Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kohichi Uchida"'
Publikováno v:
Cellular and Molecular Neurobiology. 19:79-86
1. Accumulating evidence indicates that damaged brain functions can be ameliorated in a variety of animal models by the grafting of fetal neuronal cell or tissue into damaged brain. Clinical trials are under way to determine whether human fetal mesen
Autor:
Masaaki Korenaga, Teruaki Kimura, Kohzoh Kayano, Masaaki Masuhara, Satoyoshi Yamashita, Kiwamu Okita, Kohji Tanigawa, Keisuke Hino, Isao Sakaida, Kohichi Uchida, Chieko Suzuki
Publikováno v:
Hepatology Research. 12:23-30
To assess the involvement of GB virus C (GBV-C) or hepatitis B virus (HBV) infection in fulminant hepatitis of unknown etiology, GBV-C RNA and HBV DNA in serum were retrospectively assayed by polymerase chain reaction (PCR) in six patients with fulmi
Publikováno v:
Neuroscience Letters. 109:282-286
In the present study, tyrosine hydroxylase (TH; EC 1.14.16.2) cDNA was transfected into cultured fibroblasts and the production of l -3,4-dihydroxyphenylalanine ( l -DOPA) was determined. Type 2 TH cDNA was transfected into fibroblasts (NRK-49F) deri
Autor:
D J Gerard, Eric Jauniaux, Kohichi Uchida, Henry F. Bradford, Gerald M. Stern, Michael J. Hurley
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 108(7)
Obtaining an adequate supply of foetal dopaminergic tissue to treat Parkinson's disease by neural transplantation can be difficult. In this study primary cultures of human foetal cerebral cortex cells were transfected, using cationic lipids, with a e
Autor:
Kohichi Uchida, Shigeo Toya
Publikováno v:
The Keio journal of medicine. 45(2)
Accumulating evidence has shown that functional recoveries in various kinds of animal models of neurodegenerative diseases can be achieved by grafting fetal neurons into the brain. On the basis of these successful results, clinical trials are under w
Publikováno v:
Experimental neurology. 132(2)
Neural plate cells from the early embryo may have a number of important advantages as donor material for the delivery of foreign genes into the diseased adult central nervous system (CNS). Mesencephalic neural plate from transgenic GT4-2 mice was use
Publikováno v:
Developmental neuroscience. 14(2)
Fibroblasts (NRK-49F) were transfected with human type 2 tyrosine hydroxylase (TH; EC 1.14.16.29) cDNA, to clarify the mechanism involved in amelioration of parkinsonism by intracerebral grafting of catecholaminergic neurons and to investigate its po
Autor:
Shinichi Kohsaka, Sadao Matsuura, Shigeo Toya, Toshiharu Nagatsu, Akira Ishii, Kohichi Uchida, Masako Hagihara, Kazutoshi Kiuchi, Norio Kaneda
Publikováno v:
Neurochemistry international. 17(4)
l-erythro-5,6,7,8-Tetrahydrobiopterin (BH(4)), which is the cofactor of aromatic amino acid hydroxylases, plays an important role in the biosyntheses of monoamine neurotransmitters. BH(4) exists as natural (6R)- and unnatural (6S)-isomers. In our pre
Autor:
Shigeo Toya, Norio Kaneda, Ken Takamatsu, Shinichi Kohsaka, Toshiharu Nagatsu, Yasuzo Tsukada, Keisuke Fujita, Yoshikazu Kurosawa, Kohichi Uchida
Publikováno v:
Journal of Neurochemistry. 53:728-732
In the present study, we obtained genetically manipulated nonneuronal cells which synthesize a catecholamine precursor for future use in intracerebral grafting. Human type 1 tyrosine hydroxylase (TH; EC 1.14.16.2) cDNA was inserted into eukaryotic ex
Autor:
Shinichi Kohsaka, Shigeo Toya, Norio Kaneda, Ken Takamatsu, Keisuke Fujita, Yoshikazu Kurosawa, Kohichi Uchida, Yasuzo Tsukada, Toshiharu Nagatsu
Publikováno v:
Proceedings of the Japan Academy, Series B. 64:290-293