Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kohei Wagatsuma"'
Autor:
Takehiro Hirano, Yujiro Kawakami, Sayaka Nakabayashi, Kohei Wagatsuma, Keisuke Ishigami, Yoshiharu Masaki, Ayako Murota, Masatoshi Kanda, Shintaro Sugita, Kenji Notohara, Hiroshi Nakase
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 8, Pp 1089-1092 (2023)
Immunoglobulin G4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by the infiltration of IgG4-positive plasma cells and fibrosis in organs throughout the body. IgG4-RD involvement in the gastrointestinal (GI) tract (IgG4-re
Externí odkaz:
https://doaj.org/article/699aa4b065684965b878bfc8682d2df4
Autor:
Yasunao Numata, Noriyuki Akutsu, Keisuke Ishigami, Hideyuki Koide, Kohei Wagatsuma, Masayo Motoya, Shigeru Sasaki, Hiroshi Nakase
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101270- (2022)
Immunotherapy using anti-programmed death 1 ligand 1 (PD-L1) antibodies has shown clinical efficacy against hepatocellular carcinoma (HCC) and is recognized as the first-line treatment for unresectable HCC. PD-L1 expression is affected by various cyt
Externí odkaz:
https://doaj.org/article/5cfff7200b99464d8ab4ae22cd57a5a1
Autor:
Tomoya Iida, Daisuke Hirayama, Naoki Minami, Minoru Matsuura, Kohei Wagatsuma, Kentaro Kawakami, Kanna Nagaishi, Masanori Nojima, Hiroki Ikeuchi, Seiichi Hirota, Ryutaro Shirakawa, Hisanori Horiuchi, Hiroshi Nakase
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 277-293 (2020)
Background & Aims: Ral guanosine triphosphatase–activating protein α2 (RalGAPα2) is the major catalytic subunit of the negative regulators of the small guanosine triphosphatase Ral, a member of the Ras subfamily. Ral regulates tumorigenesis and i
Externí odkaz:
https://doaj.org/article/3ebe0fa622644546804ecb822960ab18
Publikováno v:
Life, Vol 11, Iss 12, p 1375 (2021)
The number of patients with inflammatory bowel disease (IBD) is increasing worldwide. Endoscopy is the gold standard to assess the condition of IBD. The problem with this procedure is that the burden and cost on the patient are high. Therefore, the i
Externí odkaz:
https://doaj.org/article/d1851147554e4054b6cb1e1cc74d019d
Autor:
Yujiro Kawakami, Yumemi Takada, Keisuke Ishigami, Takehiro Hirano, Kohei Wagatsuma, Yoshiharu Masaki, Ayako Murota, Masayo Motoya, Mitsuhiro Tsujiwaki, Hiroki Takahashi, Hiroshi Nakase
Publikováno v:
JGH Open, Vol 5, Iss 1, Pp 151-152 (2021)
Externí odkaz:
https://doaj.org/article/69f7470aea68455bb3279c1548ddb526
Autor:
Tadashi Ichimiya, Tsukasa Yamakawa, Takehiro Hirano, Yoshihiro Yokoyama, Yuki Hayashi, Daisuke Hirayama, Kohei Wagatsuma, Takao Itoi, Hiroshi Nakase
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 8974 (2020)
Autophagy refers to the process involving the decomposition of intracellular components via lysosomes. Autophagy plays an important role in maintaining and regulating cell homeostasis by degrading intracellular components and providing degradation pr
Externí odkaz:
https://doaj.org/article/4588b000e4824f529798ade314acd901
Autor:
Kohei Wagatsuma, Hiroshi Nakase
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8145 (2020)
The inflammasome is an intracellular molecular complex, which is mainly involved in innate immunity. Inflammasomes are formed in response to danger signals, associated with infection and injury, and mainly regulate the secretion of interleukin-1β an
Externí odkaz:
https://doaj.org/article/7a17415ebfec4bf98b7e77c9448d5dbc
Autor:
Takehiro Hirano, Daisuke Hirayama, Kohei Wagatsuma, Tsukasa Yamakawa, Yoshihiro Yokoyama, Hiroshi Nakase
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3062 (2020)
Patients with chronic inflammatory bowel diseases are at an increased risk of developing colitis-associated cancer (CAC). Chronic inflammation positively correlates with tumorigenesis. Similarly, the cumulative rate of incidence of developing CAC inc
Externí odkaz:
https://doaj.org/article/7285352c976649b78b22a9b59c29cdf3
Autor:
Yoshihiro Yokoyama, Tsukasa Yamakawa, Takehiro Hirano, Tomoe Kazama, Daisuke Hirayama, Kohei Wagatsuma, Hiroshi Nakase
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2438 (2020)
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus (the human herpesvirus 5) and an opportunistic pathogen that primarily infects HIV-positive and other immuno-compromised patients. Retrospective studies in the field of inflammatory bowel disea
Externí odkaz:
https://doaj.org/article/a897c2d0f2194667972e6ba760fa92e8
Autor:
Tomoya Iida, Hiroyuki Kaneto, Kohei Wagatsuma, Hajime Sasaki, Yumiko Naganawa, Suguru Nakagaki, Shuji Satoh, Haruo Shimizu, Hiroshi Nakase
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190665 (2018)
The Endoscopic procedures for common bile duct (CBD) stones are reportedly safe in the elderly patients. However, the definition of the elderly is different in each report. If the elderly are defined as people aged 85 years or older, data on the effe
Externí odkaz:
https://doaj.org/article/86a286f62c624ed6b7394f7914e887be