Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kohei Kanata"'
Autor:
Hiroshi Hamada, Bruno Reversade, Artina Metoska, Fui Mee Ng, Jeffrey Hill, Patrick Cozzone, Nithya Baburajendran, Hülya Kayserili, Oz Pomp, Nathalie Escande-Beillard, Joyner Wong, Abigail Loh, Kohei Kanata, Sahar N. Saleem, Joanes Grandjean, Yui Hashimoto, E. Beillard, Umut Altunoglu, Hidetaka Shiratori, Maha S. Zaki
Publikováno v:
Neuron, 107, 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Patients lacking PYCR2, a mitochondrial enzyme that synthesizes proline, display postnatal degenerative microcephaly with hypomyelination. Here we report the crystal structure of the PYCR2 apo-enzyme and show that a novel germline p.Gly249Val mutatio
Publikováno v:
Development. 140:291-300
Testicular development in the mouse is triggered in somatic cells by the function of Sry followed by the activation of fibroblast growth factor 9 (FGF9), which regulates testicular differentiation in both somatic and germ cells. However, the mechanis