mifumi Kawabe, Mami Murakami, Hiroki Sakai, Takashi Mori, Kohji Maruo
Publikováno v:
The Journal of Veterinary Medical Science
We analyzed the status of tumor development in dogs by breed based on tumor cases that presented to the Department of Veterinary Pathology of the Gifu University for diagnostic examinations over eight years (2005-2012). We also calculated the crude i
Autor:
Hiroki Sakai, Takashi Mori, Naoko Matsui, Akihiro Hirata, Tomomi Kanehara, Mami Murakami, Tokuma Yanai, Kohji Maruo
Publikováno v:
Veterinary Clinical Pathology. 45:356-360
A 12-year-old, male castrated Domestic Shorthair cat was presented to Animal Medical Center of Gifu Univeristy with anorexia and vomiting. Physical examination revealed an enlarged left tonsil and right mandibular lymph node (approximately 2–3× th