Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Kohji, Itoh"'
Autor:
Daisuke Tsuji, Atsushi Nakayama, Riko Yamamoto, Shuji Nagano, Takashi Taniguchi, Ryota Sato, Sangita Karanjit, Naoki Muguruma, Tetsuji Takayama, Kohji Itoh, Kosuke Namba
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-11 (2023)
Photoactive dyes can show promising cytotoxicity via reactive oxygen species generated by photoirradiation, however, the cytotoxicity of small molecule dyes is typically weak. Here, the authors develop 1,3a,6a-triazapentalene derivatives exhibiting s
Externí odkaz:
https://doaj.org/article/600a82412aef46b9870f796b42eaeb9b
Autor:
Yuto Horii, Toshiki Iniwa, Masayoshi Onitsuka, Jun Tsukimoto, Yuki Tanaka, Hironobu Ike, Yuri Fukushi, Haruna Ando, Yoshie Takeuchi, So-ichiro Nishioka, Daisuke Tsuji, Mariko Ikuo, Naoshi Yamazaki, Yoshiharu Takiguchi, Naozumi Ishimaru, Kohji Itoh
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 297-310 (2022)
Galactosialidosis (GS) is a lysosomal cathepsin A (CTSA) deficiency. It associates with a simultaneous decrease of neuraminidase 1 (NEU1) activity and sialylglycan storage. Central nervous system (CNS) symptoms reduce the quality of life of juvenile/
Externí odkaz:
https://doaj.org/article/c205affe2a714860b2af6ebf4b800e26
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:1609-1615
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0caafac7d8719f5a98a2ba3f3feb0ca1
https://doi.org/10.1248/bpb.b22-00131
https://doi.org/10.1248/bpb.b22-00131
Publikováno v:
Journal of Natural Medicines. 77:173-179
Three new farnesylated coumarins, communiferulins A-C (1-3), and a farnesylated chromone, ferchromone (4), were isolated from the roots of an Apiaceous plant Ferula communis. Their structures including the relative configurations were elucidated by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022d5dba6bef2a4d56e74fb76730f531
https://doi.org/10.1007/s11418-022-01657-8
https://doi.org/10.1007/s11418-022-01657-8
Autor:
Hiroki Tanaka, Daisuke Tsuji, Ryosuke Watanabe, Yukiya Ohnishi, Shindai Kitaguchi, Ryuto Nakae, Hiromi Teramoto, Jun Tsukimoto, Yuto Horii, Kohji Itoh
Publikováno v:
Journal of Inherited Metabolic Disease. 45:1191-1202
Lysosomal storage disorders (LSDs) are inherited metabolic diseases caused by genetic defects in lysosomal enzymes or related factors. LSDs are associated with excessive accumulation of natural substrates in lysosomes leading to central nervous syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ba4f2396644c6f080f57a44c2a20a4
https://doi.org/10.1002/jimd.12558
https://doi.org/10.1002/jimd.12558
Autor:
Naonobu Tanaka, Yuki Yoshino, Fusako Nakano, Shin-ichiro Kurimoto, Kazuyoshi Kawazoe, Daisuke Tsuji, Kohji Itoh, Shun-Lin Li, Han-Dong Sun, Yoshihisa Takaishi, Yoshiki Kashiwada
Publikováno v:
Journal of Natural Products. 85:1180-1185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec9e6e84f18f0be747b14a3e9283ca6
https://doi.org/10.1021/acs.jnatprod.1c01069
https://doi.org/10.1021/acs.jnatprod.1c01069
Autor:
Sanghoon Lee, Naonobu Tanaka, Sakura Takahashi, Daisuke Tsuji, Sang-Yong Kim, Mareshige Kojoma, Kohji Itoh, Jun’ichi Kobayashi, Yoshiki Kashiwada
Publikováno v:
Marine Drugs, Vol 18, Iss 9, p 455 (2020)
Exploration for specialized metabolites of Okinawan marine sponges Agelas spp. resulted in the isolation of five new bromopyrrole alkaloids, agesasines A (1) and B (2), 9-hydroxydihydrodispacamide (3), 9-hydroxydihydrooroidin (4), and 9E-keramadine (
Externí odkaz:
https://doaj.org/article/96a02758bdfb40f69559234f0a000b95
Autor:
Jun Tsukimoto, Yoshie Takeuchi, Yuto Horii, Toshiki Iniwa, Yuri Fukushi, So-ichiro Nishioka, Kohji Itoh
Publikováno v:
ACS Applied Bio Materials. 5:205-213
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca06e38919d8fd3585b08dfb693684c6
https://doi.org/10.1021/acsabm.1c01043
https://doi.org/10.1021/acsabm.1c01043
Autor:
Naonobu Tanaka, Ikko Shibata, Yusuke Tasaki, Yuki Yoshino, Daisuke Tsuji, Feng-Lai Lu, Xiao-Jie Yan, Xue-Rong Yang, Kohji Itoh, Reiko Akagi, Dian-Peng Li, Yoshiki Kashiwada
Publikováno v:
Fitoterapia. 168:105539
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bd9b1da92f487b191e88b8459e3f87d
https://doi.org/10.1016/j.fitote.2023.105539
https://doi.org/10.1016/j.fitote.2023.105539
Autor:
Kanji Niwa, Kohji Itoh, Yoshiki Kashiwada, Naonobu Tanaka, Nilufar Z. Mamadalieva, Daisuke Tsuji, Seita Kajihara
Publikováno v:
Organic Letters. 22:7667-7670
Structurally unique C28 terpenoids, perovsfolins A (1) and B (2), were isolated from the aerial parts of an Uzbek medicinal plant, Perovskia scrophulariifolia (Lamiaceae). Their chemical structures including an unprecedented 6/8/6/6/6 pentacyclic car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3ae29444a917a842739b783a0b00b9c
https://doi.org/10.1021/acs.orglett.0c02855
https://doi.org/10.1021/acs.orglett.0c02855