Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kohei Saeki"'
Autor:
Kosuke Kobayashi, Reika Deja Takemura, Jiro Miyamae, Ikki Mitsui, Kohei Murakami, Kenji Kutara, Kohei Saeki, Teppei Kanda, Yasuhiko Okamura, Akihiko Sugiyama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Canine pulmonary adenocarcinoma (PAC) resembles human lung tumors in never-smokers, but it is rarer than human pulmonary adenocarcinoma. Therefore, research on canine PAC is challenging. In the present study, we successfully established vari
Externí odkaz:
https://doaj.org/article/0261b2e5f34b421aafff2e0f4fba12b1
Autor:
Ryohei Yoshitake, Hitomi Mori, Desiree Ha, Xiwei Wu, Jinhui Wang, Xiaoqiang Wang, Kohei Saeki, Gregory Chang, Hyun Jeong Shim, Yin Chan, Shiuan Chen
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Intratumour heterogeneity is a hallmark of most solid tumours, including breast cancers. We applied spatial transcriptomics and single‐cell RNA‐sequencing on patient‐derived xenografts (PDXs) to profile spatially resolved ce
Externí odkaz:
https://doaj.org/article/c912d0814431403cb39c58c440c17054
Autor:
Kohei Saeki, Gregory Chang, Noriko Kanaya, Xiwei Wu, Jinhui Wang, Lauren Bernal, Desiree Ha, Susan L. Neuhausen, Shiuan Chen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Kohei Saeki et al. present a mammary cell atlas derived from mouse and human single-cell RNA-sequence data. They characterize key life stages in which the mammary gland undergoes complex remodeling and, using breast cancer expression data, infer cell
Externí odkaz:
https://doaj.org/article/bf5f51d3ae774ad78c6e50dc269ae7a4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Fibroblasts have been shown to be one of the essential players for mammary gland organization. Here, we identify two major types of mouse mammary gland fibroblasts through single-cell RNA sequencing analysis: Dpp4+ fibroblasts and Dpp4- fibroblasts.
Externí odkaz:
https://doaj.org/article/5a9c9344b700420bad7020a24bf486d0
Autor:
Kohei Saeki, Gregory Chang, Noriko Kanaya, Xiwei Wu, Jinhui Wang, Lauren Bernal, Desiree Ha, Susan L. Neuhausen, Shiuan Chen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/c1689a809a2d4095a8e457d7b9c96bc7
Autor:
Sho Yoshimoto, Daiki Kato, Satoshi Kamoto, Kie Yamamoto, Masaya Tsuboi, Masahiro Shinada, Namiko Ikeda, Yuiko Tanaka, Ryohei Yoshitake, Shotaro Eto, Kohei Saeki, James Chambers, Ryohei Kinoshita, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa
Publikováno v:
Heliyon, Vol 5, Iss 7, Pp e02004- (2019)
The human epidermal growth factor receptor 2 (HER2) is expressed in various human cancers including thyroid cancers (TC) and is used as a diagnostic marker and therapeutic target. Canine TC (cTC), the most common endocrine malignancy in dogs, shows a
Externí odkaz:
https://doaj.org/article/c826c08557774a318c223e2cf03be560
Autor:
Shotaro Eto, Kohei Saeki, Ryohei Yoshitake, Sho Yoshimoto, Masahiro Shinada, Namiko Ikeda, Satoshi Kamoto, Yuiko Tanaka, Daiki Kato, Shingo Maeda, Masaya Tsuboi, James Chambers, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218382 (2019)
Canine urothelial carcinoma (cUC) is the most common tumor of the lower urinary tract in dogs. Although chemotherapy and radical surgery have improved the overall survival, most dogs with cUC succumb to metastasis or recurrence. Therefore, the develo
Externí odkaz:
https://doaj.org/article/74e82af3ac9642e29d29432edaf683fa
Autor:
Masahiro Shinada, Daiki Kato, Satoshi Kamoto, Sho Yoshimoto, Masaya Tsuboi, Ryohei Yoshitake, Shotaro Eto, Namiko Ikeda, Kohei Saeki, Yuko Hashimoto, Yosuke Takahashi, James Chambers, Kazuyuki Uchida, Mika K. Kaneko, Naoki Fujita, Ryohei Nishimura, Yukinari Kato, Takayuki Nakagawa
Publikováno v:
Cells, Vol 9, Iss 5, p 1136 (2020)
Podoplanin (PDPN), a small transmembrane mucin-like glycoprotein, is ectopically expressed. It is also known to be linked with several aspects of tumor malignancy in some types of human tumors, including invasion, metastasis, and cancer stemness. How
Externí odkaz:
https://doaj.org/article/3b34a7c8387b45768d7edbc917ff1d65
Autor:
Hiroto Fujii, Shintaro Arai, Kohei Saeki, Ryohei Yoshitake, Eri Iwata, Suguru Kameda, Ataru Yamaoka
Publikováno v:
Journal of Signal Processing (1342-6230); Jul2024, Vol. 28 Issue 4, p145-149, 5p
Autor:
Hitomi Mori, Kohei Saeki, Gregory Chang, Jinhui Wang, Xiwei Wu, Noriko Kanaya, George Somlo, Shiuan Chen
Publikováno v:
Cancer Research. 83:P3-11
Background: While estrogen typically promotes the progression of hormone-dependent breast cancer via the activation of estrogen receptor (ER)-α, estrogen-induced suppression of ER+ breast cancer has been clinically observed. Our previous study demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab3333fb0678cd35c46bf3dbe2c5e14
https://doi.org/10.1158/1538-7445.sabcs22-p3-11-05
https://doi.org/10.1158/1538-7445.sabcs22-p3-11-05