Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Kohji, Moriishi"'
Autor:
Ayaka Washizaki, Asako Murayama, Megumi Murata, Tomoko Kiyohara, Keigo Yato, Norie Yamada, Hussein Hassan Aly, Tomohisa Tanaka, Kohji Moriishi, Hironori Nishitsuji, Kunitada Shimotohno, Yasumasa Goh, Ken J. Ishii, Hiroshi Yotsuyanagi, Masamichi Muramatsu, Koji Ishii, Yoshimasa Takahashi, Ryosuke Suzuki, Hirofumi Akari, Takanobu Kato
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The hepatitis B vaccine is recognised as the most effective approach in reducing hepatitis-B-related morbidity; vaccine-escape mutations are however capable of infecting vaccinated individuals. In this work, authors aim to establish a hepatitis B vac
Externí odkaz:
https://doaj.org/article/eab3ce3f48a74871a664e7bab6a1dc86
Autor:
Yoichi Miyamoto, Yumi Itoh, Tatsuya Suzuki, Tomohisa Tanaka, Yusuke Sakai, Masaru Koido, Chiaki Hata, Cai-Xia Wang, Mayumi Otani, Kohji Moriishi, Taro Tachibana, Yoichiro Kamatani, Yoshihiro Yoneda, Toru Okamoto, Masahiro Oka
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The SARS-CoV-2 ORF6, an antagonist of interferon-mediated antiviral signaling, directly binds to STAT1 and prevents its nuclear localization.
Externí odkaz:
https://doaj.org/article/ab4f7dbe07584f11b248243e57c5400c
Autor:
Teruhime Otoguro, Tomohisa Tanaka, Hirotake Kasai, Nobuhiro Kobayashi, Atsuya Yamashita, Takasuke Fukuhara, Akihide Ryo, Moto Fukai, Akinobu Taketomi, Yoshiharu Matsuura, Kohji Moriishi
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 634-649 (2021)
Compared with each monoinfection, coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is well known to increase the risks of developing liver cirrhosis and hepatocellular carcinoma. However, the mechanism by which HBV/HCV coinfection
Externí odkaz:
https://doaj.org/article/6ade7581902640a09e86ab194d84eb14
Autor:
Takashi Honda, Norie Yamada, Asako Murayama, Masaaki Shiina, Hussein Hassan Aly, Asuka Kato, Takanori Ito, Yoji Ishizu, Teiji Kuzuya, Masatoshi Ishigami, Yoshiki Murakami, Tomohisa Tanaka, Kohji Moriishi, Hironori Nishitsuji, Kunitada Shimotohno, Tetsuya Ishikawa, Mitsuhiro Fujishiro, Masamichi Muramatsu, Takaji Wakita, Takanobu Kato
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1583-1598 (2021)
Background & Aims: To provide an adequate treatment strategy for chronic hepatitis B, it is essential to know which patients are expected to have a good prognosis and which patients do not require therapeutic intervention. Previously, we identified t
Externí odkaz:
https://doaj.org/article/936b7d4f3a05426180767516fa5fb8ee
Autor:
Yuichi Akahori, Hiroki Kato, Takashi Fujita, Kohji Moriishi, Yasuhito Tanaka, Koichi Watashi, Michio Imamura, Kazuaki Chayama, Takaji Wakita, Makoto Hijikata
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Recent development of hepatitis B virus (HBV) culture systems has made it possible to analyze the almost all steps of the viral life cycle. However, the reproducibility of interaction between HBV and host cells seemed inaccurate in those sys
Externí odkaz:
https://doaj.org/article/24c87ff8e1ec41cd8e076d743a800587
Autor:
Takashi Okura, Kazuya Shirato, Masatoshi Kakizaki, Satoko Sugimoto, Shutoku Matsuyama, Tomohisa Tanaka, Yohei Kume, Mina Chishiki, Takashi Ono, Kohji Moriishi, Masashi Sonoyama, Mitsuaki Hosoya, Koichi Hashimoto, Katsumi Maenaka, Makoto Takeda
Publikováno v:
Pathogens, Vol 11, Iss 8, p 877 (2022)
In this study, we show that the coronavirus (CoV) genome may encode many functional hydrophobic alpha-helical peptides (HAHPs) in overlapping reading frames of major coronaviral proteins throughout the entire viral genome. These HAHPs can theoretical
Externí odkaz:
https://doaj.org/article/73cffa1b160c4ef8b34db6febea55f2e
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 5, Pp 494-503 (2019)
TP63 (p63), a member of the tumor suppressor TP53 (p53) gene family, is essential for ectodermal tissue development and suppresses malignant progression of carcinomas. The most abundant isoform, ΔNp63α (referred to as p63), lacks the N-terminal tra
Externí odkaz:
https://doaj.org/article/2ee5285ba49846f0b821ae6b4bc3b401
Autor:
Takuma Izumi, Yuhei Morioka, Syun-ichi Urayama, Daisuke Motooka, Tomokazu Tamura, Takahiro Kawagishi, Yuta Kanai, Takeshi Kobayashi, Chikako Ono, Akinari Morinaga, Takahiro Tomiyama, Norifumi Iseda, Yukiko Kosai, Shoichi Inokuchi, Shota Nakamura, Tomohisa Tanaka, Kohji Moriishi, Hiroaki Kariwa, Tomoharu Yoshizumi, Masaki Mori, Yoshiharu Matsuura, Takasuke Fukuhara
Publikováno v:
Viruses, Vol 13, Iss 7, p 1310 (2021)
Although viruses infect various organs and are associated with diseases, there may be many unidentified pathogenic viruses. The recent development of next-generation sequencing technologies has facilitated the establishment of an environmental viral
Externí odkaz:
https://doaj.org/article/e599571b323b439581c553d16d2bec63
Autor:
Iyoko Katoh, Fuminori Tanabe, Hirotake Kasai, Kohji Moriishi, Noriko Shimasaki, Katsuaki Shinohara, Yukiko Uchida, Tomoko Koshiba, Soichi Arakawa, Michiko Morimoto
Publikováno v:
Frontiers in Public Health, Vol 7 (2019)
Personal protective gowns and coveralls are classified based on barrier efficiency that validates protection from fluid penetration under certain pressures. Materials standardized in this system have been found suitable for emergency medical practice
Externí odkaz:
https://doaj.org/article/d1ba52ac617a43018be9fc6cc19a8f09
Autor:
Yuichiro Suzuki, Shinya Maekawa, Nobutoshi Komatsu, Mitsuaki Sato, Akihisa Tatsumi, Mika Miura, Shuya Matsuda, Masaru Muraoka, Natsuko Nakakuki, Fumitake Amemiya, Shinichi Takano, Mitsuharu Fukasawa, Yasuhiro Nakayama, Tatsuya Yamaguchi, Taisuke Inoue, Tadashi Sato, Minoru Sakamoto, Atsuya Yamashita, Kohji Moriishi, Nobuyuki Enomoto
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212559 (2019)
AimDeletions are observed frequently in the preS1/S2 region of hepatitis B virus (HBV) genome, in association with liver disease advancement. However, the most significant preS1/S2 region and its influences on viral markers are unclear.MethodsThe pre
Externí odkaz:
https://doaj.org/article/ac07c23d116a47d083bcfc91d7051d24