Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Kohei Karasaki"'
1
Akademický článek
Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin‐Deficient Mice via Upregulation of Angiotensin (1–7)
Autor: Kohei Karasaki, Hiroki Kokubo, Batmunkh Bumdelger, Nobuchika Kaji, Chiemi Sakai, Mari Ishida, Masao Yoshizumi
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 3 (2023)
Background Angiotensin II type 1 receptor blockers (ARBs) have been shown to limit the growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial. This study aimed to investigate the molecular mechanism underlying the protective e
Externí odkaz: https://doaj.org/article/69fc987909204bc78c6c2aefbedd3d19
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2
Akademický článek
Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation
Autor: Wenyu Hu, Anqi Dong, Kohei Karasaki, Shota Sogabe, Daiki Okamoto, Masato Saigo, Mari Ishida, Masao Yoshizumi, Hiroki Kokubo
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Bmp plays an important role in cardiomyocyte differentiation, but the function of Smad4 in Bmp signaling remains elusive. Here, we show that disruption of the Smad4 gene in cardiac progenitors expressing Sfrp5 led to embryonic lethality with
Externí odkaz: https://doaj.org/article/facdf754252742c58ba07118dc45ac9e
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3
Akademický článek
Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation.
Autor: Batmunkh Bumdelger, Mikage Otani, Kohei Karasaki, Chiemi Sakai, Mari Ishida, Hiroki Kokubo, Masao Yoshizumi
Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0235553 (2020)
Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl2-induced ane
Externí odkaz: https://doaj.org/article/4bd1a37817e74921998e426e34d7bef6
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4
Akademický článek
Changes in lipid metabolism and capillary density of the skeletal muscle following low-intensity exercise training in a rat model of obesity with hyperinsulinemia.
Autor: Naoto Fujita, Saki Aono, Kohei Karasaki, Fumi Sera, Tomoyuki Kurose, Hidemi Fujino, Susumu Urakawa
Publikováno v: PLoS ONE, Vol 13, Iss 5, p e0196895 (2018)
Although exercise is effective in improving obesity and hyperinsulinemia, the exact influence of exercise on the capillary density of skeletal muscles remains unknown. The aim of this study was to investigate the effects of low-intensity exercise tra
Externí odkaz: https://doaj.org/article/976406f083ea4a82bdf840844c48e353
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6
Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation
Autor: Daiki Okamoto, Mari Ishida, Masato Saigo, Anqi Dong, Hiroki Kokubo, Shota Sogabe, Kohei Karasaki, Masao Yoshizumi, Wenyu Hu
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Bmp plays an important role in cardiomyocyte differentiation, but the function of Smad4 in Bmp signaling remains elusive. Here, we show that disruption of the Smad4 gene in cardiac progenitors expressing Sfrp5 led to embryonic lethality with hypoplas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5cf0ae368ba313a9d3d7da3baed5bf
https://doaj.org/article/facdf754252742c58ba07118dc45ac9e
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8
Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation
Autor: Mikage Otani, Masao Yoshizumi, Kohei Karasaki, Batmunkh Bumdelger, Hiroki Kokubo, Chiemi Sakai, Mari Ishida
Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235553 (2020)
Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl2-induced ane
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bd77763e1a79de36d2f47e6acd7917
https://doi.org/10.1371/journal.pone.0235553
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9
Changes in lipid metabolism and capillary density of the skeletal muscle following low-intensity exercise training in a rat model of obesity with hyperinsulinemia
Autor: Saki Aono, Hidemi Fujino, Fumi Sera, Kohei Karasaki, Tomoyuki Kurose, Naoto Fujita, Susumu Urakawa
Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0196895 (2018)
Although exercise is effective in improving obesity and hyperinsulinemia, the exact influence of exercise on the capillary density of skeletal muscles remains unknown. The aim of this study was to investigate the effects of low-intensity exercise tra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9fe11ed20310d79fcdaceea74597c6
https://pubmed.ncbi.nlm.nih.gov/29718998
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