Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kohji Kusano"'
Autor:
Akira Kunitomi, Ryoko Hirohata, Vanessa Arreola, Mitsujiro Osawa, Tomoaki M. Kato, Masaki Nomura, Jitsutaro Kawaguchi, Hiroto Hara, Kohji Kusano, Yasuhiro Takashima, Kazutoshi Takahashi, Keiichi Fukuda, Naoko Takasu, Shinya Yamanaka
Publikováno v:
Cell reports methods. 2(11)
Naive human induced pluripotent stem cells (iPSCs) can be generated by reprogramming somatic cells with Sendai virus (SeV) vectors. However, only dermal fibroblasts have been successfully reprogrammed this way, and the process requires culture on fee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c650225c78739591f1c366872e05e08
https://pubmed.ncbi.nlm.nih.gov/36447645
https://pubmed.ncbi.nlm.nih.gov/36447645
Autor:
Hiroshi Ishii, Takushi Nomura, Hiroyuki Yamamoto, Masako Nishizawa, Trang Thi Thu Hau, Shigeyoshi Harada, Sayuri Seki, Midori Nakamura-Hoshi, Midori Okazaki, Sachie Daigen, Ai Kawana-Tachikawa, Noriyo Nagata, Naoko Iwata-Yoshikawa, Nozomi Shiwa, Tadaki Suzuki, Eun-Sil Park, Maeda Ken, Taishi Onodera, Yoshimasa Takahashi, Kohji Kusano, Ryutaro Shimazaki, Yuriko Suzaki, Yasushi Ami, Tetsuro Matano
Publikováno v:
Cell Reports Medicine
Effective vaccines are essential for the control of the COVID-19 pandemic. Currently-developed vaccines inducing SARS-CoV-2 spike (S) antigen-specific neutralizing antibodies (NAbs) are effective, but the appearance of NAb-resistant S variant viruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956377056f5082668b87d46e036cb0f6
https://pubmed.ncbi.nlm.nih.gov/35233545
https://pubmed.ncbi.nlm.nih.gov/35233545
Autor:
Ryutaro SHIMAZAKI, Kohji KUSANO
Publikováno v:
Translational and Regulatory Sciences. 3:122-124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f672f66511881d27bff399f1c7eebbb
https://doi.org/10.33611/trs.2021-024
https://doi.org/10.33611/trs.2021-024
Autor:
Kohji Kusano, Noriyo Nagata, Naoko Iwata-Yoshikawa, Ken Maeda, Midori Nakamura-Hoshi, Tetsuro Matano, Trang Thi Thu Hau, Ryutaro Shimazaki, Midori Okazaki, Hiroyuki Yamamoto, Hiroshi Ishii, Ai Kawana-Tachikawa, Takushi Nomura, Nozomi Shiwa, Yuriko Suzaki, Sachie Daigen, Shigeyoshi Harada, Tadaki Suzuki, Taishi Onodera, Sayuri Seki, Yoshimasa Takahashi, Yasushi Ami, Masako Nishizawa, Park Eunsil
Publikováno v:
SSRN Electronic Journal.
Effective vaccines are essential for the control of the COVID-19 pandemic. Currently-developed vaccines inducing SARS-CoV-2 spike (S) antigen-specific neutralizing antibodies (NAbs) are effective, but the appearance of NAb-resistant S variant viruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78444841f6264fd8433195d110f15862
https://doi.org/10.2139/ssrn.3924605
https://doi.org/10.2139/ssrn.3924605
Autor:
Naoto Konomura, Jun Kobayashi, Kohji Kusano, Naoto Arai, Wakana Iwasaki, Shukuko Ikawa, Takehiko Shibata, Takeshi Shinohara
Publikováno v:
Nucleic Acids Research
RecA-family recombinase-catalyzed ATP-dependent homologous joint formation is critical for homologous recombination, in which RecA or Rad51 binds first to single-stranded (ss)DNA and then interacts with double-stranded (ds)DNA. However, when RecA or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cde7542b6c7826c700483a1be9b6d3
https://doi.org/10.1093/nar/gkw998
https://doi.org/10.1093/nar/gkw998
Autor:
Kohji Kusano, Junji Takeda, Kyoji Horie, Kosuke Yusa, Ayako Yamanishi, Masahiro Tokunaga, Chikara Kokubu
Publikováno v:
Genome Research. 23:1462-1473
Bloom syndrome, an autosomal recessive disorder of the BLM gene, confers predisposition to a broad spectrum of early-onset cancers in multiple tissue types. Loss of genomic integrity is a primary hallmark of such human malignancies, but many studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c122548de60bb554df9fcdfce973d1bd
https://doi.org/10.1101/gr.152744.112
https://doi.org/10.1101/gr.152744.112
Autor:
Kohji Kusano, Takehiko Usui, Masa-Toshi Yamamoto, Hiroaki I. Ogawa, Tohru Miura, Yoshimasa Yamana
Publikováno v:
Genetics. 191:65-78
Synthesis-dependent strand-annealing (SDSA)-mediated homologous recombination replaces the sequence around a DNA double-strand break (DSB) with a copy of a homologous DNA template, while maintaining the original configuration of the flanking regions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78314e5ae98398cce1c2e3f6044917a
https://doi.org/10.1534/genetics.112.139105
https://doi.org/10.1534/genetics.112.139105
Publikováno v:
Plasmid. 63:119-127
Escherichia coli DNA-unwinding protein RecQ has roles in the regulation of general recombination and the processing of stalled replication forks. In this study, we found that knockout of the recQ gene in combination with xonA xseA recJ mutations, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d31a6441b944582cda342240fbea65
https://doi.org/10.1016/j.plasmid.2009.12.001
https://doi.org/10.1016/j.plasmid.2009.12.001
Publikováno v:
Biotechnology and Bioengineering. 95:1052-1060
To obtain a cell line that maintains stability of gene expression is important for industrial production of therapeutic proteins from recombinant cells. In this study, we attempted to improve the stability of expression of an exogenous gene by using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd10d7a41f678e76bf96afba9b630026
https://doi.org/10.1002/bit.21058
https://doi.org/10.1002/bit.21058
Publikováno v:
Plasmid. 50:202-212
Illegitimate (non-homologous) recombination requires little or no sequence homology between recombining DNAs and has been regarded as being a process distinct from homologous recombination, which requires a long stretch of homology between recombinin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b540cef9abdd2ccd318106ca5bbdeb0d
https://doi.org/10.1016/j.plasmid.2003.07.001
https://doi.org/10.1016/j.plasmid.2003.07.001