Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kohei Toh"'
Autor:
Kohei Toh, Kosuke Nishio, Reiko Nakagawa, Syusuke Egoshi, Masahiro Abo, Amelie Perron, Shin-ichi Sato, Naoki Okumura, Noriko Koizumi, Kosuke Dodo, Mikiko Sodeoka, Motonari Uesugi
Publikováno v:
Journal of the American Chemical Society. 144:20171-20176
Visible light, particularly in the blue region of the spectrum, can cause cell dysfunction through the generation of singlet oxygen, contributing to cellular aging and age-related pathologies. Although photooxidation of nucleic acids, lipids, and ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e8d8ee74a276a991a55ca22c49d5d8
https://doi.org/10.1021/jacs.2c07180
https://doi.org/10.1021/jacs.2c07180
Autor:
Kosuke Nishio, Kohei Toh, Amelie Perron, Masato Goto, Masahiro Abo, Yuichi Shimakawa, Motonari Uesugi
Publikováno v:
Journal of the American Chemical Society. 144:16720-16725
Melanin is an organic material biosynthesized from tyrosine in pigment-producing cells. The present study reports a simple method to generate tailored functional materials in mammalian cells by chemically fabricating intracellular melanin. Our approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1befd4c1b20032ebca3799101f5c84d
https://doi.org/10.1021/jacs.2c06555
https://doi.org/10.1021/jacs.2c06555
Publikováno v:
Organic letters. 24(35)
A multiselective Diels–Alder (DA) reaction of α-arylacroleins with cyclopentadiene using BBr3-assisted chiral BINOL-derived phosphoric acid catalysts has been developed. This unusual exo- and enantioselective DA reaction can be multicontrolled by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0407824ac5f8294c8d9a444cfc6ff3e
https://pubmed.ncbi.nlm.nih.gov/36017904
https://pubmed.ncbi.nlm.nih.gov/36017904
Autor:
Kai Matsui, Kohei Toh, Kazuaki Ishihara, Jun-ya Hasegawa, Jie Qi Ng, Manabu Hatano, Takuya Mochizuki, Manussada Ratanasak, Hiro Arima
Publikováno v:
ACS catalysis. 11(1):199-207
A highly chemoselective transesterification of methyl (meth)acrylates catalyzed by sterically demanding 2,6-di-tert-butyl-4-methylphenol-derived NaOAr or Mg(OAr)(2) was developed. The desired transesterification proceeded without the undesired Michae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c20d7e3bd1fd0f31c3dc76606d70a4
http://hdl.handle.net/2115/83756
http://hdl.handle.net/2115/83756
Publikováno v:
Organic Letters. 22:9614-9620
A hydrogen bonding network in chiral Bronsted acid catalysts is important for the construction of a chiral cavity and the enhancement of catalytic activity. In this regard, we developed a highly enantioselective aza-Friedel-Crafts reaction of indoles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::953cf15e3e6aac612c8a825c361b1a37
https://doi.org/10.1021/acs.orglett.0c03662
https://doi.org/10.1021/acs.orglett.0c03662
Autor:
Yejin Jung, Naotaka Noda, Junichiro Takaya, Masahiro Abo, Kohei Toh, Ken Tajiri, Changyi Cui, Lu Zhou, Shin-ichi Sato, Motonari Uesugi
Publikováno v:
ACS chemical biology. 17(2)
Covalent inhibitors of enzymes are increasingly appreciated as pharmaceutical seeds, yet discovering non-cysteine-targeting inhibitors remains challenging. Herein, we report an intriguing experience during our activity-based proteomic screening of 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7d2e5c9d3b854f99f538d750e098f1
https://pubmed.ncbi.nlm.nih.gov/35076225
https://pubmed.ncbi.nlm.nih.gov/35076225
Autor:
Kohei Toh
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 80:64-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e961199dd2ddbd99a0adf6a50a6dae9
https://doi.org/10.5059/yukigoseikyokaishi.80.64
https://doi.org/10.5059/yukigoseikyokaishi.80.64
Autor:
Manabu Hatano, Akira Sakakura, Takuya Mochizuki, Kazuaki Ishihara, Haruka Okamoto, Kohei Toh, Hidefumi Nakatsuji
Publikováno v:
Synthesis. 50:4577-4590
Chiral BINOL-derived pyrophosphoric acid catalysts were developed and used for the regio- and enantioselective aza-Friedel–Crafts reaction of phenols with aldimines. ortho/para-Directing phenols could react at the para-position selectively with mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f03d77b35913b167c5489e289304c3
https://doi.org/10.1055/s-0037-1610250
https://doi.org/10.1055/s-0037-1610250
Autor:
Kenji Yamashita, Yoshihiro Ogura, Kohei Toh, Yurika Yoshida, Kazuaki Ishihara, Yuji Tabata, Manabu Hatano
Publikováno v:
Green Chemistry. 20:1193-1198
Environmentally benign metal-free tetramethylammonium methyl carbonate is effective as a catalyst for the chemoselective, scalable, and reusable transesterification of various esters and alcohols in common organic solvents. In situ-generated highly a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81d001a2c59c835217f7b6d56249f5b
https://doi.org/10.1039/c7gc03858e
https://doi.org/10.1039/c7gc03858e
Autor:
Haruka Okamoto, Manabu Hatano, Kazuaki Ishihara, Taro Kawakami, Kohei Toh, Hidefumi Nakatsuji, Akira Sakakura
Publikováno v:
Chemical Science
Chiral C2- and C1-symmetric BINOL-derived bis(phosphoric acid) catalysts facilitated the enantioselective aza-Friedel–Crafts reaction of 2-methoxyfuran with α-ketimino esters.
Chiral C2- and C1-symmetric BINOL-derived bis(phosphoric acid) cat
Chiral C2- and C1-symmetric BINOL-derived bis(phosphoric acid) cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb7abf710a3b241139e45dc926f8917
https://doi.org/10.1039/c8sc02290a
https://doi.org/10.1039/c8sc02290a